Mannitol API Manufacturers

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TOP RANKING

Located in:

Netherlands

Produced in:

France

Established in: 1968

MOQ: 5 kg

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • GMP

  • BSE/TSE

  • MSDS

TOP RANKING

Located in:

United States

Produced in:

China

Established in: 1991

MOQ: -

Employees: 50+

High quality APIs with competitive pricing

Worldwide network of GMP manufacturers

DMF support worldwide with unparalleled customer service

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • GMP

  • CoA

  • MSDS

  • BSE/TSE

HIGHLIGHTED

Located in:

Japan

Produced in:

Japan

Established in: 1922

MOQ: -

Employees: 2400+

Leading Japanese manufacturer with over 100 years of history

Offices in Japan, US, China, and Germany, factory in Japan

Offer GMP complied products and CRO service

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

Produced in:

Unknown

Established in: 1886

MOQ: -

Employees: 275+

Raw materials, CMO and OTC products

Two GMP certified locations

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

Distributor

Produced in:

World

Established in: 1997

MOQ: -

Employees: 50

GMP and GDP certified

Biotechnological research leadership and manufacturer

Extensive distribution network for product global accessibility

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • GMP

  • CoA

  • MSDS

  • ISO9001

Located in:

Italy

Produced in:

Italy

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • coa

  • GMP

Located in:

Japan

Produced in:

Japan

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • JDMF

  • CoA

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • WC

  • CoA

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

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Looking for Mannitol API 69-65-8?

Description:
Here you will find a list of producers, manufacturers and distributors of Mannitol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Mannitol 
Synonyms:
D-Mannitol , e 421 , Fraxinine , Manitol , Manna Sugar , Mannit , Mannite , Mannitol , Mannitolum , Osmitrol  
Cas Number:
69-65-8 
DrugBank number:
DB00742 
Unique Ingredient Identifier:
3OWL53L36A

About Mannitol

Learn more about Mannitol. Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced.

Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established;the promotion of urinary excretion of toxic substances;as an Antiglaucoma agent;and as a renal function diagnostic aid. On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for this indication under the name BRONCHITOL® by Chiesi USA Inc.

Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

Mannitol is a type of Diuretics


Diuretics, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), are compounds commonly used in the treatment of conditions such as hypertension, congestive heart failure, and edema. Diuretics, also known as water pills, function by increasing the production of urine, thereby promoting the excretion of excess water and electrolytes from the body.

There are several types of diuretics, including thiazide diuretics, loop diuretics, and potassium-sparing diuretics. Thiazide diuretics, such as hydrochlorothiazide, work by inhibiting the reabsorption of sodium and chloride in the kidneys, leading to increased urine production. Loop diuretics, such as furosemide, act on the loop of Henle in the kidneys to block the reabsorption of sodium and chloride, resulting in a more potent diuretic effect. Potassium-sparing diuretics, like spironolactone, help retain potassium in the body while still promoting diuresis.

These diuretic APIs are widely used in the pharmaceutical industry to formulate medications that effectively manage fluid retention and related conditions. They are available in various forms, including tablets, capsules, and intravenous formulations. Diuretics are often prescribed as part of combination therapies to enhance their effectiveness and minimize adverse effects.

It is important to note that the use of diuretics should be closely monitored by healthcare professionals due to potential side effects such as electrolyte imbalances, dehydration, and hypotension. Proper dosage and patient-specific considerations are crucial to ensure optimal therapeutic outcomes.

In conclusion, diuretics are a vital subcategory of pharmaceutical APIs used to treat conditions characterized by fluid retention. Their mechanisms of action vary, but they all facilitate increased urine production, assisting the body in eliminating excess fluids. The proper use of diuretics, in combination with medical supervision, can effectively manage various cardiovascular and renal conditions.


Mannitol (Diuretics), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Mannitol manufacturers | traders | suppliers

We have 9 companies offering Mannitol produced in 7 different countries.

Get in contact with the supplier of your choice:

  • Duchefa Farma B.V. from Netherlands, product country of origin France
  • Pharm Rx Chemical Corp from United States, product country of origin China
  • Fujifilm Wako Pure Chemical Corporation from Japan, product country of origin Japan
  • Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
  • AXXO GmbH from Germany, product country of origin World
  • Cargill S.R.L. from Italy, product country of origin Italy
  • B Food Science from Japan, product country of origin Japan
  • Bright Moon Seaweed Group from China, product country of origin China
  • Chemizo Enterprise from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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