Oxymetazoline API Manufacturers

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Looking for Oxymetazoline API 1491-59-4?

Description:
Here you will find a list of producers, manufacturers and traders of Oxymetazoline. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Oxymetazoline 
Synonyms:
Oximetazolinum , Oxymetazolina , Oxymetazolinum , Oxymethazoline , Oxymetozoline , Oxymetazoline hydrochloride  
Cas Number:
1491-59-4 
DrugBank number:
DB00935 
Unique Ingredient Identifier:
8VLN5B44ZY

About Oxymetazoline

More information about the use of: Oxymetazoline. Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults.

As an effective decongestant, oxymetazoline is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common cold, hay fever, and upper respiratory allergies In dentistry, oxymetazoline and tetracaine combination intranasal spray (Kovanaze) is used for regional anesthesia during dental procedures in children and adults. In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq) in adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment for this medical condition.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Oxymetazoline is a type of Nasal decongestants


Nasal decongestants belong to the pharmaceutical API (Active Pharmaceutical Ingredient) subcategory used for alleviating nasal congestion. They are commonly employed to relieve symptoms associated with various respiratory conditions, including allergies, colds, and sinusitis.

These decongestants work by constricting the blood vessels in the nasal passages, thereby reducing inflammation and swelling. The main mechanism of action involves stimulating alpha-adrenergic receptors, which leads to the narrowing of blood vessels and decreases blood flow to the nasal mucosa.

One of the widely used nasal decongestants is oxymetazoline, available in both over-the-counter and prescription-strength formulations. It exhibits a rapid onset of action and provides long-lasting relief from nasal congestion. Oxymetazoline acts selectively on alpha-adrenergic receptors, ensuring localized effects without significant systemic absorption.

Another common nasal decongestant is phenylephrine, which is often found in over-the-counter nasal sprays and oral formulations. Phenylephrine constricts blood vessels in the nasal passages, promoting nasal decongestion. However, its efficacy may be somewhat limited compared to other nasal decongestants.

Nasal decongestants come in various formulations, including nasal sprays, drops, and oral tablets. It is important to follow the recommended dosage instructions and not exceed the recommended duration of use to avoid potential rebound congestion or other adverse effects.

Before using nasal decongestants, it is advisable to consult a healthcare professional, especially for individuals with certain medical conditions or those taking other medications, to ensure their safe and effective use.

Overall, nasal decongestants play a crucial role in providing temporary relief from nasal congestion and improving breathing comfort for individuals suffering from respiratory ailments.


Oxymetazoline (Nasal decongestants ), classified under Respiratory Tract Agents


Respiratory Tract Agents are a vital category of pharmaceutical APIs (Active Pharmaceutical Ingredients) designed to treat respiratory conditions and diseases. These agents are specifically formulated to target the respiratory system, which includes the lungs, airways, and nasal passages. They play a crucial role in managing various respiratory disorders, such as asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis.

Respiratory Tract Agents encompass a wide range of medications, including bronchodilators, corticosteroids, antihistamines, and mucolytics. Bronchodilators are commonly used to relieve airway constriction and facilitate smooth breathing by relaxing the muscles in the airways. Corticosteroids help reduce inflammation in the respiratory system, alleviating symptoms and preventing exacerbations. Antihistamines work by blocking histamine receptors, thus mitigating allergic reactions that often impact the respiratory tract. Mucolytics aid in loosening and thinning mucus, making it easier to expel from the airways.

These APIs are developed through rigorous research and development processes, ensuring their efficacy, safety, and compliance with regulatory standards. Pharmaceutical manufacturers rely on advanced technologies and stringent quality control measures to produce high-quality Respiratory Tract Agents. These APIs are subsequently incorporated into various dosage forms, including inhalers, nasal sprays, nebulizers, and oral medications.

Respiratory Tract Agents are essential in the management of respiratory conditions, providing relief from symptoms, improving lung function, and enhancing the overall quality of life for patients. They are prescribed by healthcare professionals and often used in combination therapies to achieve optimal results. As respiratory disorders continue to affect a significant portion of the global population, the development and availability of effective Respiratory Tract Agents play a vital role in addressing these health challenges and improving patient outcomes.



Oxymetazoline manufacturers | traders | suppliers

We have 4 companies offering Oxymetazoline produced in 4 different countries.

Get in contact with the supplier of your choice:

  • LGM Pharma from United States, product country of origin World
  • Changzhou Yabang from China, product country of origin China
  • Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
  • Siegfried from Germany, product country of origin Unknown

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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