Paliperidone API Manufacturers

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Located in:

India

Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

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Produced in:

China

Established in: 2011

MOQ: 100 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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India
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Slovenia

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Spain

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Malta
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Looking for Paliperidone API 144598-75-4?

Description:
Here you will find a list of producers, manufacturers and traders of Paliperidone. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Paliperidone 
Synonyms:
Invega , Paliperidone Palmitate  
Cas Number:
144598-75-4 
DrugBank number:
DB01267 
Unique Ingredient Identifier:
838F01T721

About Paliperidone

Here you will find more information about Paliperidone. Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.

Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Paliperidone is a type of Atypical antipsychotics


Atypical antipsychotics belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various mental disorders, particularly schizophrenia and bipolar disorder. These medications are designed to alleviate the symptoms of psychosis by targeting specific neuroreceptors in the brain.

Unlike traditional antipsychotics, atypical antipsychotics exhibit a different pharmacological profile, providing a more favorable side effect profile and improved efficacy. These medications primarily act on dopamine and serotonin receptors, regulating the neurotransmitter levels in the brain to restore the chemical balance.

The mechanism of action of atypical antipsychotics involves blocking dopamine receptors, particularly D2 receptors, as well as modulating serotonin receptors, notably 5-HT2A receptors. By inhibiting excessive dopamine transmission and enhancing serotonin activity, atypical antipsychotics help reduce hallucinations, delusions, and other psychotic symptoms.

Some commonly used atypical antipsychotics include risperidone, olanzapine, quetiapine, and aripiprazole. These APIs are typically formulated into oral tablets or capsules for convenient administration.

Despite their effectiveness, atypical antipsychotics may have potential side effects such as weight gain, metabolic abnormalities, sedation, and extrapyramidal symptoms. Therefore, close monitoring and individualized treatment plans are essential to ensure optimal therapeutic outcomes.

In conclusion, atypical antipsychotics are a crucial subcategory of APIs used in the treatment of mental disorders. Their distinct pharmacological profile and mechanism of action make them valuable in managing psychosis while minimizing adverse effects.


Paliperidone (Atypical antipsychotics), classified under Antipsychotics


Antipsychotics belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category used to treat psychiatric disorders such as schizophrenia, bipolar disorder, and other related conditions. These medications play a crucial role in managing symptoms associated with psychosis, including hallucinations, delusions, and disorganized thinking.

Antipsychotics work by modulating the levels of neurotransmitters in the brain, particularly dopamine and serotonin. They can be categorized into two classes: first-generation (typical) antipsychotics and second-generation (atypical) antipsychotics. Typical antipsychotics primarily target dopamine receptors, while atypical antipsychotics also affect serotonin receptors.

The pharmaceutical API category of antipsychotics includes various well-known drugs, such as haloperidol, chlorpromazine, risperidone, quetiapine, and olanzapine. These APIs are often formulated into different dosage forms, including tablets, capsules, injections, and oral suspensions, to provide flexibility in administration and patient-specific needs.

Antipsychotics offer relief from psychotic symptoms by stabilizing the imbalanced neurotransmitter activity in the brain. However, they may also have certain side effects, such as sedation, weight gain, extrapyramidal symptoms, and metabolic disturbances. It is essential for healthcare professionals to carefully monitor patients receiving antipsychotic treatment to optimize therapeutic benefits while minimizing adverse effects.

In summary, antipsychotics are a vital category of pharmaceutical APIs used to manage psychiatric disorders by modulating neurotransmitter activity in the brain. Their effectiveness in treating psychosis has made them a cornerstone of mental health treatment, providing much-needed relief to individuals suffering from these conditions.



Paliperidone manufacturers | traders | suppliers

We have 23 companies offering Paliperidone produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Morepen Laboratories Ltd. from India, product country of origin India
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Unimark Remedies from India, product country of origin India
  • KRKA from Slovenia, product country of origin Slovenia
  • Sintenovo from Spain, product country of origin Spain
  • Teva API from Israel, product country of origin Unknown
  • Torrent Pharma from India, product country of origin India
  • Gland Pharma from India, product country of origin India
  • Alkem Labs. from India, product country of origin India
  • Unichem Labs. from India, product country of origin India
  • Amino Chemicals from Malta, product country of origin Malta
  • Beijing Lunarsun Pharma from China, product country of origin China
  • Lupin from India, product country of origin India
  • Megafine Pharma (P) Ltd. from India, product country of origin India
  • Cipla from India, product country of origin India
  • Piramal Pharma Solutions from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Jubilant Generics from India, product country of origin India
  • Emcure Pharma from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Janssen Pharma from Belgium, product country of origin Unknown
  • Mylan from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India

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