Naloxone API Manufacturers

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TOP RANKING

Located in:

Denmark

Produced in:

Denmark

Established in: 1885

MOQ: -

Employees: 150

Trusted for 140 years

Global distribution business with API manufacturing facilities

European company with presence in 3 continents

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

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  • GMP

  • CoA

  • MSDS

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TOP RANKING

Located in:

United States

Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CEP

  • GMP

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  • BSE/TSE

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TOP RANKING

Located in:

Iran

Producer

Produced in:

Iran

Established in: 1997

MOQ: -

Employees: 500+

Exports 25 products to 52 countries in 5 continents

21 active production lines of GMP standards

Specialized in Narcotic and Non-Narcotic APIs, FDFs and Intermediates

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • GMP

  • ISO9001

  • WC

  • DMF

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HIGHLIGHTED

Located in:

Turkey

Producer

Produced in:

Turkey

Established in: 2022

MOQ: -

Employees: 100+

Operating on GMP guidelines with the most recent technologies and equipment

High-quality products at unrivaled prices

Specialize in Narcotic and Non-Narcotic APIs

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • WC

  • GMP

  • CoA

  • MSDS

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • MSDS

  • GMP

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Located in:

United Kingdom

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • DMF

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  • FDA

  • CEP

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Replies slower than most

Located in:

Italy

Produced in:

Italy

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • GMP

  • coa

  • FDA

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Replies slower than most

Located in:

United States

Producer

Produced in:

United States

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Replies slower than most

Located in:

United States

Produced in:

United States

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • GMP

  • FDA

  • CEP

  • coa

Located in:

India
  • CoA

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  • GMP

  • WHO-GMP

  • CoA

Located in:

Germany

Producer

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • FDA

  • DMF

  • CEP

  • GMP

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • WC

  • CoA

  • GMP

  • DMF

Located in:

France

Producer

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • KDMF

  • DMF

  • JDMF

  • GMP

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  • FDA

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Looking for Naloxone API 465-65-6?

Description:
Here you will find a list of producers, manufacturers and distributors of Naloxone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Naloxone 
Synonyms:
EN 1530 Base , L-Naloxone , N-Allylnoroxymorphone , Nalossone , Naloxona , Naloxone , Naloxonum , Naloxone hydrochloride dihydrate  
Cas Number:
465-65-6 
DrugBank number:
DB01183 
Unique Ingredient Identifier:
36B82AMQ7N

About Naloxone

Some technical information about this product: Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors. When taken in large quantities, opioid medications such as morphine, hydromorphone, methadone, heroin, or fentanyl are capable of causing life-threatening symptoms such as respiratory depression, reduced heart rate, slurred speech, drowsiness, and constricted pupils. If untreated, this can progress to vomiting, absent pulse and breathing, loss of consciousness, and even death.

Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression in opioid overdose. It's important to note that naloxone only works on opioid receptors within the body, and is therefore not capable of reversing the effects of non-opioid medications such as stimulants like methamphetamine or cocaine, or benzodiazepines like lorazepam or diazepam. Also known as the brand name product Narcan, naloxone is currently available by intramuscular (IM) or subcutaneous (SubQ) injection, nasal spray, or intravenous (IV) infusion. Naloxone IM injections are commonly available in the form of "kits", which is ideal for making overdose treatment accessible and readily available for administration by minimally trained individuals within the community. Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. Frequently also carried by medical and emergency personnel and at events known to be associated with heavy drug use like music festivals, naloxone kits are considered a key component of harm reduction strategies.

You can ask the supplier for more technical information about the product.

Naloxone is a type of Opioid antagonists


Opioid antagonists are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in the management and treatment of opioid-related disorders. These powerful substances bind to opioid receptors in the brain, blocking the effects of opioids and reversing their potentially life-threatening effects.

Opioid antagonists work by competitively binding to opioid receptors, preventing opioids from attaching to these receptors and inhibiting their activity. This mechanism of action effectively counteracts the effects of opioids, including pain relief, sedation, and respiratory depression. By blocking the receptors, opioid antagonists can rapidly reverse the effects of opioid overdose, providing a vital emergency intervention.

One of the widely used opioid antagonists is naloxone, a highly effective and fast-acting medication. Naloxone is commonly administered in emergency settings, such as hospitals and ambulances, as well as by first responders and bystanders. Its rapid onset of action and short duration make it an essential tool for reversing opioid overdoses, potentially saving lives.

Opioid antagonists not only serve as a critical intervention for overdose cases but also have applications in the management of opioid addiction. By blocking the rewarding effects of opioids, these pharmaceutical APIs can help reduce cravings and prevent relapse in individuals undergoing opioid dependence treatment.

In conclusion, opioid antagonists are indispensable pharmaceutical APIs in combating the devastating effects of opioids. Their ability to bind to opioid receptors and counteract the effects of opioids makes them essential in both emergency situations and addiction treatment. Naloxone, among other opioid antagonists, stands as a crucial tool in saving lives and addressing the opioid crisis.

Naloxone manufacturers | traders | suppliers

We have 13 companies offering Naloxone produced in 8 different countries.

Get in contact with the supplier of your choice:

  • Chr. Olesen Group from Denmark, product country of origin Denmark
  • LGM Pharma from United States, product country of origin World
  • Temad Co. from Iran, product country of origin Iran
  • PluviaEndo from Turkey, product country of origin Turkey
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Macfarlan Smith from United Kingdom, product country of origin Unknown
  • S.A.L.A.R.S. from Italy, product country of origin Italy
  • Noramco from United States, product country of origin United States
  • Mallinckrodt from United States, product country of origin United States
  • Resonance Labs. from India, product country of origin India
  • Siegfried from Germany, product country of origin Unknown
  • Sun Pharma from India, product country of origin India
  • Sanofi from France, product country of origin Unknown

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

You can use the filters to find high-quality suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our FAQ page or use the chat box in the corner to get more information about Pharmaoffer.