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Bazedoxifene
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Distributor
Produced in:
Established in: 2005
MOQ: -
Employees: 200+
Portfolio of over 2,000 APIs
Precise quality control
End-to-end global regulatory support
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Producer
Produced in:
Established in: 2006
MOQ: 1 kg
Employees: 50+
Backward integration with key APIs
Current Good Manufacturing Practices (cGMP)
Unique reaction capabilities
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Looking for Bazedoxifene API 198481-32-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Bazedoxifene. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Bazedoxifene
- Cas Number:
- 198481-32-2
- DrugBank number:
- DB06401
- Unique Ingredient Identifier:
- Q16TT9C5BK
About Bazedoxifene
Do you want to know more about Bazedoxifene? You can find a small explanation about it here. Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy.
In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the FDA for the treatment of moderate to severe vasomotor symptoms associated with menopause, as well as the prevention of postmenopausal osteoporosis in women.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Bazedoxifene is a type of Selective estrogen receptor modulators (SERMs)
Selective estrogen receptor modulators (SERMs) belong to a category of pharmaceutical active ingredients (APIs) that interact with estrogen receptors in a selective manner. SERMs are designed to exert distinct effects on specific tissues by binding to estrogen receptors, which are found in various parts of the body. These compounds exhibit both estrogenic and anti-estrogenic properties, depending on the target tissue.
One of the key applications of SERMs is in the treatment of hormone-related conditions such as breast cancer, osteoporosis, and menopausal symptoms. They function by selectively binding to estrogen receptors in breast tissue, thereby inhibiting the growth-promoting effects of estrogen and reducing the risk of breast cancer. In the case of osteoporosis, SERMs stimulate bone formation and help maintain bone density.
Moreover, SERMs have shown efficacy in managing menopausal symptoms such as hot flashes, vaginal dryness, and mood swings. By binding to estrogen receptors in the brain, they alleviate these symptoms without stimulating the growth of estrogen-dependent tissues like the uterus.
Some commonly known SERMs include tamoxifen, raloxifene, and ospemifene. These compounds have undergone rigorous clinical trials and have been approved by regulatory authorities for specific indications.
In summary, SERMs are a class of pharmaceutical APIs that selectively interact with estrogen receptors, exerting estrogenic or anti-estrogenic effects depending on the target tissue. They have proven to be valuable therapeutic agents in the management of breast cancer, osteoporosis, and menopausal symptoms.
Bazedoxifene manufacturers | traders | suppliers
We have 4 companies offering Bazedoxifene produced in 3 different countries.
Get in contact with the supplier of your choice:
- LGM Pharma from United States, product country of origin World
- Kolon Life Science from South Korea, product country of origin South Korea
- Acura Labs from India, product country of origin India
- MSN Labs. from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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