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Edoxaban API Manufacturers
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Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
---|---|---|---|---|---|---|---|---|
27-Sep-2024 | (Hidden) | India | SHIGEMATSU... | Japan | EDOXABAN-D... | No data available | $ @36$-7! | Check all data |
26-Sep-2024 | (Hidden) | India | AIRPHARM S... | Spain | ACTIVE PHA... | 1 | $ @36$-7! | |
25-Sep-2024 | (Hidden) | India | BORYUNG CO... | Korea | ACTIVE PHA... | 1 | $ @36$-7! |
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Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
ISO 9001:2015 & SGS audited supplier
One-stop CDMO Solutions for APl and Key intermediates
Specialized in APIs & Pharmaceutical Intermediates for 37 years
+ 0
All certificates
Producer
Produced in:
Established in: 1984
MOQ: -
Employees: 2000+
Vertically integrated company
Largest producer of Montelukast in the world
USFDA & WHO GMP approved API plants
+ 0
All certificates
Distributor
Produced in:
Established in: 1994
MOQ: -
Employees: 50+
26+ years of distribution expertise with regulatory excellence
16 worldwide locations supplying high quality ingredients
All our manufacturer partners are cGMP complaint
+ 0
All certificates
Distributor
Produced in:
Established in: 2011
MOQ: 10 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
+ 0
All certificates
Distributor
Produced in:
Established in: 1997
MOQ: -
Employees: 50
GMP and GDP certified
Biotechnological research leadership and manufacturer
Extensive distribution network for product global accessibility
+ 0
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Producer
Produced in:
Established in: 2019
MOQ: 1 kg
Employees: 10+
Focused on pharmaceutical industry
Reasonable price for the customers
Full service from R&D stage to commercial stage
+ 0
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Producer
+ 0
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Producer
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Producer
Produced in:
Established in: 1984
MOQ: -
Employees: 21,650
Diverse portfolio of 180+APIs
1754+ DMF across global markets
1100+ patents filed, and more than 70 own patents granted
+ 0
All certificates
Producer
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Looking for Edoxaban API 480449-70-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Edoxaban. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Edoxaban
- Synonyms:
- Edoxaban Tosylate
- Cas Number:
- 480449-70-5
- DrugBank number:
- DB09075
- Unique Ingredient Identifier:
- NDU3J18APO
About Edoxaban
So, what does it do? Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) following 5-10 days of initial therapy with a parenteral anticoagulant. Traditionally, warfarin, a vitamin K antagonist, was used for stroke prevention in these individuals but effective use of this drug is limited by it's delayed onset, narrow therapeutic window, need for regular monitoring and INR testing, and numerous drug-drug and drug-food interactions.
This has prompted enthusiasm for newer agents such as dabigatran, apixaban, and rivaroxaban for effective clot prevention. In addition to once daily dosing, the benefits over warfarin also include significant reductions in hemorrhagic stroke and GI bleeding, and improved compliance, which is beneficial as many patients will be on lifelong therapy.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Edoxaban is a type of Antithrombotics
Antithrombotics, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in preventing and treating thrombotic disorders, which are characterized by the formation of blood clots within blood vessels. These medications are essential in reducing the risk of thrombosis, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke, which can lead to severe health complications.
Antithrombotics exert their therapeutic effects through various mechanisms. One commonly used class of antithrombotics is anticoagulants, which inhibit the clotting process by interfering with the formation of blood clots. These drugs include heparin, warfarin, and direct oral anticoagulants (DOACs). They are administered to patients with conditions like atrial fibrillation, venous thromboembolism, or mechanical heart valves to prevent clot formation.
Another class of antithrombotics is antiplatelet agents, which prevent platelet aggregation, an essential step in blood clot formation. Aspirin, clopidogrel, and ticagrelor are well-known antiplatelet drugs used to prevent thrombosis in patients with coronary artery disease, ischemic stroke, or peripheral artery disease.
Antithrombotics are typically prescribed based on the individual patient's risk factors, medical history, and the specific thrombotic condition being treated. Dosage and administration instructions may vary depending on the drug's pharmacokinetic profile and desired therapeutic outcomes.
As with any medication, antithrombotics may have potential side effects, such as increased bleeding risk. Therefore, healthcare professionals carefully assess the patient's overall health status, including any underlying conditions, before prescribing these medications.
In conclusion, antithrombotics are a crucial subcategory of pharmaceutical APIs that play a vital role in preventing and treating thrombotic disorders. By inhibiting clot formation through various mechanisms, these medications significantly contribute to reducing the risk of serious complications associated with blood clots.
Edoxaban (Antithrombotics), classified under Anticoagulants
Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.
There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.
Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.
While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.
In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.
Edoxaban manufacturers | traders | suppliers
We have 10 companies offering Edoxaban produced in 4 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Morepen Laboratories Ltd. from India, product country of origin India
- Rochem International, Inc. from United States, product country of origin United States
- Shandong Octagon Chemicals Limited from China, product country of origin China
- AXXO GmbH from Germany, product country of origin World
- Apino Pharma Co., Ltd. from China, product country of origin China
- Honour Lab from India, product country of origin India
- Zhejiang Supor from China, product country of origin China
- Dr. Reddy's from India, product country of origin India
- MSN Life Sciences from India, product country of origin India
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