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Located in:

India

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Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

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Located in:

India

Produced in:

India

Established in: 2018

MOQ: -

Employees: 200+

WHO GMP Approved sites for production

25+ years experience in manufacturing APIs for regulated markets

High quality product & superior client service

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China

Established for 17 years and a leading enterprise in China's API industry

Mature technology and advanced production equipment

Quality assurance and fast delivery

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Produced in:

United States

Established in: 1994

MOQ: -

Employees: 50+

26+ years of distribution expertise with regulatory excellence

16 worldwide locations supplying high quality ingredients

All our manufacturer partners are cGMP complaint

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Located in:

China

Produced in:

China

Established in: 1987

MOQ: -

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Produced in:

India

Established in: 1994

MOQ: -

Employees: 4,000

All our 5 plants are top notch and FDA approved

We are a backwards integrated company

We have received 24 CEP’s and 27 USDMF’s

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Produced in:

India

Established in: 1995

MOQ: -

Employees: 10000

Fermentation technology Experts

Partnerships with 1200 pharma companies in 100+ countries

US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations

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Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Looking for Dabigatran etexilate API 211915-06-9?

Description:
Here you will find a list of producers, manufacturers and traders of Dabigatran etexilate. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dabigatran etexilate 
Synonyms:
Dabigatran  
Cas Number:
211915-06-9 
DrugBank number:
DB06695 
Unique Ingredient Identifier:
2E18WX195X

About Dabigatran etexilate

Here you will find more information about Dabigatran etexilate. Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran. Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated5. In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary5. Dabigatran etexilate was approved by the FDA in 20106.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Dabigatran etexilate is a type of Direct thrombin inhibitors


Direct thrombin inhibitors are a crucial subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a vital role in anticoagulation therapy. These inhibitors are specifically designed to target and inhibit the activity of thrombin, a key enzyme involved in the blood clotting process.

Thrombin is responsible for converting fibrinogen into fibrin, the insoluble protein that forms the backbone of blood clots. By directly inhibiting thrombin, these APIs prevent the formation of blood clots, making them highly effective in the prevention and treatment of thromboembolic disorders such as deep vein thrombosis, pulmonary embolism, and stroke.

Direct thrombin inhibitors offer several advantages over traditional anticoagulants. Unlike heparin and warfarin, which target multiple coagulation factors, these inhibitors act specifically on thrombin, leading to a more predictable anticoagulant effect. Moreover, they have a rapid onset of action and do not require routine monitoring or frequent dosage adjustments.

Some commonly used direct thrombin inhibitors include dabigatran, argatroban, and bivalirudin. These APIs are typically administered orally or intravenously, depending on the specific clinical scenario. However, it is crucial to note that the use of direct thrombin inhibitors requires careful patient selection and monitoring, as they may increase the risk of bleeding.

In conclusion, direct thrombin inhibitors represent an important subcategory of pharmaceutical APIs that provide targeted and effective anticoagulation therapy. Their specific mechanism of action and favorable pharmacokinetic profiles make them valuable tools in the management of thromboembolic disorders, improving patient outcomes and reducing the risk of complications.


Dabigatran etexilate (Direct thrombin inhibitors), classified under Anticoagulants


Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.



Dabigatran etexilate manufacturers | traders | suppliers

We have 25 companies offering Dabigatran etexilate produced in 5 different countries.

Get in contact with the supplier of your choice:

  • Dr. Reddy's from India, product country of origin India
  • Gonane Pharma from India, product country of origin India
  • Xi'an ZB Biotech Co., Ltd from China, product country of origin China
  • Rochem International, Inc. from United States, product country of origin United States
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Solfyn International LLP from India, product country of origin India
  • Megafine Pharma (P) Ltd. from India, product country of origin India
  • Vasudha Pharma Chem Ltd. from India, product country of origin India
  • Apotex Pharmachem from India, product country of origin India
  • Menovo from China, product country of origin China
  • Intas Pharma from United Kingdom, product country of origin Unknown
  • Lupin from India, product country of origin India
  • Biocon from India, product country of origin India
  • Teva API from Israel, product country of origin Unknown
  • Qilu Antibiotics from China, product country of origin China
  • Piramal Pharma Solutions from India, product country of origin India
  • Jubilant Generics from India, product country of origin India
  • Jiangxi Synergy from China, product country of origin China
  • Micro Labs from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Optimus Drugs Pvt Ltd from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India
  • Boehringer Ingelheim from Germany, product country of origin Germany
  • Hetero Drugs from India, product country of origin India

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