Hydrochlorothiazide
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HIGHLIGHTED

Located in:

Switzerland

Distributor

Produced in:

United Kingdom

Established in: 1865

MOQ: -

Employees: 33,000+

Valid Regulatory support

Marketing Intelligence to stay on trend and ahead in the market

Tailored value-added services that support the increase of market potential

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

Unknown

Established in: 1886

MOQ: -

Employees: 275+

Raw materials, CMO and OTC products

Two GMP certified locations

Customisable (small-sized) packages

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  • + 0

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  • BSE/TSE

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Distributor

Produced in:

India

Established in: 1990

MOQ: -

Employees: 3,000+

More than 200,000 customers

Custom packing sizes possible

GMP and GDP certified

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  • BSE/TSE

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Produced in:

Croatia

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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  • DMF

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Located in:

China
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China
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India
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Located in:

Czech Republic

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Located in:

Italy

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Located in:

Germany

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Located in:

India

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Located in:

China
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Located in:

India

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Located in:

India
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Looking for Hydrochlorothiazide 58-93-5?

Description:
Here you will find a list of producers, manufacturers and traders of Hydrochlorothiazide. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Hydrochlorothiazide 
Synonyms:
Esidrix , Microzide  
Cas Number:
58-93-5 
DrugBank number:
DB00999 
Unique Ingredient Identifier:
0J48LPH2TH

About Hydrochlorothiazide

Learn more about Hydrochlorothiazide. Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors14 or angiotensin II receptor blockers Hydrochlorothiazide was granted FDA approval on 12 February 1959.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Hydrochlorothiazide is a type of Diuretics


Diuretics, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), are compounds commonly used in the treatment of conditions such as hypertension, congestive heart failure, and edema. Diuretics, also known as water pills, function by increasing the production of urine, thereby promoting the excretion of excess water and electrolytes from the body.

There are several types of diuretics, including thiazide diuretics, loop diuretics, and potassium-sparing diuretics. Thiazide diuretics, such as hydrochlorothiazide, work by inhibiting the reabsorption of sodium and chloride in the kidneys, leading to increased urine production. Loop diuretics, such as furosemide, act on the loop of Henle in the kidneys to block the reabsorption of sodium and chloride, resulting in a more potent diuretic effect. Potassium-sparing diuretics, like spironolactone, help retain potassium in the body while still promoting diuresis.

These diuretic APIs are widely used in the pharmaceutical industry to formulate medications that effectively manage fluid retention and related conditions. They are available in various forms, including tablets, capsules, and intravenous formulations. Diuretics are often prescribed as part of combination therapies to enhance their effectiveness and minimize adverse effects.

It is important to note that the use of diuretics should be closely monitored by healthcare professionals due to potential side effects such as electrolyte imbalances, dehydration, and hypotension. Proper dosage and patient-specific considerations are crucial to ensure optimal therapeutic outcomes.

In conclusion, diuretics are a vital subcategory of pharmaceutical APIs used to treat conditions characterized by fluid retention. Their mechanisms of action vary, but they all facilitate increased urine production, assisting the body in eliminating excess fluids. The proper use of diuretics, in combination with medical supervision, can effectively manage various cardiovascular and renal conditions.


Hydrochlorothiazide (Diuretics), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Hydrochlorothiazide manufacturers | traders | suppliers

We have 23 companies offering Hydrochlorothiazide from 7 different countries.

Get in contact with the supplier of your choice:

  • DKSH from Switzerland
  • TIEFENBACHER API + Ingredients from Germany
  • Caesar & Loretz GmbH (CAELO) from Germany
  • Fagron Industry from Belgium
  • Otto Brandes GmbH from Germany
  • Changzhou Pharmaceutical Factory from China
  • Changzhou Pharma from China
  • Unichem Labs. from India
  • PLIVA from Czech Republic
  • Suzhou Lixin from China
  • Cambrex from Italy
  • Blue Circle Organics from India
  • Valens Molecules from India
  • Arevipharma from Germany
  • Flamma from Italy
  • Cadila Healthcare from India
  • Amoli Organics from India
  • Medinex Labs. from India
  • Teva API from Israel
  • Ipca Labs. from India
  • Shaoxing Hantai Pharma from China
  • Aurobindo from India
  • Alembic Pharma from India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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