Empagliflozin API Manufacturers & Suppliers

Looking for Empagliflozin API 864070-44-0?

Description:

Here you will find a list of producers, manufacturers and distributors of Empagliflozin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Empagliflozin 

Cas Number:

864070-44-0 

DrugBank number:

DB09038 

Unique Ingredient Identifier:

HDC1R2M35U

Empagliflozin is a type of SGLT2-inhibitors

SGLT2 inhibitors, short for Sodium-Glucose Co-Transporter 2 inhibitors, belong to the pharmaceutical API subcategory utilized in the treatment of type 2 diabetes mellitus (T2DM). These innovative drugs target the SGLT2 protein responsible for reabsorbing glucose in the kidneys, resulting in increased urinary glucose excretion.

By inhibiting SGLT2, these drugs effectively lower blood glucose levels and improve glycemic control in patients with T2DM. This mechanism of action is independent of insulin secretion or sensitivity, making SGLT2 inhibitors an attractive option for individuals who are resistant to or cannot tolerate other diabetes medications.

Some commonly prescribed SGLT2 inhibitors include canagliflozin, dapagliflozin, and empagliflozin. These pharmaceutical APIs are typically formulated into oral tablets, making them convenient for patient administration.

Clinical studies have demonstrated the effectiveness of SGLT2 inhibitors in reducing HbA1c levels, body weight, and blood pressure in patients with T2DM. Additionally, these medications have shown potential cardiovascular benefits, including a decreased risk of cardiovascular events.

However, it is important to note that SGLT2 inhibitors are not suitable for everyone, and their use should be carefully considered in patients with renal impairment or a history of ketoacidosis. Adverse effects may include genitourinary infections and increased risk of dehydration.

Overall, SGLT2 inhibitors are a promising class of pharmaceutical APIs that offer an innovative approach to managing T2DM by targeting renal glucose reabsorption. Ongoing research and development in this field aim to further optimize the therapeutic potential of SGLT2 inhibitors and improve patient outcomes.

Empagliflozin (SGLT2-inhibitors), classified under Anti-diabetics

Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.

• Shandong Boyuan from China, product country of origin China
• Morepen Laboratories Ltd. from India, product country of origin India
• Polpharma from Poland, product country of origin Poland
• Rochem International, Inc. from United States, product country of origin United States
• Senova Technology Co., Ltd. from China, product country of origin China
• Vonage Pharma (Former Pluvia Endo) from Turkey, product country of origin Turkey
• Apino Pharma Co., Ltd. from China, product country of origin China
• Global Pharma Tek from India, product country of origin India
• Sinoway industrial Co.,Ltd from China, product country of origin China
• Tianjin Pharmacn Medical Technology Co., ltd from China, product country of origin China
• AXXO GmbH from Germany, product country of origin World
• ACE Japan from Japan, product country of origin Japan
• Amino Chemicals from Malta, product country of origin Malta
• TAPI from Israel, product country of origin Israel
• ALP PHARM from China, product country of origin China
• Laurus Labs from India, product country of origin India
• Zhejiang Hongyuan from China, product country of origin China
• Solfyn International LLP from India, product country of origin China
• Fuxing Long Rui Pharma from China, product country of origin China
• Hikal from India, product country of origin India
• Dr. Reddy's from India, product country of origin India
• Bidachem from Italy, product country of origin Italy
• Honour Lab from India, product country of origin India
• Jiangxi Aifeimu Technology Co Ltd from China, product country of origin China
• Beijing Huikang Boyuan from China, product country of origin China
• Shaoxing Hantai Pharma from China, product country of origin China
• Boehringer Ingelheim from Germany, product country of origin Germany
• MSN Life Sciences from India, product country of origin India
• Mylan from India, product country of origin India
• Lupin from India, product country of origin India
• Sun Pharma from India, product country of origin India
• Cipla from India, product country of origin India
• ZCL Chemicals from India, product country of origin India

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