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Looking for Doxofylline API 69975-86-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Doxofylline. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Doxofylline
- Synonyms:
- Doxophylline
- Cas Number:
- 69975-86-6
- DrugBank number:
- DB09273
- Unique Ingredient Identifier:
- MPM23GMO7Z
About Doxofylline
Some technical information about this product: Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 receptors and lacks stimulating effects. Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug The anti-asthmatic effects of doxophylline are mediated by other mechanisms, primarily through inhibiting the activities of the phosphodiesterase (PDE) enzyme.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Doxofylline is a type of Xanthine derivates
Xanthine derivatives are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a significant role in the development of various medications. Xanthine derivatives are chemical compounds derived from xanthine, a purine base found in various biological systems.
These derivatives possess pharmacological properties that make them valuable for the treatment of numerous medical conditions. The most notable xanthine derivative is caffeine, a widely consumed psychoactive substance with stimulant effects on the central nervous system. Caffeine is commonly found in coffee, tea, and certain soft drinks.
Apart from caffeine, other xanthine derivatives, such as theophylline and theobromine, also exhibit distinct therapeutic properties. Theophylline is utilized for the treatment of respiratory disorders, including asthma and chronic obstructive pulmonary disease (COPD). It functions by relaxing the smooth muscles in the airways, thereby facilitating easier breathing. Theobromine, on the other hand, is found in cocoa products and is known for its mild diuretic effects.
Xanthine derivatives exert their pharmacological effects by competitively inhibiting the action of enzymes called phosphodiesterases. This inhibition leads to increased levels of cyclic adenosine monophosphate (cAMP), resulting in various physiological responses, including bronchodilation and increased heart rate.
In conclusion, xanthine derivatives, including caffeine, theophylline, and theobromine, are essential pharmaceutical ingredients with diverse applications in the medical field. Their unique properties and mechanisms of action make them valuable components in medications for respiratory disorders, cardiovascular conditions, and other therapeutic purposes.
Doxofylline (Xanthine derivates), classified under Respiratory Tract Agents
Respiratory Tract Agents are a vital category of pharmaceutical APIs (Active Pharmaceutical Ingredients) designed to treat respiratory conditions and diseases. These agents are specifically formulated to target the respiratory system, which includes the lungs, airways, and nasal passages. They play a crucial role in managing various respiratory disorders, such as asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis.
Respiratory Tract Agents encompass a wide range of medications, including bronchodilators, corticosteroids, antihistamines, and mucolytics. Bronchodilators are commonly used to relieve airway constriction and facilitate smooth breathing by relaxing the muscles in the airways. Corticosteroids help reduce inflammation in the respiratory system, alleviating symptoms and preventing exacerbations. Antihistamines work by blocking histamine receptors, thus mitigating allergic reactions that often impact the respiratory tract. Mucolytics aid in loosening and thinning mucus, making it easier to expel from the airways.
These APIs are developed through rigorous research and development processes, ensuring their efficacy, safety, and compliance with regulatory standards. Pharmaceutical manufacturers rely on advanced technologies and stringent quality control measures to produce high-quality Respiratory Tract Agents. These APIs are subsequently incorporated into various dosage forms, including inhalers, nasal sprays, nebulizers, and oral medications.
Respiratory Tract Agents are essential in the management of respiratory conditions, providing relief from symptoms, improving lung function, and enhancing the overall quality of life for patients. They are prescribed by healthcare professionals and often used in combination therapies to achieve optimal results. As respiratory disorders continue to affect a significant portion of the global population, the development and availability of effective Respiratory Tract Agents play a vital role in addressing these health challenges and improving patient outcomes.
Doxofylline manufacturers | traders | suppliers
We have 6 companies offering Doxofylline produced in 3 different countries.
Get in contact with the supplier of your choice:
- Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
- ABC Farmaceutici from Italy, product country of origin Italy
- Bakul Pharma from India, product country of origin India
- Zhejiang Changming from China, product country of origin China
- Humble Healthcaare from India, product country of origin India
- Aquatic Remedies Pvt Ltd from India, product country of origin India
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