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Desflurane
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Established in: 1994
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Looking for Desflurane API 57041-67-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Desflurane. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Desflurane
- Synonyms:
- Desflurane , Desflurano , Desfluranum , Suprane
- Cas Number:
- 57041-67-5
- DrugBank number:
- DB01189
- Unique Ingredient Identifier:
- CRS35BZ94Q
About Desflurane
Learn more about Desflurane. Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane1. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic0 Desflurane was granted FDA approval on 18 September 1992.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Desflurane is a type of Inhalation anesthetics
Inhalation anesthetics belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used for inducing general anesthesia. These specialized compounds are administered through inhalation, allowing them to be rapidly absorbed into the bloodstream and exert their anesthetic effects. Inhalation anesthetics are widely utilized in surgical procedures to achieve unconsciousness, analgesia (pain relief), muscle relaxation, and amnesia.
The primary mechanism of action of inhalation anesthetics involves targeting the central nervous system (CNS) and altering neuronal activity. By binding to specific receptors, these anesthetics modulate neurotransmitter release, resulting in the depression of neuronal signaling. This leads to a reversible loss of consciousness and pain sensation, enabling surgeons to perform invasive procedures without causing discomfort or distress to the patient.
Common inhalation anesthetics include volatile liquids such as sevoflurane, desflurane, and isoflurane, as well as nitrous oxide (N2O), which is a gas. These agents possess favorable characteristics, such as rapid onset and offset of action, high potency, and controllable depth of anesthesia. Inhalation anesthetics offer advantages like easy administration, precise dosage titration, and minimal metabolism-related side effects.
The pharmaceutical industry ensures the quality and safety of inhalation anesthetics through rigorous manufacturing processes and strict quality control measures. Stringent regulations are in place to maintain the purity, stability, and efficacy of these APIs. Additionally, continuous research and development efforts aim to improve the pharmacokinetics, safety profiles, and environmental impact of inhalation anesthetics, further enhancing patient care and surgical outcomes.
Desflurane (Inhalation anesthetics), classified under Anesthetics
Anesthetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the field of medicine. These substances play a vital role in inducing a temporary loss of sensation or consciousness, enabling medical procedures to be performed without pain or discomfort. Anesthetics can be classified into two primary types: general anesthetics and local anesthetics.
General anesthetics act on the central nervous system, producing a reversible loss of consciousness. They are administered through inhalation or injection routes and are commonly employed for major surgeries or procedures that require deep sedation. Examples of general anesthetics include sevoflurane, propofol, and isoflurane.
On the other hand, local anesthetics primarily target a specific region or part of the body, temporarily numbing the area and blocking pain signals. These APIs are frequently used in dental procedures, minor surgeries, and childbirth. Common local anesthetics include lidocaine, bupivacaine, and ropivacaine.
Anesthetics work by interfering with the transmission of nerve signals or by altering the activity of certain receptors in the nervous system. They offer precise control over pain management, allowing medical professionals to perform complex procedures with reduced patient discomfort and anxiety.
The development and manufacturing of anesthetics APIs require stringent quality control measures to ensure safety and efficacy. Pharmaceutical companies adhere to strict regulatory guidelines to produce high-quality APIs. The demand for anesthetics remains consistently high, making this category of APIs a critical component of the pharmaceutical industry.
In conclusion, anesthetics are indispensable pharmaceutical APIs used to induce temporary loss of sensation or consciousness. They can be classified into general and local anesthetics, each serving distinct purposes in medical procedures. The proper development and manufacturing of anesthetics APIs are essential to ensure safe and effective pain management in various healthcare settings.
Desflurane manufacturers | traders | suppliers
We have 2 companies offering Desflurane produced in 2 different countries.
Get in contact with the supplier of your choice:
- Rochem International, Inc. from United States, product country of origin United States
- Piramal Pharma Solutions from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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