Fondaparinux sodium API Manufacturers

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TOP RANKING

Located in:

China

Produced in:

China

Established in: 1987

MOQ: 100 g

Employees: 50+

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Specialized in APIs & Pharmaceutical Intermediates for 37 years

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TOP RANKING

Located in:

India

Producer

Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

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Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

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Produced in:

China

Established in: 2011

MOQ: 10 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Located in:

China

Producer

Produced in:

China

MOQ: -

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Replies slower than most

Located in:

Taiwan

Produced in:

Taiwan

MOQ: -

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Replies slower than most

Located in:

United States

Produced in:

United States

MOQ: -

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Looking for Fondaparinux sodium API 114870-03-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Fondaparinux sodium. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Fondaparinux sodium 
Synonyms:
Arixtra  
Cas Number:
114870-03-0 
DrugBank number:
DB00569 
Unique Ingredient Identifier:
X0Q6N9USOZ

About Fondaparinux sodium

Want to know what Fondaparinux is used for? Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII). Once bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold.

Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. Fondaparinux may be used: to prevent venous thromboembolism in patients who have undergone orthopedic surgery of the lower limbs (e.g.). hip fracture, hip replacement and knee surgery);to prevent VTE in patients undergoing abdominal surgery who are are at high risk of thromboembolic complications;in the treatment of deep vein thrombosis (DVT) and pumonary embolism (PE);in the management of unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI);and in the management of ST segment elevation myocardial infarction (STEMI).

Ask the supplier for a certificate of analysis to find out more about the quality of Fondaparinux.

Fondaparinux sodium is a type of Antithrombotics


Antithrombotics, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in preventing and treating thrombotic disorders, which are characterized by the formation of blood clots within blood vessels. These medications are essential in reducing the risk of thrombosis, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke, which can lead to severe health complications.

Antithrombotics exert their therapeutic effects through various mechanisms. One commonly used class of antithrombotics is anticoagulants, which inhibit the clotting process by interfering with the formation of blood clots. These drugs include heparin, warfarin, and direct oral anticoagulants (DOACs). They are administered to patients with conditions like atrial fibrillation, venous thromboembolism, or mechanical heart valves to prevent clot formation.

Another class of antithrombotics is antiplatelet agents, which prevent platelet aggregation, an essential step in blood clot formation. Aspirin, clopidogrel, and ticagrelor are well-known antiplatelet drugs used to prevent thrombosis in patients with coronary artery disease, ischemic stroke, or peripheral artery disease.

Antithrombotics are typically prescribed based on the individual patient's risk factors, medical history, and the specific thrombotic condition being treated. Dosage and administration instructions may vary depending on the drug's pharmacokinetic profile and desired therapeutic outcomes.

As with any medication, antithrombotics may have potential side effects, such as increased bleeding risk. Therefore, healthcare professionals carefully assess the patient's overall health status, including any underlying conditions, before prescribing these medications.

In conclusion, antithrombotics are a crucial subcategory of pharmaceutical APIs that play a vital role in preventing and treating thrombotic disorders. By inhibiting clot formation through various mechanisms, these medications significantly contribute to reducing the risk of serious complications associated with blood clots.


Fondaparinux sodium (Antithrombotics), classified under Anticoagulants


Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.



Fondaparinux sodium manufacturers | traders | suppliers

We have 8 companies offering Fondaparinux sodium produced in 5 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Dr. Reddy's from India, product country of origin India
  • LGM Pharma from United States, product country of origin World
  • Apino Pharma Co., Ltd. from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • BrightGene from China, product country of origin China
  • Formosa Labs from Taiwan, product country of origin Taiwan
  • Reliable Biopharm from United States, product country of origin United States

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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