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Disulfiram
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Produced in:
Established in: 1951
MOQ: -
Employees: 455+
Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.
FDA approved european manufcaturing facilities
Export APIs to more than 60 countries worldwide
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Looking for Disulfiram API 97-77-8?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Disulfiram. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Disulfiram
- Synonyms:
- Antabuse (tn) , Bis(diethylthiocarbamoyl) disulfide , Disulfiram , Tetraethylthiuram Disulfide , Tetraethylthiuram Disulphide
- Cas Number:
- 97-77-8
- DrugBank number:
- DB00822
- Unique Ingredient Identifier:
- TR3MLJ1UAI
About Disulfiram
More information about this product: A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
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Disulfiram is a type of Substances for alcohol addiction
Pharmaceutical API Subcategory: Substances for Alcohol AddictionSubstances for alcohol addiction are a vital subcategory within the pharmaceutical active pharmaceutical ingredients (APIs) market. These substances play a crucial role in the development of medications and therapies designed to address alcohol addiction, a prevalent and serious health issue worldwide.
APIs for alcohol addiction typically consist of specific chemical compounds that target the neurochemical pathways involved in addiction. These substances act on the central nervous system to modulate brain functions, reducing cravings and withdrawal symptoms associated with alcohol dependence.
Common API substances utilized in the treatment of alcohol addiction include naltrexone, acamprosate, and disulfiram. Naltrexone acts by blocking the brain's opioid receptors, thereby decreasing the pleasurable effects of alcohol consumption and reducing cravings. Acamprosate works by stabilizing the chemical balance in the brain, reducing the distressing symptoms experienced during alcohol withdrawal. Disulfiram, on the other hand, creates an unpleasant reaction when alcohol is consumed, acting as a deterrent for individuals trying to abstain from alcohol.
Pharmaceutical companies and research organizations are continuously exploring innovative API substances and formulations to improve the effectiveness and tolerability of alcohol addiction treatments. The development of new substances often involves rigorous clinical trials to ensure their safety and efficacy.
The market for substances targeting alcohol addiction is driven by the increasing awareness of the detrimental effects of excessive alcohol consumption and the growing demand for effective treatment options. By providing pharmaceutical APIs tailored to this subcategory, manufacturers contribute to combating alcohol addiction and supporting individuals on their journey towards recovery.
Disulfiram (Substances for alcohol addiction), classified under Anti-addiction agents
Anti-addiction agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment and management of various forms of addiction. These agents target the neurochemical pathways in the brain that are involved in addiction and dependence, offering therapeutic interventions to individuals struggling with substance abuse disorders.
One prominent group of anti-addiction agents includes opioid receptor antagonists, such as naltrexone and naloxone. These APIs bind to opioid receptors in the brain, blocking the euphoric effects of opioids and reducing cravings. By doing so, they help individuals overcome opioid addiction and prevent relapse.
Another essential class of anti-addiction agents are nicotine receptor agonists, like varenicline. These APIs target nicotine receptors in the brain, reducing the pleasurable sensations associated with smoking and alleviating nicotine withdrawal symptoms. This aids in smoking cessation efforts and enhances long-term abstinence rates.
Furthermore, anti-addiction agents may also encompass APIs used in the treatment of alcohol addiction, such as disulfiram and acamprosate. Disulfiram inhibits the breakdown of alcohol in the body, leading to unpleasant reactions when alcohol is consumed, thus discouraging its use. Acamprosate, on the other hand, helps normalize brain activity disrupted by chronic alcohol use, reducing cravings and promoting abstinence.
In conclusion, anti-addiction agents are a critical category of pharmaceutical APIs used to combat addiction and substance abuse disorders. By targeting specific neurochemical pathways, these agents provide valuable support in overcoming addiction, preventing relapse, and improving the overall well-being of individuals affected by substance abuse.
Disulfiram manufacturers | traders | suppliers
We have 4 companies offering Disulfiram produced in 4 different countries.
Get in contact with the supplier of your choice:
- Polpharma from Poland, product country of origin Poland
- PCI SYNTHESIS from Unknown, product country of origin Unknown
- Productos Aditivos SA from Spain, product country of origin Spain
- Corden Pharma from Germany, product country of origin Italy
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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