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    Indomethacin | compare suppliers & send inquiries for free

    Here you will find a list of producers, manufacturers and traders of Indomethacin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
    Italy Fabbrica Italiana Sintetici (FIS)
    Type: Producer
    Produced in: Italy
    Italy
    India Macleods Pharma
    Type: Producer
    Produced in: India
    Unknown
    India Gland Pharma
    Type: Producer
    Produced in: India
    India
    China Shandong Octagon Chemicals Limited

    MOQ: 25 kg
    Type: Producer
    Produced in: China
    China
    Japan ACE Japan
    Type: Producer
    Produced in: Japan
    Japan
    Italy Lundbeck Pharma
    Type: Producer
    Produced in: Italy
    Italy
    China CSPC Ouyi Pharma
    Type: Producer
    Produced in: China
    China
    Japan Sogo Pharmaceutical
    Type: Producer
    Produced in: Japan
    Japan
    China Taicang Pharmaceutical Factory
    Type: Producer
    Produced in: China
    China
    France Quimdis
    Type: Distributor
    Produced in: France
    Unknown
    China Shaoxing Hantai Pharma
    Type: Distributor
    Produced in: China
    China

    Looking for Indomethacin 53-86-1?

    API | Excipient name:
    Indomethacin 
    Synonyms:
    Aconip, Indocin, Indometacin, Indometacina, Indometacine, Indometacinum, Indomethacin, Indometacin  
    Cas Number:
    53-86-1 
    DrugBank number:
    DB00328 
    Unique Ingredient Identifier:
    XXE1CET956

    About Indomethacin

    Learn more about Indomethacin. Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood, however, it is thought to be mediated through potent and nonselective inhibition of the enzyme cyclooxygenase (COX), which is the main enzyme responsible for catalyzes the rate-limiting step in prostaglandin and thromboxane biosynthesis via the arachidonic acid (AA) pathway.

    Indometacin was first discovered in 1963 and it was first approved for use in the USA by the Food and Drug Administration in 1965, 10 along with other acetic acid derivatives such as diclofenac and sulindac that were also developed during the 1960s. Since then, indometacin has been extensively studied in clinical trials as one of the most potent NSAIDs in blocking prostaglandin synthesis and was among the first NSAIDs to be used in the symptomatic treatment of migraine and for headaches that eventually became known as “indomethacin-responsive” headache disorders. Most commonly used in rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, acute shoulder pains, and acute gouty arthritis, indometacin is currently available as oral capsules as well as other methods of administration, including rectal and intravenous formulations. Intravenous indometacin is administered to close a hemodynamically significant patent ductus arteriosus, as indicated by clinical evidence, in premature infants.

    Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

    Indomethacin manufacturers | traders | suppliers
    We have 11 companies offering Indomethacin from 5 different countries.

    Get in contact with the supplier of your choice:

    • Shandong Octagon Chemicals Limited from China
    • Gland Pharma from India
    • Fabbrica Italiana Sintetici (FIS) from Italy
    • Shaoxing Hantai Pharma from China
    • Macleods Pharma from India
    • CSPC Ouyi Pharma from China
    • Taicang Pharmaceutical Factory from China
    • Sogo Pharmaceutical from Japan
    • Lundbeck Pharma from Italy
    • ACE Japan from Japan
    • Quimdis from France

    Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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