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Gaboxadol
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Looking for Gaboxadol API 64603-91-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Gaboxadol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Gaboxadol
- Synonyms:
- THIP
- Cas Number:
- 64603-91-4
- DrugBank number:
- DB06554
- Unique Ingredient Identifier:
- K1M5RVL18S
About Gaboxadol
Want to know more about Gaboxadol? Gaboxadol also known as,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of benzodiazepines. Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives.
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Gaboxadol is a type of Hypnotics
Hypnotics belong to the pharmaceutical API category, which refers to a class of drugs primarily used to induce sleep or alleviate insomnia. These substances act on the central nervous system (CNS) to promote sedation and relaxation, aiding individuals in falling asleep and maintaining a healthy sleep pattern.
Hypnotics work through various mechanisms, targeting receptors and neurotransmitters involved in regulating sleep-wake cycles. They can enhance the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that reduces brain activity and induces sedation. By increasing GABAergic signaling, hypnotics help reduce anxiety, calm the mind, and facilitate sleep onset.
Commonly prescribed hypnotics include benzodiazepines, non-benzodiazepine receptor agonists, and melatonin receptor agonists. Benzodiazepines, such as diazepam and temazepam, bind to GABA receptors, intensifying the inhibitory effects of GABA. Non-benzodiazepine receptor agonists like zolpidem and zopiclone act selectively on certain GABA receptors, inducing sleep without causing significant muscle relaxation or antianxiety effects. Melatonin receptor agonists like ramelteon mimic the effects of melatonin, a hormone that regulates the sleep-wake cycle.
Hypnotics are widely prescribed for individuals experiencing sleep disturbances due to various conditions, including insomnia, jet lag, shift work disorder, or other sleep-related disorders. These APIs are manufactured by pharmaceutical companies and can be formulated into different dosage forms, including tablets, capsules, or liquid preparations.
It's essential to note that the use of hypnotics should be carefully monitored, as prolonged or excessive use may lead to dependence, tolerance, or adverse effects. Therefore, consultation with a healthcare professional is necessary to ensure safe and appropriate use of hypnotics for optimal sleep management.
Gaboxadol manufacturers | traders | suppliers
We have 1 companies offering Gaboxadol produced in 1 different countries.
Get in contact with the supplier of your choice:
- H. Lundbeck from Denmark, product country of origin Denmark
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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