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Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
---|---|---|---|---|---|---|---|---|
30-Sep-2024 | (Hidden) | China | LUPIN LIMI... | India | DALBAVANCI... | 0.50 | $ @36$-7! | Check all data |
11-Sep-2024 | (Hidden) | China | PAR FORMUL... | India | DALBAVANCI... | No data available | $ @36$-7! | |
28-Aug-2024 | (Hidden) | China | SIMSON PHA... | India | DALBAVANCI... | No data available | $ @36$-7! |
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Established in: 2011
MOQ: 1 g
Employees: 10+
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Established in: 2019
MOQ: 1 kg
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Looking for Dalbavancin API 171500-79-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Dalbavancin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Dalbavancin
- Synonyms:
- dalbavancin B0
- Cas Number:
- 171500-79-1
- DrugBank number:
- DB06219
- Unique Ingredient Identifier:
- B0U42518WL
About Dalbavancin
It's time for some technical information for the ones who understand chemistry: Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin 1. Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing . Its use is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by the following gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), S. pyogenes, S.
agalactiae, S. dysgalactiae, the S. anginosus group (including S. anginosus, S. intermedius, and S. constellatus), and Enterococcus faecalis (vancomycin susceptible strains) 4. Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking .
You can ask the supplier for more technical information about the product.
Dalbavancin is a type of Glycopeptides
Glycopeptides are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in the field of medicinal chemistry and drug development. These complex molecules consist of a peptide chain with one or more attached carbohydrate chains, known as glycans.
Glycopeptides possess unique chemical and structural properties that contribute to their diverse biological activities. They are primarily recognized for their potent antimicrobial properties and are commonly used to combat various bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and other multidrug-resistant strains. This makes them highly valuable in the pharmaceutical industry.
The glycan moieties present in glycopeptides contribute to their mode of action. These carbohydrates aid in the recognition and binding of the glycopeptides to specific bacterial targets, inhibiting cell wall synthesis and disrupting bacterial growth. This mechanism of action sets glycopeptides apart from other classes of antibiotics, making them effective against resistant bacterial strains.
Glycopeptides can be produced through synthetic or semi-synthetic methods, with natural sources such as soil bacteria serving as starting materials. Vancomycin and teicoplanin are examples of well-known glycopeptide antibiotics. Researchers continue to explore the potential of glycopeptides in areas beyond antimicrobial applications, including cancer therapy and drug delivery systems.
In summary, glycopeptides represent a vital subcategory of pharmaceutical APIs with exceptional antimicrobial properties and significant potential in various therapeutic applications. Their complex structure and unique mechanism of action make them valuable assets in the fight against drug-resistant bacteria and other diseases.
Dalbavancin (Glycopeptides), classified under Antibacterials
Antibacterials, a category of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in combating bacterial infections. These APIs are chemical compounds that target and inhibit the growth or kill bacteria, helping to eliminate harmful bacterial pathogens from the body.
Antibacterials are essential for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more. They are commonly prescribed by healthcare professionals to combat both mild and severe bacterial infections.
Within the category of antibacterials, there are different classes and subclasses of APIs, each with distinct mechanisms of action and target bacteria. Some commonly used antibacterials include penicillins, cephalosporins, tetracyclines, macrolides, and fluoroquinolones. These APIs work by interfering with various aspects of bacterial cellular processes, such as cell wall synthesis, protein synthesis, DNA replication, or enzyme activity.
The development and production of antibacterial APIs require stringent quality control measures to ensure their safety, efficacy, and purity. Pharmaceutical manufacturers must adhere to Good Manufacturing Practices (GMP) and follow rigorous testing protocols to guarantee the quality and consistency of these APIs.
As bacterial resistance to antibiotics continues to be a significant concern, ongoing research and development efforts aim to discover and develop new antibacterial APIs. The evolution of antibacterials plays a crucial role in combating emerging bacterial strains and ensuring effective treatment options for infectious diseases.
In summary, antibacterials are a vital category of pharmaceutical APIs used to treat bacterial infections. They are designed to inhibit or kill bacteria, and their development requires strict adherence to quality control standards. By continually advancing research in this field, scientists and pharmaceutical companies can contribute to the ongoing battle against bacterial infections.
Dalbavancin manufacturers | traders | suppliers
We have 4 companies offering Dalbavancin produced in 3 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Apino Pharma Co., Ltd. from China, product country of origin China
- Gnosis Bioresearch S.R.L. from Italy, product country of origin Italy
- Sanofi from France, product country of origin France
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