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Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Looking for Guanfacine API 29110-47-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Guanfacine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Guanfacine
- Synonyms:
- Estulic , Guanfacina , Guanfacinum , Guanfacine Hydrochloride
- Cas Number:
- 29110-47-2
- DrugBank number:
- DB01018
- Unique Ingredient Identifier:
- 30OMY4G3MK
About Guanfacine
Want to know more about Guanfacine? Guanfacine, or BS 100-141, is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension10 but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Guanfacine is a type of Alpha-2 adrenergic agonist
Alpha-2 adrenergic agonists are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) commonly used in the field of medicine. These compounds specifically target and activate alpha-2 adrenergic receptors in the body, which are found primarily in the central nervous system.
Alpha-2 adrenergic agonists exhibit a wide range of pharmacological effects due to their interaction with these receptors. One of their main applications is in the management of hypertension (high blood pressure). By stimulating the alpha-2 adrenergic receptors in the brain, these agonists inhibit the release of norepinephrine, a neurotransmitter that constricts blood vessels. This action leads to vasodilation, resulting in a decrease in blood pressure.
Furthermore, alpha-2 adrenergic agonists are also utilized in ophthalmology to treat conditions such as glaucoma. By reducing the production of aqueous humor, the fluid responsible for intraocular pressure, these compounds help alleviate the symptoms of this eye disorder.
In addition to their cardiovascular and ophthalmological applications, alpha-2 adrenergic agonists have been investigated for their potential role in pain management, sedation, and even in the treatment of attention deficit hyperactivity disorder (ADHD). Research into these areas is ongoing, highlighting the versatility and potential of this API subcategory.
Overall, alpha-2 adrenergic agonists are valuable pharmaceutical compounds that play a crucial role in the treatment of hypertension, glaucoma, and other related disorders. Through their selective interaction with alpha-2 adrenergic receptors, these APIs offer a targeted approach to achieving desired therapeutic outcomes.
Guanfacine (Alpha-2 adrenergic agonist), classified under Antihypertensive agents
Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.
Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.
ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.
Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.
Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.
In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.
Guanfacine manufacturers | traders | suppliers
We have 5 companies offering Guanfacine produced in 3 different countries.
Get in contact with the supplier of your choice:
- Quimica Sintetica from Spain, product country of origin Unknown
- Torrent Pharma from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Procos from Italy, product country of origin Italy
- Medichem from Spain, product country of origin Unknown
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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