Valsartan API manufacturers
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Distributor
Produced in:
Established in: 1993
MOQ: 15 kg
Employees: 700+

We can develop new APIs upon request

GMP, EMA/FDA, OSHAS cert. CDMO

12 local offices, strategically around the world
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Distributor

Supply to over 40 countries around the globe

Contract manufacturing (CRAMS) services

High quality product & superior client service
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Distributor
Produced in:

Established in: 1963
MOQ: -
Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe
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Producer
Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms
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Distributor
Produced in:
Established in: 1923
MOQ: 25 kg
Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation
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Produced in:

Established in: 1944
MOQ: -
Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers
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Produced in:
Established in: 1983
MOQ: -
Employees: 200+

Presence in more than 75 countries in the world

We delivery top quality APIs as per global standards

manufacture 45+ APIs including 10 essential drugs
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Looking for Valsartan 137862-53-4?
- Description:
- Here you will find a list of producers, manufacturers and traders of Valsartan. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Valsartan
- Synonyms:
- Diovan , Valsartan Process II
- Cas Number:
- 137862-53-4
- DrugBank number:
- DB00177
- Unique Ingredient Identifier:
- 80M03YXJ7I
About Valsartan
Want to know more about Valsartan? Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Valsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.
Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
Check who is selling Valsartan in the overview above.
Valsartan is a type of Angiotensin Receptor Blockers
Angiotensin Receptor Blockers (ARBs) are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) commonly used in the treatment of hypertension and various cardiovascular conditions. ARBs work by selectively blocking the angiotensin II type 1 receptors, which are responsible for causing vasoconstriction and promoting the release of aldosterone, a hormone that regulates blood pressure and fluid balance.
These APIs are highly effective in reducing blood pressure by preventing angiotensin II from binding to its receptors, thereby dilating blood vessels and reducing peripheral resistance. By inhibiting the angiotensin II signaling pathway, ARBs help relax and widen the blood vessels, which subsequently lowers blood pressure.
Some commonly prescribed ARBs include losartan, valsartan, and candesartan. These drugs offer several advantages over other antihypertensive medications, such as a lower risk of side effects and better tolerability. ARBs are also considered beneficial for patients with certain comorbidities, including heart failure and diabetic nephropathy.
Pharmaceutical companies play a crucial role in the development and manufacturing of high-quality ARB APIs. Stringent quality control measures and adherence to regulatory guidelines ensure the safety, efficacy, and reliability of these APIs. Moreover, the market demand for ARBs is consistently growing, presenting a significant opportunity for pharmaceutical companies to cater to the increasing medical needs of patients suffering from hypertension and related cardiovascular conditions.
In conclusion, Angiotensin Receptor Blockers (ARBs) are a valuable subcategory of pharmaceutical APIs that effectively manage hypertension and cardiovascular diseases. With their ability to target the angiotensin II receptors, ARBs provide a reliable therapeutic option for patients and contribute to improving overall cardiovascular health.
Valsartan (Angiotensin Receptor Blockers), classified under Antihypertensive agents
Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.
Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.
ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.
Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.
Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.
In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.
Valsartan manufacturers | traders | suppliers
We have 37 companies offering Valsartan from 7 different countries.
Get in contact with the supplier of your choice:
- SUANFARMA from Spain
- Hari Ganesh Pharma Private Limited from India
- TIEFENBACHER API + Ingredients from Germany
- Shandong Octagon Chemicals Limited from China
- Otto Brandes GmbH from Germany
- Cadila Healthcare from India
- Lupin from India
- Zhejiang Hisun Pharma from China
- Chromo Labs. from India
- Teva API from Israel
- Menovo from China
- Shin Poong Pharm from South Korea
- Sumitomo Chemical from Japan
- Harman Finochem from India
- Kolon Life Science from South Korea
- Cadila Pharma from India
- Zhuhai Rundu from China
- Laurus Labs from India
- Kyowa Pharma Chem. from Japan
- KRKA from Slovenia
- Zhejiang Changming from China
- Zhejiang Tianyu from China
- Signa from Mexico
- Shaoxing Hantai Pharma from China
- Divis Labs. from India
- Alembic Pharma from India
- MSN Life Sciences from India
- Teva Pharma ind. from Israel
- Granules India from India
- Daewoong Bio from South Korea
- Jubilant Generics from India
- Hetero Labs from India
- Ipca Labs. from India
- Aurobindo from India
- Mylan from India
- Dr. Reddy's from India
- Sun Pharma from India
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