Tacrolimus
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Established in: 2019
MOQ: 1 g
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Looking for Tacrolimus 104987-11-3?
- API | Excipient name:
- Tacrolimus
- Synonyms:
- Anhydrous tacrolimus , Tacrolimus anhydrous , Tacrolimus , anhydrous
- Cas Number:
- 104987-11-3
- DrugBank number:
- DB00864
- Unique Ingredient Identifier:
- Y5L2157C4J
About Tacrolimus
Want to know more about Tacrolimus? Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide.
It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription.
Check who is selling Tacrolimus in the overview above.
Tacrolimus manufacturers | traders | suppliers
We have 20 companies offering Tacrolimus from 6 different countries.
Get in contact with the supplier of your choice:
- Apino Pharma Co., Ltd. from China
- Shandong Octagon Chemicals Limited from China
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China
- SENOVA Technology Co., Ltd. from China
- TIEFENBACHER API + Ingredients from Germany
- Duchefa Farma B.V. from Netherlands
- Kromozome from India
- Fujian Kerui from China
- Hangzhou Zhongmei Huadong from China
- Euticals from Italy
- Astellas Pharma from Japan
- Stilbene Biopharma from India
- CKD Bio from South Korea
- Flavine from Germany
- Biocon from India
- Murli Krishna Pharma Pvt. Ltd from India
- Lek Pharma from Slovenia
- Teva API (Czech) from Czech Republic
- Teva API from Israel
- Shaoxing Hantai Pharma from China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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