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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

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India

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Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Spain
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Germany

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Italy
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Located in:

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Looking for Candesartan API 139481-59-7?

Description:
Here you will find a list of producers, manufacturers and traders of Candesartan. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Candesartan 
Synonyms:
Blopress , Candesartan cilexetil  
Cas Number:
139481-59-7 
DrugBank number:
DB00796 
Unique Ingredient Identifier:
S8Q36MD2XX

About Candesartan

Do you want to know more about Candesartan cilexetil? You can find a small explanation about it here. Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II.

Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.

Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.

Candesartan is a type of Angiotensin Receptor Blockers


Angiotensin Receptor Blockers (ARBs) are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) commonly used in the treatment of hypertension and various cardiovascular conditions. ARBs work by selectively blocking the angiotensin II type 1 receptors, which are responsible for causing vasoconstriction and promoting the release of aldosterone, a hormone that regulates blood pressure and fluid balance.

These APIs are highly effective in reducing blood pressure by preventing angiotensin II from binding to its receptors, thereby dilating blood vessels and reducing peripheral resistance. By inhibiting the angiotensin II signaling pathway, ARBs help relax and widen the blood vessels, which subsequently lowers blood pressure.

Some commonly prescribed ARBs include losartan, valsartan, and candesartan. These drugs offer several advantages over other antihypertensive medications, such as a lower risk of side effects and better tolerability. ARBs are also considered beneficial for patients with certain comorbidities, including heart failure and diabetic nephropathy.

Pharmaceutical companies play a crucial role in the development and manufacturing of high-quality ARB APIs. Stringent quality control measures and adherence to regulatory guidelines ensure the safety, efficacy, and reliability of these APIs. Moreover, the market demand for ARBs is consistently growing, presenting a significant opportunity for pharmaceutical companies to cater to the increasing medical needs of patients suffering from hypertension and related cardiovascular conditions.

In conclusion, Angiotensin Receptor Blockers (ARBs) are a valuable subcategory of pharmaceutical APIs that effectively manage hypertension and cardiovascular diseases. With their ability to target the angiotensin II receptors, ARBs provide a reliable therapeutic option for patients and contribute to improving overall cardiovascular health.


Candesartan (Angiotensin Receptor Blockers), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Candesartan manufacturers | traders | suppliers

We have 33 companies offering Candesartan produced in 6 different countries.

Get in contact with the supplier of your choice:

  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Dr. Reddy's from India, product country of origin India
  • Zhejiang Kinglyuan from China, product country of origin China
  • Glochem from India, product country of origin India
  • Teva API from Israel, product country of origin Unknown
  • Quimica Sintetica from Spain, product country of origin Unknown
  • Unimark Remedies from India, product country of origin India
  • Zhejiang Tianyu from China, product country of origin China
  • Menovo from China, product country of origin China
  • Zhuhai Rundu from China, product country of origin China
  • Chromo Labs. from India, product country of origin India
  • KRKA from Slovenia, product country of origin Unknown
  • Hanmi Fine Chemical from South Korea, product country of origin South Korea
  • Kolon Life Science from South Korea, product country of origin South Korea
  • Sumitomo Chemical from Japan, product country of origin Japan
  • Flavine from Germany, product country of origin Unknown
  • Takeda Pharma from Japan, product country of origin Japan
  • Torrent Pharma from India, product country of origin India
  • Ouchi Shinko Chemical Industry from Japan, product country of origin Japan
  • Mahalaxmi Chemi Pharm from India, product country of origin India
  • Yungjin Pharmaceutical from South Korea, product country of origin South Korea
  • Lupin from India, product country of origin India
  • Dipharma Francis S.r.l. from Italy, product country of origin Italy
  • Aurobindo from India, product country of origin India
  • Mylan from India, product country of origin Unknown
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Lek Pharma from Slovenia, product country of origin Unknown
  • Jiangxi Synergy from China, product country of origin China
  • Hetero Labs from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Jubilant Generics from India, product country of origin Unknown
  • Procos from Italy, product country of origin Italy

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