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Hydroxyethylcellulose 250 API Manufacturers & Suppliers

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API | Excipient name:

Hydroxyethylcellulose 250 

Synonyms:

Natrosol 250  

Cas Number:

9004-62-0 

Hydroxyethylcellulose 250 is a type of Hypromellose

Hypromellose, also known as hydroxypropyl methylcellulose (HPMC), is a widely used pharmaceutical active pharmaceutical ingredient (API) belonging to the subcategory of pharmaceutical excipients. It is a non-ionic cellulose ether derived from natural polymer cellulose, making it a safe and biocompatible compound for pharmaceutical applications.

Hypromellose is primarily utilized in the pharmaceutical industry as a thickening agent, binder, film former, and sustained-release matrix material. It is commonly employed in the formulation of oral solid dosage forms such as tablets and capsules. Due to its hydrophilic nature, hypromellose aids in enhancing the dissolution rate and bioavailability of poorly soluble drugs.

One of the key advantages of hypromellose is its ability to modify the drug release profile. By adjusting the viscosity and concentration of hypromellose in the formulation, pharmaceutical manufacturers can achieve controlled and extended drug release, ensuring optimal therapeutic efficacy and patient compliance. This makes hypromellose a preferred choice for the development of sustained-release and controlled-release dosage forms.

In addition, hypromellose offers excellent film-forming properties, making it suitable for coating tablets to improve their appearance, protect the active ingredient from degradation, and facilitate ease of swallowing. It also acts as a binder, imparting cohesive properties to powdered drug formulations, allowing for the production of compressed tablets with adequate hardness and mechanical strength.

Overall, hypromellose is a versatile and valuable API subcategory in the pharmaceutical industry, providing numerous benefits such as enhanced drug solubility, controlled release, and improved formulation characteristics for various oral dosage forms.

Hydroxyethylcellulose 250 (Hypromellose), classified under Additives

Additives in the pharmaceutical API category refer to a group of chemical substances that are incorporated into pharmaceutical products to enhance their stability, functionality, or performance. These additives play a crucial role in ensuring the quality, safety, and efficacy of medications.

One common type of additive used in pharmaceuticals is preservatives. Preservatives are added to prevent microbial growth and maintain the integrity of the product throughout its shelf life. They help to safeguard against contamination and maintain the potency of the active pharmaceutical ingredient (API). Some commonly used preservatives include benzyl alcohol, phenol, and parabens.

Another important group of additives is antioxidants. Antioxidants are added to pharmaceutical formulations to prevent or delay the oxidation of APIs, which can lead to degradation and loss of potency. Examples of antioxidants commonly used in pharmaceuticals include ascorbic acid (vitamin C) and tocopherols (vitamin E).

In addition to preservatives and antioxidants, other additives like flavorings, colorants, and sweeteners may be incorporated into pharmaceutical products to improve their palatability and patient acceptability.

It is crucial to note that the use of additives in pharmaceuticals is strictly regulated by health authorities to ensure their safety and efficacy. Manufacturers must comply with stringent quality control standards and guidelines to guarantee the proper use and appropriate levels of additives in pharmaceutical products.

Overall, additives play a vital role in the pharmaceutical industry by enhancing the stability, functionality, and patient acceptability of medications. Their careful selection and incorporation contribute to the overall quality and effectiveness of pharmaceutical products.