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Heparinate (Heparin sodium) API Manufacturers
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Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
Passed ISO9001:2015 and SGS audit
Provide one-stop CDMO service from R&D to production
Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Distributor
Produced in:
Established in: 1885
MOQ: -
Employees: 150
Trusted for 140 years
Global distribution business with API manufacturing facilities
European company with presence in 3 continents
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Distributor
Produced in:
Established in: 1993
MOQ: 15 kg
Employees: 700+
We can develop new APIs upon request
GMP, EMA/FDA, OSHAS cert. CDMO
12 local offices, strategically around the world
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Produced in:
Established in: 2017
MOQ: -
Employees: 200+
Manufacturing facility approved by FDA and GMP certified
Obtained CNAS laboratory accreditation certificate
Subsidiary of the US listed group Amphastar Pharmaceuticals
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Produced in:
Established in: 2019
MOQ: 1 kg
Employees: 10+
Focused on pharmaceutical industry
Reasonable price for the customers
Full service from R&D stage to commercial stage
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Distributor
Produced in:
Established in: 1968
MOQ: 125 mu
Employees: 50+
Warehouse stock of nearly all APIs
GMP, GDP and ISO certified
Customisable (small-sized) packages
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Looking for Heparin sodium API 9005-49-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Heparin sodium. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Heparin sodium
- Synonyms:
- Calciparine , Eparina , Hep-lock , Heparinate , Heparinic acid , Liquaemin , Panheprin , Unfractionated heparin , Heparinum , Heparin sodium For parenteral preparations , Heparin , Heparinum natricum
- Cas Number:
- 9005-49-6
- DrugBank number:
- DB01109
- Unique Ingredient Identifier:
- 4QW4AN84NQ
About Heparin sodium
Here is a short description about Heparin. Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.
UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about kDa whereas it is 15 kDa for UH;UH requires continuous infusions;activated partial prothrombin time (aPTT) monitoring is required when using UH;and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Heparin sodium is a type of Anticoagulant proteins
Anticoagulant proteins are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in preventing the formation of blood clots. These proteins are naturally occurring substances that interfere with the clotting cascade, a complex series of reactions that lead to blood coagulation.
One of the well-known anticoagulant proteins is hirudin, derived from leeches. Hirudin acts by inhibiting thrombin, a key enzyme involved in blood clot formation. Another notable anticoagulant protein is antithrombin III, which blocks several clotting factors, including thrombin and factors IXa, Xa, XIa, and XIIa. These proteins are widely used in the pharmaceutical industry to develop medications for conditions such as deep vein thrombosis, pulmonary embolism, and stroke prevention.
The production of anticoagulant proteins involves advanced biotechnological processes. Recombinant DNA technology and genetic engineering techniques are employed to produce these proteins in large quantities. The proteins are expressed in host organisms such as bacteria, yeast, or mammalian cells, and then purified through various chromatographic and filtration steps to obtain a highly pure and active form.
The development of anticoagulant proteins has significantly improved the treatment and management of thrombotic disorders. These APIs have proven to be effective in preventing clot formation, reducing the risk of life-threatening complications. However, it is crucial to administer anticoagulant proteins under medical supervision due to their potential side effects and the need for precise dosing.
In conclusion, anticoagulant proteins are a vital subcategory of pharmaceutical APIs that act by inhibiting key components of the clotting cascade. Their production involves advanced biotechnological processes, and they have greatly enhanced the management of thrombotic disorders. Proper medical guidance is essential for their safe and effective use.
Heparin sodium (Anticoagulant proteins), classified under Anticoagulants
Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.
There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.
Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.
While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.
In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.
Heparin sodium manufacturers | traders | suppliers
We have 23 companies offering Heparin sodium produced in 7 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Chr. Olesen Group from Denmark, product country of origin Italy
- Suanfarma from Spain, product country of origin European Union
- Nanjing Hanxin Pharmaceutical Technology Co.,Ltd. from China, product country of origin China
- Apino Pharma Co., Ltd. from China, product country of origin China
- Duchefa Farma B.V. from Netherlands, product country of origin Italy
- Lab. Derivati Organici from Italy, product country of origin Italy
- Hubei Enoray from China, product country of origin China
- Sandoz from Austria, product country of origin Unknown
- Scientific Protein Labs. from United States, product country of origin United States
- Shenzhen Hepalink from China, product country of origin China
- Shandong Chen Zhong from China, product country of origin China
- Nanjing King-Friend BC from China, product country of origin China
- Dongying Tiandong Pharmaceutical Co Ltd from China, product country of origin China
- Yino Pharma from China, product country of origin China
- Qingdao Jiulong from China, product country of origin China
- API Corp. from Japan, product country of origin Japan
- Opocrin S-C Plant from Italy, product country of origin Italy
- Biofer from Italy, product country of origin Italy
- Leo Pharma from Denmark, product country of origin Denmark
- Sanofi from France, product country of origin Unknown
- Shaoxing Hantai Pharma from China, product country of origin China
- Yantai Dongcheng Bio. from China, product country of origin China
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