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TOP RANKING

Located in:

China

Produced in:

China

Established in: 2007

MOQ: -

Employees: 200+

GMP, WC, CEP, FDA, ISO Certificate

Arshine Group supplies more than 2,000 kinds of products

Arshine's marketing network has spread over more than 100 countries

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TOP RANKING

Located in:

United States

Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2005

MOQ: 1 kg

Employees: 85

Strict quality control

15 years of experience in API production

Provide OEM & ODM service

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

India

Established in: 2018

MOQ: -

Employees: 200+

WHO GMP Approved sites for production

25+ years experience in manufacturing APIs for regulated markets

High quality product & superior client service

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Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Produced in:

India

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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Located in:

Italy

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India
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China
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India
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France

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India
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Looking for Diclofenac API 15307-86-5?

Description:
Here you will find a list of producers, manufacturers and traders of Diclofenac. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Diclofenac 
Synonyms:
Diclofenac , Diclofenac Acid , Diclofenaco , Diclofenacum , ISV-205 , Diclofenac sodium  
Cas Number:
15307-86-5 
DrugBank number:
DB00586 
Unique Ingredient Identifier:
144O8QL0L1

About Diclofenac

Want to know what Diclofenac is used for? Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.

Diclofenac was the product of rational drug design based on the structures of phenylbutazone, mefenamic acid, and indomethacin. The addition of two chlorine groups in the ortho position of the phenyl ring locks the ring in maximal torsion which appears to be related to increased potency. It is often used in combination with misoprostol to prevent NSAID-induced gastric ulcers. Diclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).

Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.

Diclofenac is a type of NSAIDs


NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) are a widely used subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs). These medications are commonly prescribed for their analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) properties. NSAIDs work by inhibiting the production of certain enzymes called cyclooxygenases (COX), which play a crucial role in the synthesis of prostaglandins, substances that contribute to pain, inflammation, and fever.

These pharmaceutical APIs are available in various formulations, including tablets, capsules, creams, and gels, making them convenient for different administration routes. Some popular examples of NSAIDs include aspirin, ibuprofen, naproxen, and diclofenac.

NSAIDs are commonly used to treat a wide range of conditions such as arthritis, musculoskeletal injuries, dental pain, menstrual pain, and headaches. They are also effective in managing inflammatory conditions like rheumatoid arthritis and ankylosing spondylitis.

While NSAIDs are generally safe and effective when used as directed, they may have side effects. These can include gastrointestinal issues such as stomach ulcers or bleeding, cardiovascular risks, and kidney problems. Therefore, it is essential to follow the recommended dosage and consult with healthcare professionals to ensure proper and safe usage.

In conclusion, NSAIDs are a subcategory of pharmaceutical APIs that offer analgesic, anti-inflammatory, and antipyretic properties. Their versatility and effectiveness in treating various conditions make them widely prescribed medications. However, it is crucial to be aware of potential side effects and consult healthcare providers for appropriate usage.


Diclofenac (NSAIDs), classified under Anti-inflammatory Agents


Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.

Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.

Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.

In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.



Diclofenac manufacturers | traders | suppliers

We have 30 companies offering Diclofenac produced in 7 different countries.

Get in contact with the supplier of your choice:

  • Arshine Pharmaceutical Co., Limited from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Gonane Pharma from India, product country of origin India
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Otto Brandes GmbH from Germany, product country of origin India
  • Cosma from Italy, product country of origin Italy
  • G.C. Chemie Pharmie Ltd from India, product country of origin India
  • Jiwan Pharmaceutical Technology Co.,Ltd from China, product country of origin China
  • Unique Chemicals from India, product country of origin India
  • Henan Dongtai Pharm from China, product country of origin China
  • Murli Krishna Pharma Pvt. Ltd from India, product country of origin India
  • Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
  • Liaoyuan City Baikang from China, product country of origin China
  • Syn-tech Chem from Taiwan, product country of origin Taiwan
  • Quimdis from France, product country of origin Unknown
  • Aarambh Life Science from India, product country of origin India
  • Amsa S.P.A. from Italy, product country of origin Italy
  • Ningbo Smart from China, product country of origin China
  • Amoli Organics from India, product country of origin India
  • Yung Zip Chemical from Taiwan, product country of origin Taiwan
  • Hachidai Pharmaceutical from Japan, product country of origin Japan
  • Cheng Fong Chemical from Taiwan, product country of origin Taiwan
  • Corden Pharma from Germany, product country of origin Italy
  • Arch Pharmalabs from India, product country of origin India
  • Dipharma Francis S.r.l. from Italy, product country of origin Italy
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Hetero Drugs from India, product country of origin India
  • Chemizo Enterprise from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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