Ketoconazole | compare suppliers & send inquiries for free
Looking for Ketoconazole 65277-42-1?
Why are people looking for Ketoconazole? Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus1 Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. At this time it was considered a significant improvement over previous antifungals, miconazole and clotrimazole, due to its broad spectrum and good absorption. However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis These effects combined with waning efficacy led to its eventual replacement by triazole agents, fluconazole, itraconazole, voriconazole, and posaconazole.
Ketoconazole and its predecessor clotrimazole continue to be used in topical formulations.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Ketoconazole manufacturers | traders | suppliers
We have 13 companies offering Ketoconazole from 5 different countries.
Get in contact with the supplier of your choice:
- Duchefa Farma B.V. from Netherlands
- TIEFENBACHER API + Ingredients from Germany
- Aarti Drugs from India
- Piramal Pharma Solutions from India
- Shaoxing Hantai Pharma from China
- Prachi Pharmaceuticals from India
- Esteve Quimica from Spain
- Unnati Pharmaceuticals Pvt Ltd from India
- Sharon Bio-Medicine from India
- Quimica Sintetica from Spain
- Derivados Quimicos from Spain
- Nanjing Baijingyu from China
- Gufic Biosciences from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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