Diclofenac
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Distributor
Produced in:
Established in: 2005
MOQ: -
Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support
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Distributor
Produced in:
Established in: 1865
MOQ: -
Employees: 33,000+

Valid Regulatory support

Marketing Intelligence to stay on trend and ahead in the market

Tailored value-added services that support the increase of market potential
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Producer
Produced in:
Established in: 2005
MOQ: 1 kg
Employees: 85

Strict quality control

15 years of experience in API production

Provide OEM & ODM service
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Distributor
Produced in:

Established in: 1963
MOQ: -
Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe
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Producer
Produced in:
Established in: 2018
MOQ: -
Employees: 200+

WHO GMP Approved sites for production

25+ years experience in manufacturing APIs for regulated markets

High quality product & superior client service
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Distributor
Produced in:
Established in: 1923
MOQ: 25 kg
Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation
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Looking for Diclofenac 15307-86-5?
- Description:
- Here you will find a list of producers, manufacturers and traders of Diclofenac. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Diclofenac
- Synonyms:
- Diclofenac , Diclofenac Acid , Diclofenaco , Diclofenacum , ISV-205 , Diclofenac sodium
- Cas Number:
- 15307-86-5
- DrugBank number:
- DB00586
- Unique Ingredient Identifier:
- 144O8QL0L1
About Diclofenac
Want to know what Diclofenac is used for? Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.
Diclofenac was the product of rational drug design based on the structures of phenylbutazone, mefenamic acid, and indomethacin. The addition of two chlorine groups in the ortho position of the phenyl ring locks the ring in maximal torsion which appears to be related to increased potency. It is often used in combination with misoprostol to prevent NSAID-induced gastric ulcers. Diclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Diclofenac is a type of NSAIDs
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) are a widely used subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs). These medications are commonly prescribed for their analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) properties. NSAIDs work by inhibiting the production of certain enzymes called cyclooxygenases (COX), which play a crucial role in the synthesis of prostaglandins, substances that contribute to pain, inflammation, and fever.
These pharmaceutical APIs are available in various formulations, including tablets, capsules, creams, and gels, making them convenient for different administration routes. Some popular examples of NSAIDs include aspirin, ibuprofen, naproxen, and diclofenac.
NSAIDs are commonly used to treat a wide range of conditions such as arthritis, musculoskeletal injuries, dental pain, menstrual pain, and headaches. They are also effective in managing inflammatory conditions like rheumatoid arthritis and ankylosing spondylitis.
While NSAIDs are generally safe and effective when used as directed, they may have side effects. These can include gastrointestinal issues such as stomach ulcers or bleeding, cardiovascular risks, and kidney problems. Therefore, it is essential to follow the recommended dosage and consult with healthcare professionals to ensure proper and safe usage.
In conclusion, NSAIDs are a subcategory of pharmaceutical APIs that offer analgesic, anti-inflammatory, and antipyretic properties. Their versatility and effectiveness in treating various conditions make them widely prescribed medications. However, it is crucial to be aware of potential side effects and consult healthcare providers for appropriate usage.
Diclofenac (NSAIDs), classified under Anti-inflammatory Agents
Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.
Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.
Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.
In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.
Diclofenac manufacturers | traders | suppliers
We have 29 companies offering Diclofenac from 8 different countries.
Get in contact with the supplier of your choice:
- LGM Pharma from United States
- DKSH from Switzerland
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China
- TIEFENBACHER API + Ingredients from Germany
- Gonane Pharma from India
- Otto Brandes GmbH from Germany
- G.C. Chemie Pharmie Ltd from India
- Liaoyuan City Baikang from China
- Amsa S.P.A. from Italy
- Ningbo Smart from China
- Amoli Organics from India
- Henan Dongtai Pharm from China
- Murli Krishna Pharma Pvt. Ltd from India
- Arch Pharmalabs from India
- Cheng Fong Chemical from Taiwan
- Corden Pharma from Germany
- Unique Chemicals from India
- Yung Zip Chemical from Taiwan
- Hachidai Pharmaceutical from Japan
- Jiwan Pharmaceutical Technology Co.,Ltd from China
- Syn-tech Chem from Taiwan
- Cosma from Italy
- Unnati Pharmaceuticals Pvt Ltd from India
- Aarambh Life Science from India
- Quimdis from France
- Chemizo Enterprise from India
- Dipharma Francis S.r.l. from Italy
- Hetero Drugs from India
- Shaoxing Hantai Pharma from China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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