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Pembrolizumab
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Established in: 2005
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Looking for Pembrolizumab API 1374853-91-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pembrolizumab. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pembrolizumab
- Cas Number:
- 1374853-91-4
- DrugBank number:
- DB09037
- Unique Ingredient Identifier:
- DPT0O3T46P
About Pembrolizumab
Here is a short description about Pembrolizumab. Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptor. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype with the containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds.
It was developed by Merck & Co and firstly approved for the treatment of metastatic malignant melanoma. This is the first approved therapy against PD-1. It was approved firstly by the FDA on September 2014. Its approval in melanoma was extended to several countries such as Australia, Israel, Korea, Macau, the European Union and the United Arab Emirates. On June 2018, Pembrolizumab was approved for the treatment of cervical cancer under the status of accelerated approval.
You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.
Pembrolizumab manufacturers | traders | suppliers
We have 1 companies offering Pembrolizumab produced in 1 different countries.
Get in contact with the supplier of your choice:
- LGM Pharma from United States, product country of origin World
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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