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Bupivacaine hydrochloride (Bupivacaine) API Manufacturers & Suppliers

Looking for Bupivacaine API 38396-39-3?

Description:

Here you will find a list of producers, manufacturers and distributors of Bupivacaine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Bupivacaine 

Synonyms:

Bupivacaina , Bupivacainum , DL-Bupivacaine , racemic bupivacaine , Bupivacaini , Bupivacaine hydrochloride  

Cas Number:

38396-39-3 

DrugBank number:

DB00297 

Unique Ingredient Identifier:

Y8335394RO

Bupivacaine is a type of Local anesthetics

Local anesthetics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) commonly used to numb a specific area of the body during medical procedures or surgeries. They work by blocking the transmission of nerve signals, preventing the sensation of pain in the targeted region. Local anesthetics are vital for various medical applications, including dental procedures, minor surgeries, and childbirth.

The main mechanism of action for local anesthetics involves the reversible inhibition of sodium channels, which are responsible for the conduction of nerve impulses. By binding to these channels, local anesthetics prevent the influx of sodium ions, which blocks the generation and propagation of nerve signals. This results in temporary loss of sensation in the area where the medication is administered.

Local anesthetics can be categorized into two main types: esters and amides. Esters, such as procaine and benzocaine, are metabolized by plasma esterases, while amides, including lidocaine and bupivacaine, undergo hepatic metabolism. The choice of local anesthetic depends on factors such as the duration of action required, the specific procedure being performed, and the patient's medical history.

It is important to note that local anesthetics should be administered with caution, as they can have potential side effects, including allergic reactions, systemic toxicity, and nerve damage if used improperly. Therefore, proper dosage and administration techniques must be followed to ensure patient safety.

In summary, local anesthetics are essential pharmaceutical APIs used to temporarily block nerve signals, providing localized pain relief during medical procedures. Understanding the different types and their mechanisms of action allows healthcare professionals to select the most appropriate local anesthetic for each patient and procedure, ensuring optimal outcomes and patient comfort.

• Senova Technology Co., Ltd. from China, product country of origin China
• Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
• Shandong Boyuan from China, product country of origin China
• LGM Pharma from United States, product country of origin World
• Shandong Octagon Chemicals Limited from China, product country of origin China
• Gonane Pharma from India, product country of origin India
• Duchefa Farma B.V. from Netherlands, product country of origin Switzerland
• Nortec Química from Brazil, product country of origin Brazil
• Dishman Pharmaceuticals and Chemicals from India, product country of origin Unknown
• S.I.M.S. from Italy, product country of origin Italy
• Medigraph Pharma from India, product country of origin India
• TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
• Asence Pharma from India, product country of origin India
• Siegfried from Germany, product country of origin Switzerland
• Moehs from Spain, product country of origin Spain
• Cambrex, Karlskoga from Sweden, product country of origin Sweden

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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