Atypical antipsychotics


Atypical antipsychotics belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various mental disorders, particularly schizophrenia and bipolar disorder. These medications are designed to alleviate the symptoms of psychosis by targeting specific neuroreceptors in the brain.

Unlike traditional antipsychotics, atypical antipsychotics exhibit a different pharmacological profile, providing a more favorable side effect profile and improved efficacy. These medications primarily act on dopamine and serotonin receptors, regulating the neurotransmitter levels in the brain to restore the chemical balance.

The mechanism of action of atypical antipsychotics involves blocking dopamine receptors, particularly D2 receptors, as well as modulating serotonin receptors, notably 5-HT2A receptors. By inhibiting excessive dopamine transmission and enhancing serotonin activity, atypical antipsychotics help reduce hallucinations, delusions, and other psychotic symptoms.

Some commonly used atypical antipsychotics include risperidone, olanzapine, quetiapine, and aripiprazole. These APIs are typically formulated into oral tablets or capsules for convenient administration.

Despite their effectiveness, atypical antipsychotics may have potential side effects such as weight gain, metabolic abnormalities, sedation, and extrapyramidal symptoms. Therefore, close monitoring and individualized treatment plans are essential to ensure optimal therapeutic outcomes.

In conclusion, atypical antipsychotics are a crucial subcategory of APIs used in the treatment of mental disorders. Their distinct pharmacological profile and mechanism of action make them valuable in managing psychosis while minimizing adverse effects.

NameCAS numberCategoryAmount of suppliersAPI market price
Amisulpride71675-85-9Atypical antipsychoticsView 28 Suppliers Average price per kg: $
Aripiprazole129722-12-9Atypical antipsychoticsView 74 Suppliers Average price per kg: $
Aripiprazole monohydrateAtypical antipsychoticsView 1 Suppliers Average price per kg: $
Asenapine65576-45-6Atypical antipsychoticsView 12 Suppliers Average price per kg: $
Blonanserin132810-10-7Atypical antipsychoticsView 4 Suppliers Average price per kg: $
Brexpiprazole913611-97-9Atypical antipsychoticsView 23 Suppliers Average price per kg: $
Cariprazine839712-12-8Atypical antipsychoticsView 8 Suppliers Average price per kg: $
Clozapine5786-21-0Atypical antipsychoticsView 25 Suppliers Average price per kg: $
Cyamemazine3546-03-0Atypical antipsychoticsView 4 Suppliers Average price per kg: $
Haloperidol52-86-8Atypical antipsychoticsView 21 Suppliers Average price per kg: $
Haloperidol decanoateAtypical antipsychoticsView 8 Suppliers Average price per kg: $
Iloperidone133454-47-4Atypical antipsychoticsView 10 Suppliers Average price per kg: $
Loxapine1977-10-2Atypical antipsychoticsView 4 Suppliers Average price per kg: $
Lumateperone313368-91-1Atypical antipsychoticsView 5 Suppliers Average price per kg: $
Lurasidone367514-87-2Atypical antipsychoticsView 36 Suppliers Average price per kg: $
Mianserin24219-97-4Atypical antipsychoticsView 5 Suppliers Average price per kg: $
Molindone7416-34-4Atypical antipsychoticsView 1 Suppliers Average price per kg: $
Olanzapine132539-06-1Atypical antipsychoticsView 56 Suppliers Average price per kg: $
Paliperidone144598-75-4Atypical antipsychoticsView 38 Suppliers Average price per kg: $
Perospirone150915-41-6Atypical antipsychoticsView 2 Suppliers Average price per kg: $
Pimavanserin706779-91-1Atypical antipsychoticsView 9 Suppliers Average price per kg: $
Pipamperone1893-33-0Atypical antipsychoticsView 1 Suppliers Average price per kg: $
Quetiapine111974-69-7Atypical antipsychoticsView 66 Suppliers Average price per kg: $
Risperidone106266-06-2Atypical antipsychoticsView 36 Suppliers Average price per kg: $
Sertindole106516-24-9Atypical antipsychoticsView 1 Suppliers Average price per kg: $
Thioridazine50-52-2Atypical antipsychoticsView 3 Suppliers Average price per kg: $
Thiothixene3313-26-6Atypical antipsychoticsView 3 Suppliers Average price per kg: $
Ziprasidone146939-27-7Atypical antipsychoticsView 20 Suppliers Average price per kg: $
Zotepine26615-21-4Atypical antipsychoticsView 1 Suppliers Average price per kg: $