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Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
---|---|---|---|---|---|---|---|---|
30-Sep-2024 | (Hidden) | India | JS BANK LT... | Pakistan | PHARMACEUT... | 5 | $ @36$-7! | Check all data |
30-Sep-2024 | (Hidden) | India | GUANG ZHOU... | China | (PROD CODE... | 10 | $ @36$-7! | |
28-Sep-2024 | (Hidden) | India | ATCO LABOR... | Pakistan | PHARMACEUT... | 10 | $ @36$-7! |
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Producer
Produced in:
Established in: 2018
MOQ: -
Employees: 200+
WHO GMP Approved sites for production
25+ years experience in manufacturing APIs for regulated markets
High quality product & superior client service
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Produced in:
Established in: 2004
MOQ: 1 kg
Employees: 3000
NO.2 Huangyang Road,
Yubei District, Chongqing
401120, P.R.China
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Distributor
Produced in:
Established in: 2011
MOQ: 10 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
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Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Produced in:
Established in: 1984
MOQ: -
Employees: 21,650
Diverse portfolio of 180+APIs
1754+ DMF across global markets
1100+ patents filed, and more than 70 own patents granted
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Looking for Ondansetron API 99614-02-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Ondansetron. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Ondansetron
- Synonyms:
- Zofran odt , Ondansetron hydrochloride dihydrate
- Cas Number:
- 99614-02-5
- DrugBank number:
- DB00904
- Unique Ingredient Identifier:
- 4AF302ESOS
About Ondansetron
What can you use it for? A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GSK and approved by the US FDA since January 1991, ondansetron has demonstrated a long history of use and efficacy. Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available as generic products as well, ondansetron continues to see contemporary innovations in its formulation and use, including the development of orally soluble films that are both discreet in administration and less of a burden in comparison to having patients attempt to swallow pills during emesis.
Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.
Ondansetron is a type of 5HT3 antagonists
5HT3 antagonists are a subcategory of pharmaceutical APIs that play a crucial role in managing various conditions related to the serotonin neurotransmitter system. Serotonin, also known as 5-hydroxytryptamine (5HT), is a neurotransmitter that regulates various physiological functions, including mood, appetite, and gastrointestinal motility.
The 5HT3 antagonists work by selectively blocking the serotonin type 3 receptors in the central and peripheral nervous systems. By doing so, they inhibit the binding of serotonin to these receptors, thereby reducing its effects. This mechanism of action makes them effective in treating conditions such as chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, and irritable bowel syndrome.
One of the commonly used 5HT3 antagonists is ondansetron, which is available in oral and injectable forms. It is widely prescribed to cancer patients undergoing chemotherapy to alleviate the distressing side effects of nausea and vomiting. Other notable 5HT3 antagonists include granisetron, palonosetron, and dolasetron.
These pharmaceutical APIs offer several advantages, including high selectivity for the 5HT3 receptors, rapid onset of action, and a favorable safety profile. They are typically well-tolerated by patients, with minimal adverse effects. However, healthcare professionals must consider individual patient factors and potential drug interactions when prescribing these medications.
In summary, 5HT3 antagonists are an important subcategory of pharmaceutical APIs that provide effective relief from nausea and vomiting associated with various medical conditions. Their targeted mechanism of action and favorable safety profile make them valuable tools in the management of these symptoms, benefiting patients and improving their overall quality of life.
Ondansetron (5HT3 antagonists), classified under Antiemetics
Antiemetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate and prevent nausea and vomiting, also known as emesis. They play a vital role in managing these distressing symptoms, which can be caused by various factors such as chemotherapy, postoperative recovery, motion sickness, or gastrointestinal disorders.
Antiemetics work by targeting specific pathways in the body that trigger emesis. One common mechanism involves blocking dopamine receptors in the brain, as dopamine plays a significant role in triggering the vomiting reflex. This class of antiemetics is known as dopamine antagonists. Another mechanism involves inhibiting serotonin receptors, which are associated with nausea and vomiting. These agents, called serotonin antagonists, effectively reduce these symptoms.
In addition to dopamine and serotonin antagonists, other types of antiemetics include neurokinin-1 receptor antagonists, antihistamines, and anticholinergics. Each of these classes acts on different pathways in the body to provide relief from nausea and vomiting.
Pharmaceutical companies manufacture antiemetic APIs in accordance with strict quality control guidelines and regulations. These APIs serve as the active ingredients in various formulations, such as tablets, capsules, injections, or suppositories, designed to deliver the desired therapeutic effects.
Overall, antiemetic APIs form an essential category in the pharmaceutical industry, addressing the significant need for effective management of nausea and vomiting. Their development and availability greatly contribute to enhancing patient comfort and quality of life during various medical treatments and conditions.
Ondansetron manufacturers | traders | suppliers
We have 17 companies offering Ondansetron produced in 4 different countries.
Get in contact with the supplier of your choice:
- Gonane Pharma from India, product country of origin India
- Fuan Pharmaceutical (Group) Co., LTD. from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- SETV Global from India, product country of origin India
- Teva API from Israel, product country of origin Unknown
- Gedeon Richter from Hungary, product country of origin Unknown
- JPN Pharma from India, product country of origin India
- Lorem from Spain, product country of origin Spain
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
- Natco Pharma from India, product country of origin India
- Dr. Reddy's from India, product country of origin India
- Hikal from India, product country of origin India
- Ipca Labs. from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
- Cipla from India, product country of origin Unknown
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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