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Diphenhydraminum (Diphenhydramine) API Manufacturers
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Distributor
Produced in:
Established in: 1885
MOQ: -
Employees: 150
Trusted for 140 years
Global distribution business with API manufacturing facilities
European company with presence in 3 continents
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Distributor
Produced in:
Established in: 1991
MOQ: -
Employees: 50+
High quality APIs with competitive pricing
Worldwide network of GMP manufacturers
DMF support worldwide with unparalleled customer service
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Producer
Produced in:
Established in: 2005
MOQ: 1 kg
Employees: 85
Strict quality control
15 years of experience in API production
Provide OEM & ODM service
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Distributor
Produced in:
Established in: 1994
MOQ: -
Employees: 50+
26+ years of distribution expertise with regulatory excellence
16 worldwide locations supplying high quality ingredients
All our manufacturer partners are cGMP complaint
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Distributor
Produced in:
Established in: 1997
MOQ: -
Employees: 50
GMP and GDP certified
Biotechnological research leadership and manufacturer
Extensive distribution network for product global accessibility
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Distributor
Produced in:
Established in: 2005
MOQ: -
Employees: 200+
Portfolio of over 2,000 APIs
Precise quality control
End-to-end global regulatory support
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Distributor
Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
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Producer
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Producer
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Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Producer
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Producer
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Producer
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Producer
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Looking for Diphenhydramine API 58-73-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Diphenhydramine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Diphenhydramine
- Synonyms:
- Difenhidramina , Diphenhydraminum , Diphenhydramine hydrochloride , Diphenhydramine HCl
- Cas Number:
- 58-73-1
- DrugBank number:
- DB01075
- Unique Ingredient Identifier:
- 8GTS82S83M
About Diphenhydramine
Here is a short description about Diphenhydramine. Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties 16. As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the central nervous system While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold medications that have been marketed for night time use.
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Diphenhydramine is a type of Antihistamines
Antihistamines are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of allergies and allergic reactions. These compounds work by blocking the action of histamines, which are responsible for triggering allergic symptoms such as itching, sneezing, runny nose, and watery eyes.
Antihistamines can be classified into two main categories: first-generation and second-generation antihistamines. First-generation antihistamines, such as diphenhydramine and chlorpheniramine, have been in use for several decades. They are effective in relieving allergy symptoms but are associated with drowsiness and other side effects due to their ability to cross the blood-brain barrier.
On the other hand, second-generation antihistamines, including cetirizine, loratadine, and fexofenadine, offer similar allergy relief with fewer sedative effects. These newer antihistamines are preferred for their improved safety profiles, making them suitable for use during the day without causing significant drowsiness.
Antihistamines are available in various forms, including tablets, capsules, syrups, and topical creams. They are extensively used to manage conditions such as hay fever, hives, allergic rhinitis, and insect bites. Moreover, antihistamines may also be combined with decongestants or other medications to provide relief from nasal congestion and sinus symptoms.
As pharmaceutical APIs, antihistamines are produced through meticulous synthesis and manufacturing processes, adhering to strict quality standards. These APIs serve as the active components in various branded and generic pharmaceutical formulations, making them crucial in the pharmaceutical industry's production of allergy medications.
In conclusion, antihistamines are a significant subcategory of pharmaceutical APIs widely used for alleviating allergy symptoms. Their classification into first- and second-generation antihistamines offers options based on efficacy and sedative effects. By blocking histamines, antihistamines provide relief from common allergic reactions, making them essential in the development of effective allergy medications.
Diphenhydramine (Antihistamines), classified under Central Nervous System Agents
Central Nervous System (CNS) Agents are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that specifically target the central nervous system. The CNS encompasses the brain and spinal cord, playing a vital role in regulating and controlling various bodily functions, including cognition, movement, emotions, and sensory perception. These agents are designed to interact with specific receptors, enzymes, or ion channels within the CNS to modulate neural activity and restore normal functioning.
CNS agents comprise a diverse range of pharmaceutical APIs, including analgesics, anesthetics, antipsychotics, sedatives, hypnotics, anti-epileptics, and antidepressants. Each subcategory addresses distinct neurological disorders and conditions. For instance, analgesics alleviate pain by targeting receptors in the brain and spinal cord, while antipsychotics are employed to manage psychosis symptoms in mental illnesses such as schizophrenia.
The development of CNS agents involves rigorous research, molecular modeling, and extensive clinical trials to ensure safety, efficacy, and specific target engagement. Pharmaceutical companies invest significant resources in identifying novel drug targets, synthesizing new compounds, and optimizing their pharmacological properties. These agents undergo rigorous regulatory evaluations and must adhere to stringent quality standards and guidelines.
Given the prevalence of CNS disorders globally, the market demand for effective CNS agents is substantial. The development of innovative CNS APIs not only improves patient outcomes but also provides valuable commercial opportunities for pharmaceutical companies. Continued advancements in CNS agent research and development hold the promise of groundbreaking therapies that can improve the quality of life for individuals affected by neurological conditions.
Diphenhydramine manufacturers | traders | suppliers
We have 15 companies offering Diphenhydramine produced in 8 different countries.
Get in contact with the supplier of your choice:
- Chr. Olesen Group from Denmark, product country of origin India
- Pharm Rx Chemical Corp from United States, product country of origin China
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
- Rochem International, Inc. from United States, product country of origin United States
- AXXO GmbH from Germany, product country of origin World
- LGM Pharma from United States, product country of origin World
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Kongo Chemical from Japan, product country of origin Japan
- Albemarle from United States, product country of origin United States
- Medinex Labs. from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Shanghai Wonder Pharma from China, product country of origin China
- Wanbury from India, product country of origin India
- M2i Life from France, product country of origin France
- Recordati S.p.A. from Italy, product country of origin Italy
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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