Paliperidone API manufacturers
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Produced in:
Established in: 1984
MOQ: -
Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants
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Produced in:
Established in: 1991
MOQ: -
Employees: 3,500+

More than 12 GMP manufacturing facilities (EU, US, India)

Portfolio of more than 240 commercial APIs

We are experts in the cGMP production of highly potent compounds
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Produced in:
Established in: 2011
MOQ: 100 g
Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms
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Established in: 1944
MOQ: -
Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers
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Looking for Paliperidone 144598-75-4?
- Description:
- Here you will find a list of producers, manufacturers and traders of Paliperidone. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Paliperidone
- Synonyms:
- Invega , Paliperidone Palmitate
- Cas Number:
- 144598-75-4
- DrugBank number:
- DB01267
- Unique Ingredient Identifier:
- 838F01T721
About Paliperidone
Here you will find more information about Paliperidone. Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.
Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.
You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.
Paliperidone is a type of Atypical antipsychotics
Atypical antipsychotics belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various mental disorders, particularly schizophrenia and bipolar disorder. These medications are designed to alleviate the symptoms of psychosis by targeting specific neuroreceptors in the brain.
Unlike traditional antipsychotics, atypical antipsychotics exhibit a different pharmacological profile, providing a more favorable side effect profile and improved efficacy. These medications primarily act on dopamine and serotonin receptors, regulating the neurotransmitter levels in the brain to restore the chemical balance.
The mechanism of action of atypical antipsychotics involves blocking dopamine receptors, particularly D2 receptors, as well as modulating serotonin receptors, notably 5-HT2A receptors. By inhibiting excessive dopamine transmission and enhancing serotonin activity, atypical antipsychotics help reduce hallucinations, delusions, and other psychotic symptoms.
Some commonly used atypical antipsychotics include risperidone, olanzapine, quetiapine, and aripiprazole. These APIs are typically formulated into oral tablets or capsules for convenient administration.
Despite their effectiveness, atypical antipsychotics may have potential side effects such as weight gain, metabolic abnormalities, sedation, and extrapyramidal symptoms. Therefore, close monitoring and individualized treatment plans are essential to ensure optimal therapeutic outcomes.
In conclusion, atypical antipsychotics are a crucial subcategory of APIs used in the treatment of mental disorders. Their distinct pharmacological profile and mechanism of action make them valuable in managing psychosis while minimizing adverse effects.
Paliperidone (Atypical antipsychotics), classified under Antipsychotics
Antipsychotics belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category used to treat psychiatric disorders such as schizophrenia, bipolar disorder, and other related conditions. These medications play a crucial role in managing symptoms associated with psychosis, including hallucinations, delusions, and disorganized thinking.
Antipsychotics work by modulating the levels of neurotransmitters in the brain, particularly dopamine and serotonin. They can be categorized into two classes: first-generation (typical) antipsychotics and second-generation (atypical) antipsychotics. Typical antipsychotics primarily target dopamine receptors, while atypical antipsychotics also affect serotonin receptors.
The pharmaceutical API category of antipsychotics includes various well-known drugs, such as haloperidol, chlorpromazine, risperidone, quetiapine, and olanzapine. These APIs are often formulated into different dosage forms, including tablets, capsules, injections, and oral suspensions, to provide flexibility in administration and patient-specific needs.
Antipsychotics offer relief from psychotic symptoms by stabilizing the imbalanced neurotransmitter activity in the brain. However, they may also have certain side effects, such as sedation, weight gain, extrapyramidal symptoms, and metabolic disturbances. It is essential for healthcare professionals to carefully monitor patients receiving antipsychotic treatment to optimize therapeutic benefits while minimizing adverse effects.
In summary, antipsychotics are a vital category of pharmaceutical APIs used to manage psychiatric disorders by modulating neurotransmitter activity in the brain. Their effectiveness in treating psychosis has made them a cornerstone of mental health treatment, providing much-needed relief to individuals suffering from these conditions.
Paliperidone manufacturers | traders | suppliers
We have 26 companies offering Paliperidone from 6 different countries.
Get in contact with the supplier of your choice:
- Morepen Laboratories Ltd. from India
- Curia from United States
- Shandong Octagon Chemicals Limited from China
- Lupin from India
- Beijing Lunarsun Pharma from China
- Alkem Labs. from India
- Torrent Pharma from India
- Wockhardt from India
- Megafine Pharma (P) Ltd. from India
- Sintenovo from Spain
- Unichem Labs. from India
- Gland Pharma from India
- Amino Chemicals from Malta
- Teva API from Israel
- Unimark Remedies from India
- Cadila Pharma from India
- KRKA from Slovenia
- Mylan from India
- Glenmark Pharma from India
- Emcure Pharma from India
- Cipla from India
- Sun Pharma from India
- MSN Labs. from India
- Jubilant Generics from India
- Piramal Pharma Solutions from India
- Janssen Pharma from Belgium
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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