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Dactinomycin
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Looking for Dactinomycin API 50-76-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Dactinomycin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Dactinomycin
- Synonyms:
- ActD , Actinomycin C1 , Actinomycin D , Actinomycin iv , Dactinomicina , Dactinomycin , Dactinomycine , Dactinomycinum , Meractinomycin
- Cas Number:
- 50-76-0
- DrugBank number:
- DB00970
- Unique Ingredient Identifier:
- 1CC1JFE158
About Dactinomycin
Here is a short description about Dactinomycin. A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Dactinomycin is a type of Antineoplastics
Antineoplastics are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) primarily used in the treatment of cancer. These powerful substances inhibit or destroy the growth of cancer cells, thus impeding the progression of malignancies.
Antineoplastics exert their therapeutic effects through various mechanisms. Some APIs interfere with DNA replication, inhibiting the division and proliferation of cancer cells. Others target specific proteins or enzymes involved in tumor growth, effectively blocking their function. Additionally, certain antineoplastic agents induce programmed cell death, known as apoptosis, in cancer cells.
These APIs find application in a wide range of cancer treatments, including chemotherapy, targeted therapy, immunotherapy, and hormone therapy. They are often administered in combination with other drugs to optimize therapeutic outcomes and minimize drug resistance.
Antineoplastics are typically synthesized through complex chemical processes, ensuring high purity and potency. Stringent quality control measures are implemented throughout manufacturing to meet regulatory standards and ensure patient safety.
Although antineoplastics offer significant benefits in treating cancer, they can also cause adverse effects due to their cytotoxic nature. Common side effects include bone marrow suppression, gastrointestinal disturbances, hair loss, and immune system suppression. Close monitoring and supportive care are essential to manage these side effects effectively.
In conclusion, antineoplastics are a vital category of pharmaceutical APIs used in the treatment of cancer. Through their diverse mechanisms of action, these compounds play a critical role in combating malignancies and improving patient outcomes.
Dactinomycin manufacturers | traders | suppliers
We have 2 companies offering Dactinomycin produced in 2 different countries.
Get in contact with the supplier of your choice:
- Zhejiang Hisun Pharma from China, product country of origin China
- Sigma-Aldrich from United States, product country of origin Unknown
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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