Quetiapine

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Description:

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API | Excipient name:

Quetiapine 

Synonyms:

Quetiapina , Quetiapine , Quetiapine fumarate , Quetiapine hemifumarate , Quetiapinum  

Cas Number:

111974-69-7 

DrugBank number:

DB01224 

Unique Ingredient Identifier:

BGL0JSY5SI

Quetiapine is a type of Atypical antipsychotics

Atypical antipsychotics belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various mental disorders, particularly schizophrenia and bipolar disorder. These medications are designed to alleviate the symptoms of psychosis by targeting specific neuroreceptors in the brain.

Unlike traditional antipsychotics, atypical antipsychotics exhibit a different pharmacological profile, providing a more favorable side effect profile and improved efficacy. These medications primarily act on dopamine and serotonin receptors, regulating the neurotransmitter levels in the brain to restore the chemical balance.

The mechanism of action of atypical antipsychotics involves blocking dopamine receptors, particularly D2 receptors, as well as modulating serotonin receptors, notably 5-HT2A receptors. By inhibiting excessive dopamine transmission and enhancing serotonin activity, atypical antipsychotics help reduce hallucinations, delusions, and other psychotic symptoms.

Some commonly used atypical antipsychotics include risperidone, olanzapine, quetiapine, and aripiprazole. These APIs are typically formulated into oral tablets or capsules for convenient administration.

Despite their effectiveness, atypical antipsychotics may have potential side effects such as weight gain, metabolic abnormalities, sedation, and extrapyramidal symptoms. Therefore, close monitoring and individualized treatment plans are essential to ensure optimal therapeutic outcomes.

In conclusion, atypical antipsychotics are a crucial subcategory of APIs used in the treatment of mental disorders. Their distinct pharmacological profile and mechanism of action make them valuable in managing psychosis while minimizing adverse effects.

Quetiapine (Atypical antipsychotics), classified under Antipsychotics

Antipsychotics belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category used to treat psychiatric disorders such as schizophrenia, bipolar disorder, and other related conditions. These medications play a crucial role in managing symptoms associated with psychosis, including hallucinations, delusions, and disorganized thinking.

Antipsychotics work by modulating the levels of neurotransmitters in the brain, particularly dopamine and serotonin. They can be categorized into two classes: first-generation (typical) antipsychotics and second-generation (atypical) antipsychotics. Typical antipsychotics primarily target dopamine receptors, while atypical antipsychotics also affect serotonin receptors.

The pharmaceutical API category of antipsychotics includes various well-known drugs, such as haloperidol, chlorpromazine, risperidone, quetiapine, and olanzapine. These APIs are often formulated into different dosage forms, including tablets, capsules, injections, and oral suspensions, to provide flexibility in administration and patient-specific needs.

Antipsychotics offer relief from psychotic symptoms by stabilizing the imbalanced neurotransmitter activity in the brain. However, they may also have certain side effects, such as sedation, weight gain, extrapyramidal symptoms, and metabolic disturbances. It is essential for healthcare professionals to carefully monitor patients receiving antipsychotic treatment to optimize therapeutic benefits while minimizing adverse effects.

In summary, antipsychotics are a vital category of pharmaceutical APIs used to manage psychiatric disorders by modulating neurotransmitter activity in the brain. Their effectiveness in treating psychosis has made them a cornerstone of mental health treatment, providing much-needed relief to individuals suffering from these conditions.

• Menadiona, S.L. from Spain
• Vasudha Pharma Chem Ltd. from India
• DKSH from Switzerland
• Nifty Labs from India
• SUANFARMA from Spain
• Otto Brandes GmbH from Germany
• TIEFENBACHER API + Ingredients from Germany
• Sumitomo Chemical from Japan
• Astrazeneca from Sweden
• Zhejiang Hisoar from China
• SPC Life Sciences Pvt Ltd from India
• Unichem Labs. from India
• Qilu Tianhe from China
• Wanbury from India
• Inke S.A. from Spain
• Zhejiang Apeloa Tospo-Jiayuan from China
• Megafine Pharma (P) Ltd. from India
• Dishman Pharmaceuticals and Chemicals from India
• Ajinomoto from Japan
• Jubilant Generics from India
• Hikal from India
• Zhejiang Supor from China
• Ind-Swift Labs. from India
• Sandoz from Austria
• Fabbrica Italiana Sintetici (FIS) from Italy
• Zhejiang Huahai Pharma from China
• Lupin from India
• Cadila Healthcare from India
• Raks Pharma from India
• Zhejiang Hisun Pharma from China
• Indoco Remedies from India
• Torrent Pharma from India
• Hetero Labs from India
• ZCL Chemicals from India
• Fermion from Finland
• Moehs from Spain
• Alembic Pharma from India
• Hetero Drugs from India
• Dr. Reddy's from India
• Aurobindo from India
• Sun Pharma from India
• Mylan from India
• Divis Labs. from India
• Ipca Labs. from India
• Medichem from Spain
• Piramal Pharma Solutions from India

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