Riociguat API Manufacturers & Suppliers
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Produced in:
Established in: 2004
MOQ: -
Employees: 700+
has international standard facilities for API
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has 3 manufacturing plants
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Producer
Produced in:
Established in: 2013
MOQ: 1 g
Employees: 25+
ISO9001 certified
Drug R&D center (in Hangzhou)
From lab scale (mg/g) to commercial scale (kgs/tons)
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Established in: 2005
MOQ: -
Employees: 200+
Portfolio of over 2,000 APIs
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Looking for Riociguat API 625115-55-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Riociguat. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Riociguat
- Cas Number:
- 625115-55-1
- DrugBank number:
- DB08931
- Unique Ingredient Identifier:
- RU3FE2Y4XI
About Riociguat
What can you use it for? Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III;and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO FC II or III. Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $700 for 30 days of treatment.
You can find more info about this product by clicking on the DB ID above.
Riociguat is a type of sGC stimulator
The sGC stimulator is a pharmaceutical API (Active Pharmaceutical Ingredient) that falls under the subcategory of soluble guanylate cyclase stimulators. It is an innovative therapeutic agent that has gained significant attention in the field of cardiovascular medicine.
sGC stands for soluble guanylate cyclase, which is an enzyme found in various tissues throughout the body, including blood vessels and the heart. This enzyme plays a crucial role in regulating the production of cyclic guanosine monophosphate (cGMP), a signaling molecule involved in smooth muscle relaxation and vasodilation.
sGC stimulators work by directly activating the sGC enzyme, leading to increased production of cGMP. This, in turn, promotes relaxation of smooth muscles in blood vessels, resulting in vasodilation and improved blood flow. By enhancing the activity of sGC, these stimulators provide a unique mechanism of action for treating cardiovascular diseases, such as pulmonary hypertension and heart failure.
Pharmaceutical companies have been actively researching and developing sGC stimulators as potential therapeutic options. These APIs offer promising benefits, including improved exercise capacity, reduced symptoms, and enhanced quality of life for patients with cardiovascular conditions.
As the pharmaceutical industry continues to advance, sGC stimulators hold great promise for the treatment of various cardiovascular disorders. Their targeted mechanism of action and potential positive impact on patient outcomes make them a valuable addition to the arsenal of medications available to healthcare professionals.
Riociguat (sGC stimulator), classified under Antihypertensive agents
Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.
Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.
ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.
Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.
Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.
In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.
Riociguat manufacturers | traders | suppliers
We have 5 companies offering Riociguat produced in 1 different countries.
Get in contact with the supplier of your choice:
- Zhejiang Hengkang Pharmaceutical Co. Ltd from China, product country of origin China
- Senova Technology Co., Ltd. from China, product country of origin China
- LGM Pharma from United States, product country of origin World
- MSN Life Sciences from India, product country of origin India
- Bayer from Germany, product country of origin Germany
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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