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Finerenone API Manufacturers & Suppliers

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API | Excipient name:

Finerenone 

Synonyms:

BAY 94-8862  

Cas Number:

1050477-31-0 

DrugBank number:

DB16165 

Unique Ingredient Identifier:

DE2O63YV8R

Finerenone is a type of Aldosterone antagonists

Aldosterone antagonists are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in the treatment of various medical conditions. These compounds act as competitive inhibitors of aldosterone, a hormone produced by the adrenal glands. By blocking the aldosterone receptors, these antagonists help regulate the body's electrolyte balance and fluid retention.

Aldosterone antagonists are primarily used in the management of cardiovascular diseases, such as heart failure and hypertension. These medications effectively reduce blood pressure by inhibiting aldosterone's action on the kidneys, leading to decreased sodium and water reabsorption and increased potassium excretion. This mechanism not only alleviates the strain on the heart but also prevents the expansion of blood volume, ultimately improving cardiac function.

Furthermore, aldosterone antagonists have demonstrated their effectiveness in treating other conditions, including primary aldosteronism, a disorder characterized by excessive aldosterone production. By blocking the aldosterone receptors, these drugs counteract the excessive hormonal effects and aid in normalizing blood pressure and electrolyte levels.

Spironolactone and eplerenone are two prominent examples of aldosterone antagonists widely used in clinical practice. These medications are available in various formulations, including oral tablets and suspensions, to cater to individual patient needs.

In conclusion, aldosterone antagonists are a vital subcategory of pharmaceutical APIs with significant therapeutic implications. Their ability to regulate aldosterone activity makes them valuable in managing cardiovascular disorders and conditions associated with abnormal aldosterone production. These medications provide a targeted approach to restore electrolyte balance, reduce fluid retention, and improve overall cardiovascular health.

Finerenone (Aldosterone antagonists), classified under Antihypertensive agents

Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.

• Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
• Sichuan Elixir Pharmaceutical Co., Ltd from China, product country of origin China
• Sinoway industrial Co.,Ltd from China, product country of origin China
• Apino Pharma Co., Ltd. from China, product country of origin China
• Dr. Reddy's from India, product country of origin India

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