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Heparinate (Heparin sodium) API Manufacturers & Suppliers

Looking for Heparin sodium API 9005-49-6?

Description:

Here you will find a list of producers, manufacturers and distributors of Heparin sodium. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Heparin sodium 

Synonyms:

Calciparine , Eparina , Hep-lock , Heparinate , Heparinic acid , Liquaemin , Panheprin , Unfractionated heparin , Heparinum , Heparin sodium For parenteral preparations , Heparin , Heparinum natricum  

Cas Number:

9005-49-6 

DrugBank number:

DB01109 

Unique Ingredient Identifier:

4QW4AN84NQ

Heparin sodium is a type of Anticoagulant proteins

Anticoagulant proteins are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in preventing the formation of blood clots. These proteins are naturally occurring substances that interfere with the clotting cascade, a complex series of reactions that lead to blood coagulation.

One of the well-known anticoagulant proteins is hirudin, derived from leeches. Hirudin acts by inhibiting thrombin, a key enzyme involved in blood clot formation. Another notable anticoagulant protein is antithrombin III, which blocks several clotting factors, including thrombin and factors IXa, Xa, XIa, and XIIa. These proteins are widely used in the pharmaceutical industry to develop medications for conditions such as deep vein thrombosis, pulmonary embolism, and stroke prevention.

The production of anticoagulant proteins involves advanced biotechnological processes. Recombinant DNA technology and genetic engineering techniques are employed to produce these proteins in large quantities. The proteins are expressed in host organisms such as bacteria, yeast, or mammalian cells, and then purified through various chromatographic and filtration steps to obtain a highly pure and active form.

The development of anticoagulant proteins has significantly improved the treatment and management of thrombotic disorders. These APIs have proven to be effective in preventing clot formation, reducing the risk of life-threatening complications. However, it is crucial to administer anticoagulant proteins under medical supervision due to their potential side effects and the need for precise dosing.

In conclusion, anticoagulant proteins are a vital subcategory of pharmaceutical APIs that act by inhibiting key components of the clotting cascade. Their production involves advanced biotechnological processes, and they have greatly enhanced the management of thrombotic disorders. Proper medical guidance is essential for their safe and effective use.

Heparin sodium (Anticoagulant proteins), classified under Anticoagulants

Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.

• Chr. Olesen Group from Denmark, product country of origin Italy
• Sinoway industrial Co.,Ltd from China, product country of origin China
• Suanfarma from Spain, product country of origin European Union
• Apino Pharma Co., Ltd. from China, product country of origin China
• Nanjing Hanxin Pharmaceutical Technology Co.,Ltd. from China, product country of origin China
• AXXO GmbH from Germany, product country of origin World
• Duchefa Farma B.V. from Netherlands, product country of origin Italy
• Biofer from Italy, product country of origin Italy
• Opocrin S-C Plant from Italy, product country of origin Italy
• Shenzhen Hepalink from China, product country of origin China
• Scientific Protein Labs. from United States, product country of origin United States
• Lab. Derivati Organici from Italy, product country of origin Italy
• Sandoz from Austria, product country of origin Unknown
• Hubei Enoray  from China, product country of origin China
• API Corp. from Japan, product country of origin Japan
• Qingdao Jiulong from China, product country of origin China
• Yino Pharma from China, product country of origin China
• Nanjing King-Friend BC from China, product country of origin China
• Dongying Tiandong Pharmaceutical Co Ltd from China, product country of origin China
• Shandong Chen Zhong from China, product country of origin China
• Leo Pharma from Denmark, product country of origin Denmark
• Yantai Dongcheng Bio. from China, product country of origin China
• Shaoxing Hantai Pharma from China, product country of origin China
• Sanofi from France, product country of origin Unknown

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