Follow this page and receive
notifications about new suppliers
Dorzolamide API Manufacturers
compare suppliers & get competitive offers
Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
---|---|---|---|---|---|---|---|---|
30-Sep-2024 | (Hidden) | India | TO 'ORDER' | Taiwan (china) | DORZOLAMID... | 2 | $ @36$-7! | Check all data |
27-Sep-2024 | (Hidden) | India | M S MEDIPA... | Pakistan | PHARMACEUT... | 3.50 | $ @36$-7! | |
27-Sep-2024 | (Hidden) | India | N/A | Pakistan | PHARMACEUT... | 3 | $ @36$-7! |
Filters
Reset current filters
Type
Production region
Qualifications
Country of origin
Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
+ 0
All certificates
Distributor
Produced in:
Established in: 1997
MOQ: -
Employees: 50
GMP and GDP certified
Biotechnological research leadership and manufacturer
Extensive distribution network for product global accessibility
+ 0
All certificates
Producer
Produced in:
Established in: 2011
MOQ: 100 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
+ 0
All certificates
Distributor
+ 0
All certificates
Producer
+ 0
All certificates
Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
+ 0
All certificates
Producer
Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
How does it work?
You can register for free as long as you are registering on behalf of a legal company related to the pharmaceutical industry
Search in the search bar the product that you’re looking for. We’ll show you an overview of all available suppliers. Use the filters to select the relevant suppliers only
Have you found interesting suppliers? Then it’s time to contact them. Use the send inquiry button and send them a message. You can send for each product, 3 inquiries per week
Suppliers get notified by Pharmaoffer that they’ve received a new inquiry. They will come back to you with their questions, certificates, and offer in the chat on Pharmaoffer. We will send you an email in case of any news
Does the supplier meet your quality and commercial requirements? Then you can place the order. Just follow the steps of our order module
Looking for Dorzolamide API 120279-96-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Dorzolamide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Dorzolamide
- Synonyms:
- Dorzolamid , Dorzolamida , Dorzolamide , Dorzolamidum , Dorzolamide hydrochloride
- Cas Number:
- 120279-96-1
- DrugBank number:
- DB00869
- Unique Ingredient Identifier:
- 9JDX055TW1
About Dorzolamide
What can you use it for? Dorzolamide is a non-bacteriostatic sulfonamide derivative 2 and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances and other systemic adverse effects. First marketed in 1995 dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt 6 or in combination with timolol as Cosopt PF.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements
Dorzolamide is a type of Carbonic anhydrase(II) inhibitors
Carbonic anhydrase (CA) inhibitors are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that specifically target the enzyme carbonic anhydrase II (CAII). CAII is a zinc metalloenzyme that plays a crucial role in the regulation of acid-base balance and fluid secretion in various tissues and organs.
These inhibitors are designed to selectively bind to CAII and inhibit its enzymatic activity. By doing so, they disrupt the conversion of carbon dioxide (CO2) to bicarbonate ions (HCO3-) and protons (H+), which is a fundamental process in many physiological functions.
The inhibition of CAII has been found to be useful in the treatment of several medical conditions. One of the most common applications is in the management of glaucoma, a condition characterized by increased intraocular pressure. By inhibiting CAII in the ciliary body of the eye, these inhibitors reduce the production of aqueous humor, thus lowering the intraocular pressure.
In addition to glaucoma, CAII inhibitors have shown promise in the treatment of other disorders such as epilepsy, edema, and certain types of cancer. Their ability to modulate the pH and ion balance in tissues makes them potential therapeutic agents in a wide range of conditions.
The development of CAII inhibitors involves extensive structure-activity relationship studies and optimization of chemical properties to enhance potency, selectivity, and pharmacokinetic properties. Various structural classes of CAII inhibitors have been synthesized and tested, providing a rich pool of potential drug candidates.
In conclusion, carbonic anhydrase II inhibitors are a valuable subcategory of pharmaceutical APIs that hold promise for the treatment of various medical conditions. Continued research and development in this field may lead to the discovery of novel and effective therapies in the future.
Dorzolamide (Carbonic anhydrase(II) inhibitors), classified under Anticoagulants
Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.
There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.
Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.
While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.
In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.
Dorzolamide manufacturers | traders | suppliers
We have 10 companies offering Dorzolamide produced in 4 different countries.
Get in contact with the supplier of your choice:
- SETV Global from India, product country of origin India
- AXXO GmbH from Germany, product country of origin European Union
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Quimdis from France, product country of origin Unknown
- Indoco Remedies from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Teva API from Israel, product country of origin Unknown
- PCAS from France, product country of origin Unknown
- Micro Labs from India, product country of origin India
- Hetero Drugs from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
You can use the filters to find high-quality suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our FAQ page or use the chat box in the corner to get more information about Pharmaoffer.