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Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
|---|---|---|---|---|---|---|---|---|
| 20-Oct-2023 | (Hidden) | 
Switzerland
| MERCK PERU... | 
Peru
| DOLASETRON... | 0.31 | $ @36$-7! | Check all data |
| 30-Jun-2022 | (Hidden) | 
India
| CAMBREX PH... | 
United States
| Dolasetron... | 1.96 | $ @36$-7! | |
| 01-Jun-2022 | (Hidden) |
India
| CAMBREX PH... |
United States
| Dolasetron... | 3 | $ @36$-7! |
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Looking for Dolasetron API 115956-12-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Dolasetron. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Dolasetron
- Synonyms:
- Dolasetron , Dolasetron , Dolasetronum
- Cas Number:
- 115956-12-2
- DrugBank number:
- DB00757
- Unique Ingredient Identifier:
- 82WI2L7Q6E
About Dolasetron
What makes Dolasetron unique? Dolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.
You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.
Dolasetron is a type of Antiemetics
Antiemetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate and prevent nausea and vomiting, also known as emesis. They play a vital role in managing these distressing symptoms, which can be caused by various factors such as chemotherapy, postoperative recovery, motion sickness, or gastrointestinal disorders.
Antiemetics work by targeting specific pathways in the body that trigger emesis. One common mechanism involves blocking dopamine receptors in the brain, as dopamine plays a significant role in triggering the vomiting reflex. This class of antiemetics is known as dopamine antagonists. Another mechanism involves inhibiting serotonin receptors, which are associated with nausea and vomiting. These agents, called serotonin antagonists, effectively reduce these symptoms.
In addition to dopamine and serotonin antagonists, other types of antiemetics include neurokinin-1 receptor antagonists, antihistamines, and anticholinergics. Each of these classes acts on different pathways in the body to provide relief from nausea and vomiting.
Pharmaceutical companies manufacture antiemetic APIs in accordance with strict quality control guidelines and regulations. These APIs serve as the active ingredients in various formulations, such as tablets, capsules, injections, or suppositories, designed to deliver the desired therapeutic effects.
Overall, antiemetic APIs form an essential category in the pharmaceutical industry, addressing the significant need for effective management of nausea and vomiting. Their development and availability greatly contribute to enhancing patient comfort and quality of life during various medical treatments and conditions.
Dolasetron manufacturers | traders | suppliers
We have 5 companies offering Dolasetron produced in 3 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China, product country of origin China
- USV from India, product country of origin India
- Rolabo Outsourcing from Spain, product country of origin Spain
- Jiwan Pharmaceutical Technology Co.,Ltd from China, product country of origin China
- Emcure Pharma from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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