Antifungals


Antifungals are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) designed to combat fungal infections. These medications are developed to target and eliminate fungi, including yeasts and molds, which can cause a range of diseases in humans and animals.

Antifungals work by interfering with specific components or processes essential for fungal growth and reproduction. They may inhibit the synthesis of fungal cell walls or disrupt the production of ergosterol, a crucial component of fungal cell membranes. By targeting these key mechanisms, antifungal APIs effectively hinder the growth and spread of fungal infections.

The diversity within the antifungal category is reflected in the various classes of antifungal APIs available. Azoles, polyenes, echinocandins, and allylamines are common classes of antifungals. Each class exhibits unique mechanisms of action and targets specific types of fungi. This diversity enables healthcare professionals to tailor treatment plans to the specific fungal infection, optimizing therapeutic outcomes.

Antifungal APIs find application in various pharmaceutical formulations, including oral medications, topical creams, ointments, and intravenous solutions. They are crucial for the treatment of common fungal infections like athlete's foot, ringworm, vaginal yeast infections, and oral thrush. Additionally, antifungals play a crucial role in managing serious systemic fungal infections that can pose significant health risks, especially in immunocompromised individuals.

Overall, antifungal APIs are indispensable tools in the fight against fungal infections, offering effective treatment options and improving the quality of life for patients suffering from these conditions. With ongoing research and development, the antifungal category continues to evolve, providing innovative solutions to combat the ever-changing landscape of fungal pathogens.

NameCAS number
Aciclovir59277-89-3
Amorolfine
Amphotericin B1397-89-3
Anidulafungin166663-25-8
Bifonazole60628-96-8
Butenafine101828-21-1
Butoconazole64872-76-0
Caspofungin162808-62-0
Chloroxine773-76-2
Ciclopirox29342-05-0
Clioquinol130-26-7
Clotrimazole23593-75-1
Econazole27220-47-9
Efinaconazole164650-44-6
Ergosterol57-87-4
Fenticonazole72479-26-6
Fluconazole86386-73-4
Flucytosine2022-85-7
Flutrimazole
Fosravuconazole L-lysine ethanolate182760-06-1
Griseofulvin126-07-8
Isavuconazole241479-67-4
Isavuconazonium742049-41-8
Isavuconazonium sulfate960404-48-2
Isoconazole27523-40-6
Isoconazole nitrate
Itraconazole84625-61-6
Ketoconazole65277-42-1
Luliconazole187164-19-8
Micafungin235114-32-6
Miconazole22916-47-8
Naftifine65472-88-0
Natamycin7681-93-8
Neticonazole130726-68-0
Nystatin1400-61-9
Oteseconazole1340593-59-0
Oxiconazole64211-45-6
Piroctone olamine68890-66-4
Posaconazole171228-49-2
Ravuconazole182760-06-1
Rezafungin179324-69-7
Selenium Sulfide7488-56-4
Sertaconazole99592-32-2
Sulconazole61318-90-9
Tavaborole174671-46-6
Terbinafine91161-71-6
Terconazole67915-31-5
Tioconazole65899-73-2
Tolnaftate2398-96-1
Undecylenic acid
Voriconazole137234-62-9