Peficitinib API Manufacturers

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Looking for Peficitinib API 944118-01-8?

Description:
Here you will find a list of producers, manufacturers and distributors of Peficitinib. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Peficitinib 
Synonyms:
 
Cas Number:
944118-01-8 
DrugBank number:
DB11708 
Unique Ingredient Identifier:
HPH1166CKX

General Description:

Peficitinib, identified by CAS number 944118-01-8, is a notable compound with significant therapeutic applications. Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.

Classification:

Peficitinib belongs to the class of organic compounds known as pyrrolopyridines. These are compounds containing a pyrrolopyridine moiety, which consists of a pyrrole ring fused to a pyridine. Pyrrole is 5-membered ring consisting of four carbon atoms and one nitrogen atom. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center, classified under the direct parent group Pyrrolopyridines. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Pyrrolopyridines class, specifically within the None subclass.

Categories:

Peficitinib is categorized under the following therapeutic classes: Antineoplastic and Immunomodulating Agents, Bridged-Ring Compounds, Cycloparaffins, Enzyme Inhibitors, Immunologic Factors, Immunosuppressive Agents, Nicotinic Acids, Pyridines, Selective Immunosuppressants. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Peficitinib is a type of Enzyme Replacements/modifiers


Enzyme replacements/modifiers are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various enzyme-related disorders. Enzymes play a vital role in the normal functioning of the body by catalyzing specific biochemical reactions. However, in certain medical conditions, the body may lack or produce dysfunctional enzymes, leading to serious health complications.

Enzyme replacement therapy (ERT) involves administering exogenous enzymes to compensate for the enzyme deficiency in patients. These enzymes are typically derived from natural sources or produced using recombinant DNA technology. By introducing these enzymes into the body, they can effectively substitute the missing or defective enzymes, thereby restoring normal metabolic processes.

On the other hand, enzyme modifiers are API substances that regulate the activity of specific enzymes within the body. These modifiers can either enhance or inhibit the enzyme's function, depending on the therapeutic objective. By modulating enzyme activity, these APIs can restore the balance of enzymatic reactions, leading to improved physiological outcomes.

Enzyme replacements/modifiers have shown remarkable success in treating various genetic disorders, such as Gaucher disease, Fabry disease, and lysosomal storage disorders. Additionally, they have demonstrated potential in managing enzyme deficiencies associated with rare diseases and certain types of cancer.

The development and production of enzyme replacements/modifiers involve rigorous research, formulation optimization, and adherence to stringent quality control measures. Pharmaceutical companies invest substantial resources in developing these APIs to ensure their safety, efficacy, and compliance with regulatory standards.

Overall, enzyme replacements/modifiers represent a vital therapeutic category in modern medicine, offering hope and improved quality of life for patients with enzyme-related disorders.