Butalbital | compare suppliers & send inquiries for free

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Looking for Butalbital 77-26-9?

API | Excipient name:
allylbarbital, allylbarbitone, Allylbarbituric acid, Butalbarbital, Butalbitalum, Iso-butylallylbarbituric acid, Itobarbital, Tetrallobarbital  
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About Butalbital

What makes Butalbital unique? Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from mild sedation to general anesthesia. Butalbital has a low degree of selectivity and a narrow therapeutic index. Typically indicated to manage tension (or muscle contraction) headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid, acetaminophen, aspirin, and caffeine.

There have not been clinical trials that evaluate the clinical efficacy of butalbital in migraines 1 thus it is not indicated for such condition. As with other barbiturates, butalbital carries a risk of abuse or misuse potential, intoxication, hangover, tolerance, dependence, and overdosage possibly leading to death. Butalbital‐containing analgesics can also produce a drug‐induced headache in addition to tolerance and dependence. Due to these risks, the use of butalbital-containing combination products is typically limited for use only in cases where other medications are deemed ineffective and such usage is advised to be carefully monitored.

Check who is selling Butalbital in the overview above.