Ketoconazole API Manufacturers

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Located in:

China

Produced in:

China

Established in: 2005

MOQ: 1 kg

Employees: 85

Strict quality control

15 years of experience in API production

Provide OEM & ODM service

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • MSDS

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Replies quickly

Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CEP

  • GMP

  • CoA

  • MSDS

  • BSE/TSE

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Produced in:

Unknown

Established in: 1886

MOQ: -

Employees: 275+

Raw materials, CMO and OTC products

Two GMP certified locations

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • MSDS

  • GMP

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Produced in:

India

Established in: 2018

MOQ: -

Employees: 200+

WHO GMP Approved sites for production

25+ years experience in manufacturing APIs for regulated markets

High quality product & superior client service

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • MSDS

  • BSE/TSE

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Produced in:

Mexico

Established in: 1968

MOQ: 100 g

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • ISO9001

  • MSDS

  • CoA

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Located in:

China

Produced in:

China

Established in: 1987

MOQ: -

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • MSDS

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Replies quickly

Located in:

Spain

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • DMF

  • CoA

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Replies slower than most

Located in:

Spain

Produced in:

Spain

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

  • GMP

Contact supplier

Replies slower than most

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • WC

  • CoA

Contact supplier

Replies slower than most

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • WC

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • FDA

  • GMP

  • ISO 9001

  • WHO-GMP

  • DMF

Contact supplier

Replies slower than most

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

Contact supplier

Replies slower than most

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • WC

  • CoA

  • DMF

Contact supplier

Replies slower than most

Located in:

Belgium

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • CEP

  • GMP

  • KDMF

  • DMF

Located in:

India

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • KDMF

  • GMP

  • coa

  • FDA

  • DMF

  • CEP

  • WC

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

Located in:

United Kingdom

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • WC

  • CoA

  • GMP

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Looking for Ketoconazole API 65277-42-1?

Description:
Here you will find a list of producers, manufacturers and distributors of Ketoconazole. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Ketoconazole 
Synonyms:
Extina , Ketoconazol , Ketoconazole , Ketoconazolum , Ketozole , Nizoral , Nizoral a-D , Xolegel  
Cas Number:
65277-42-1 
DrugBank number:
DB01026 
Unique Ingredient Identifier:
R9400W927I

About Ketoconazole

Why are people looking for Ketoconazole? Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus1 Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. At this time it was considered a significant improvement over previous antifungals, miconazole and clotrimazole, due to its broad spectrum and good absorption. However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis These effects combined with waning efficacy led to its eventual replacement by triazole agents, fluconazole, itraconazole, voriconazole, and posaconazole.

Ketoconazole and its predecessor clotrimazole continue to be used in topical formulations.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Ketoconazole is a type of Antimycotics


Antimycotics, a subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs), are essential in the treatment of various fungal infections. These powerful medications target and eliminate harmful fungi that can cause infections in humans.

Antimycotics are classified into two main types: systemic and topical. Systemic antimycotics are administered orally or intravenously and work by circulating throughout the body, treating systemic fungal infections that affect internal organs or spread throughout the bloodstream. On the other hand, topical antimycotics are applied externally to treat localized fungal infections such as athlete's foot or yeast infections.

The efficacy of antimycotics lies in their ability to disrupt fungal cell membranes, inhibit the synthesis of fungal DNA or proteins, or interfere with essential metabolic processes specific to fungi. This targeted action minimizes damage to human cells, making these medications relatively safe for patients.

Commonly prescribed antimycotics include azoles, polyenes, allylamines, and echinocandins. Azoles inhibit the synthesis of ergosterol, a vital component of fungal cell membranes, while polyenes bind to ergosterol, resulting in the formation of pores that lead to cell death. Allylamines disrupt the synthesis of ergosterol and inhibit the activity of squalene epoxidase, an enzyme involved in ergosterol production. Echinocandins target the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall.

Antimycotics play a crucial role in the management of fungal infections, offering relief to patients and aiding in their recovery. As with any medication, it is important to follow healthcare professionals' guidance regarding dosage, duration of treatment, and potential side effects to ensure optimal therapeutic outcomes.


Ketoconazole (Antimycotics), classified under Antifungals


Antifungals are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) designed to combat fungal infections. These medications are developed to target and eliminate fungi, including yeasts and molds, which can cause a range of diseases in humans and animals.

Antifungals work by interfering with specific components or processes essential for fungal growth and reproduction. They may inhibit the synthesis of fungal cell walls or disrupt the production of ergosterol, a crucial component of fungal cell membranes. By targeting these key mechanisms, antifungal APIs effectively hinder the growth and spread of fungal infections.

The diversity within the antifungal category is reflected in the various classes of antifungal APIs available. Azoles, polyenes, echinocandins, and allylamines are common classes of antifungals. Each class exhibits unique mechanisms of action and targets specific types of fungi. This diversity enables healthcare professionals to tailor treatment plans to the specific fungal infection, optimizing therapeutic outcomes.

Antifungal APIs find application in various pharmaceutical formulations, including oral medications, topical creams, ointments, and intravenous solutions. They are crucial for the treatment of common fungal infections like athlete's foot, ringworm, vaginal yeast infections, and oral thrush. Additionally, antifungals play a crucial role in managing serious systemic fungal infections that can pose significant health risks, especially in immunocompromised individuals.

Overall, antifungal APIs are indispensable tools in the fight against fungal infections, offering effective treatment options and improving the quality of life for patients suffering from these conditions. With ongoing research and development, the antifungal category continues to evolve, providing innovative solutions to combat the ever-changing landscape of fungal pathogens.



Ketoconazole manufacturers | traders | suppliers

We have 18 companies offering Ketoconazole produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Gonane Pharma from India, product country of origin India
  • Duchefa Farma B.V. from Netherlands, product country of origin Mexico
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Quimica Sintetica from Spain, product country of origin Unknown
  • Derivados Quimicos from Spain, product country of origin Spain
  • Gufic Biosciences from India, product country of origin India
  • Nanjing Baijingyu from China, product country of origin China
  • Prachi Pharmaceuticals from India, product country of origin India
  • Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
  • Sharon Bio-Medicine from India, product country of origin India
  • Janssen Pharma from Belgium, product country of origin Unknown
  • Piramal Pharma Solutions from India, product country of origin Unknown
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Piramal Healthcare from United Kingdom, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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