Ezetimibe

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Description:

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API | Excipient name:

Ezetimibe 

Synonyms:

Ezedoc , Ezetimiba , Ezetimibum , Ezetrol , Zetia  

Cas Number:

163222-33-1 

DrugBank number:

DB00973 

Unique Ingredient Identifier:

EOR26LQQ24

Ezetimibe is a type of Lipid-lowering agents

Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.

One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.

Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.

Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.

Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.

It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.

• DKSH from Switzerland
• SENOVA Technology Co., Ltd. from China
• Shandong Octagon Chemicals Limited from China
• TIEFENBACHER API + Ingredients from Germany
• Otto Brandes GmbH from Germany
• Menovo from China
• Teva API from Israel
• Lupin from India
• Hanmi Fine Chemical from South Korea
• Signa from Mexico
• Themis Medicare from India
• KRKA from Slovenia
• Aquatic Remedies Pvt Ltd from India
• Wuhan ZhongYou  from China
• Ind-Swift Labs. from India
• Kolon Life Science from South Korea
• GVK Biosciences Pvt Ltd from India
• Nantong Chanyoo from China
• Beijing Hope from China
• Changzhou Pharma from China
• Jiangsu Hansyn Pharma from China
• WATERSTONE PHARMACEUTICALS from China
• Raks Pharma from India
• Glenmark Pharma from India
• Hetero Labs from India
• Aurobindo from India
• MSN Labs. from India
• Cipla from India
• Mylan from India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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