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Produced in:

China

Established in: 2011

MOQ: 1 kg

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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  • + 0

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Replies can take a few days

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Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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Produced in:

China

Established in: 1968

MOQ: 50 g

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

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Produced in:

China

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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Located in:

India

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Located in:

China

Produced in:

China

MOQ: -

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Located in:

India

Produced in:

India

MOQ: -

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Located in:

United States

Produced in:

Norway

MOQ: -

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Located in:

China

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Produced in:

Unknown

MOQ: -

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Located in:

China

Produced in:

China

MOQ: -

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Located in:

South Korea
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Located in:

Malta

Produced in:

Malta

MOQ: -

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Located in:

China

Produced in:

China

MOQ: 10 kg

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Located in:

China

Produced in:

China

MOQ: -

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Located in:

Taiwan

Produced in:

Taiwan

MOQ: -

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Located in:

China
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Located in:

India

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Produced in:

India

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Located in:

India

Producer

Produced in:

India

MOQ: -

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Looking for Granisetron API 109889-09-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Granisetron. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Granisetron 
Synonyms:
granisetronum , Granisetroni , Granisetron hydrochloride  
Cas Number:
109889-09-0 
DrugBank number:
DB00889 
Unique Ingredient Identifier:
WZG3J2MCOL

About Granisetron

Here you will find more information about Granisetron. A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.

Check who is selling Granisetron in the overview above.

Granisetron is a type of 5HT3 antagonists


5HT3 antagonists are a subcategory of pharmaceutical APIs that play a crucial role in managing various conditions related to the serotonin neurotransmitter system. Serotonin, also known as 5-hydroxytryptamine (5HT), is a neurotransmitter that regulates various physiological functions, including mood, appetite, and gastrointestinal motility.

The 5HT3 antagonists work by selectively blocking the serotonin type 3 receptors in the central and peripheral nervous systems. By doing so, they inhibit the binding of serotonin to these receptors, thereby reducing its effects. This mechanism of action makes them effective in treating conditions such as chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, and irritable bowel syndrome.

One of the commonly used 5HT3 antagonists is ondansetron, which is available in oral and injectable forms. It is widely prescribed to cancer patients undergoing chemotherapy to alleviate the distressing side effects of nausea and vomiting. Other notable 5HT3 antagonists include granisetron, palonosetron, and dolasetron.

These pharmaceutical APIs offer several advantages, including high selectivity for the 5HT3 receptors, rapid onset of action, and a favorable safety profile. They are typically well-tolerated by patients, with minimal adverse effects. However, healthcare professionals must consider individual patient factors and potential drug interactions when prescribing these medications.

In summary, 5HT3 antagonists are an important subcategory of pharmaceutical APIs that provide effective relief from nausea and vomiting associated with various medical conditions. Their targeted mechanism of action and favorable safety profile make them valuable tools in the management of these symptoms, benefiting patients and improving their overall quality of life.


Granisetron (5HT3 antagonists), classified under Antiemetics


Antiemetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate and prevent nausea and vomiting, also known as emesis. They play a vital role in managing these distressing symptoms, which can be caused by various factors such as chemotherapy, postoperative recovery, motion sickness, or gastrointestinal disorders.

Antiemetics work by targeting specific pathways in the body that trigger emesis. One common mechanism involves blocking dopamine receptors in the brain, as dopamine plays a significant role in triggering the vomiting reflex. This class of antiemetics is known as dopamine antagonists. Another mechanism involves inhibiting serotonin receptors, which are associated with nausea and vomiting. These agents, called serotonin antagonists, effectively reduce these symptoms.

In addition to dopamine and serotonin antagonists, other types of antiemetics include neurokinin-1 receptor antagonists, antihistamines, and anticholinergics. Each of these classes acts on different pathways in the body to provide relief from nausea and vomiting.

Pharmaceutical companies manufacture antiemetic APIs in accordance with strict quality control guidelines and regulations. These APIs serve as the active ingredients in various formulations, such as tablets, capsules, injections, or suppositories, designed to deliver the desired therapeutic effects.

Overall, antiemetic APIs form an essential category in the pharmaceutical industry, addressing the significant need for effective management of nausea and vomiting. Their development and availability greatly contribute to enhancing patient comfort and quality of life during various medical treatments and conditions.



Granisetron manufacturers | traders | suppliers

We have 18 companies offering Granisetron produced in 8 different countries.

Get in contact with the supplier of your choice:

  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Duchefa Farma B.V. from Netherlands, product country of origin China
  • Otto Brandes GmbH from Germany, product country of origin China
  • Vihita Chem from India, product country of origin India
  • Hubei Haosun Pharma from China, product country of origin China
  • Natco Pharma from India, product country of origin India
  • Dupont Nutrition from United States, product country of origin Norway
  • Qilu Pharma from China, product country of origin Unknown
  • Zhejiang Hisun Pharma from China, product country of origin China
  • Hana Pharmaceutical from South Korea, product country of origin South Korea
  • Amino Chemicals from Malta, product country of origin Malta
  • Hubei Biocause from China, product country of origin China
  • Chongqing Carelife from China, product country of origin China
  • Syn-tech Chem from Taiwan, product country of origin Taiwan
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Sun Pharma from India, product country of origin India
  • Cipla from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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