Lidocaine

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Description:

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API | Excipient name:

Lidocaine 

Synonyms:

Lignocaine , Lidocaini , Lidocainum  

Cas Number:

137-58-6 

DrugBank number:

DB00281 

Unique Ingredient Identifier:

98PI200987

Lidocaine is a type of Local anesthetics

Local anesthetics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) commonly used to numb a specific area of the body during medical procedures or surgeries. They work by blocking the transmission of nerve signals, preventing the sensation of pain in the targeted region. Local anesthetics are vital for various medical applications, including dental procedures, minor surgeries, and childbirth.

The main mechanism of action for local anesthetics involves the reversible inhibition of sodium channels, which are responsible for the conduction of nerve impulses. By binding to these channels, local anesthetics prevent the influx of sodium ions, which blocks the generation and propagation of nerve signals. This results in temporary loss of sensation in the area where the medication is administered.

Local anesthetics can be categorized into two main types: esters and amides. Esters, such as procaine and benzocaine, are metabolized by plasma esterases, while amides, including lidocaine and bupivacaine, undergo hepatic metabolism. The choice of local anesthetic depends on factors such as the duration of action required, the specific procedure being performed, and the patient's medical history.

It is important to note that local anesthetics should be administered with caution, as they can have potential side effects, including allergic reactions, systemic toxicity, and nerve damage if used improperly. Therefore, proper dosage and administration techniques must be followed to ensure patient safety.

In summary, local anesthetics are essential pharmaceutical APIs used to temporarily block nerve signals, providing localized pain relief during medical procedures. Understanding the different types and their mechanisms of action allows healthcare professionals to select the most appropriate local anesthetic for each patient and procedure, ensuring optimal outcomes and patient comfort.

• LGM Pharma from United States
• Fagron Industry from Belgium
• DKSH from Switzerland
• Xi'an Tian Guangyuan Biotech Co.,Ltd from China
• Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China
• Duchefa Farma B.V. from Netherlands
• Shandong Octagon Chemicals Limited from China
• Gonane Pharma from India
• TIEFENBACHER API + Ingredients from Germany
• Caesar & Loretz GmbH (CAELO) from Germany
• Otto Brandes GmbH from Germany
• Albemarle from United States
• Apex Healthcare from India
• Harman Finochem from India
• Iwaki Seiyaku from Japan
• Mahendra Chemicals from India
• S.I.M.S. from Italy
• InventyS Research Company Pvt. Ltd. from India
• Sichuan Benepure from China
• Delta Synthetic from Taiwan
• Gufic Biosciences from India
• Moehs from Spain
• Cambrex, Karlskoga from Sweden

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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