Milnacipran
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Looking for Milnacipran 92623-85-3?
- Description:
- Here you will find a list of producers, manufacturers and traders of Milnacipran. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Milnacipran
- Synonyms:
- Midalcipran , Milnacipran , Milnacipranum
- Cas Number:
- 92623-85-3
- DrugBank number:
- DB04896
- Unique Ingredient Identifier:
- G56VK1HF36
About Milnacipran
More information about this product: Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression 2781. Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of treating fibromyalgia 26, although other regional regulatory authorities like the EMA, among others, have not yet approved the agent for such treatment, citing lack of robust evidence of efficacy, insufficient demonstration of maintenance of effect, and other concerns 278. Nevertheless, milnacipran demonstrates a somewhat unique characteristic among SNRIs to elicit a relatively balanced reuptake inhibition of both serotonin and noradrenaline, with a somewhat increased preference for noradrenaline reuptake inhibition - which is potentially a point of interest given the plausible proposal that noradrenaline plays an important role in the mitigation of pain signals in the descending inhibitory pain pathways in the brain and spinal cord 14. Moreover, recent research has shown that the levorotatory enantiomer of milnacipran, levomilnacipran, may have the capacity to inhibit the activity of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), which has investigationally been associated with β-amyloid plaque formation - making the agent a possible course of treatment for Alzheimer's disease.
You can find more info about this product by clicking on the DB ID above.
Milnacipran manufacturers | traders | suppliers
We have 16 companies offering Milnacipran from 5 different countries.
Get in contact with the supplier of your choice:
- Centaur Pharma from India
- Raks Pharma from India
- Derivados Quimicos from Spain
- Dishman Pharmaceuticals and Chemicals from India
- Pierre Fabre Medi. from France
- Unichem Labs. from India
- Sumitomo Chemical from Japan
- Cosma from Italy
- ACE Japan from Japan
- Lupin from India
- Dr. Reddy's from India
- Hetero Labs from India
- Mylan from India
- Glenmark Pharma from India
- Micro Labs from India
- MSN Pharma from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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