Ezetimibe
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HIGHLIGHTED

Located in:

Switzerland

Distributor

Produced in:

United Kingdom

Established in: 1865

MOQ: -

Employees: 33,000+

Valid Regulatory support

Marketing Intelligence to stay on trend and ahead in the market

Tailored value-added services that support the increase of market potential

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 1 g

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

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Produced in:

China

Established in: 2011

MOQ: 1 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

China

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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Located in:

China

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Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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India

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Looking for Ezetimibe 163222-33-1?

Description:
Here you will find a list of producers, manufacturers and traders of Ezetimibe. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Ezetimibe 
Synonyms:
Ezedoc , Ezetimiba , Ezetimibum , Ezetrol , Zetia  
Cas Number:
163222-33-1 
DrugBank number:
DB00973 
Unique Ingredient Identifier:
EOR26LQQ24

About Ezetimibe

Why are professionals looking for Ezetimibe? Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids.

Ask the supplier for a certificate of analysis to find out more about the quality of Ezetimibe.

Ezetimibe is a type of Lipid-lowering agents


Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.

One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.

Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.

Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.

Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.

It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.

Ezetimibe manufacturers | traders | suppliers

We have 29 companies offering Ezetimibe from 7 different countries.

Get in contact with the supplier of your choice:

  • DKSH from Switzerland
  • SENOVA Technology Co., Ltd. from China
  • Shandong Octagon Chemicals Limited from China
  • TIEFENBACHER API + Ingredients from Germany
  • Otto Brandes GmbH from Germany
  • Menovo from China
  • Teva API from Israel
  • Lupin from India
  • Hanmi Fine Chemical from South Korea
  • Signa from Mexico
  • Themis Medicare from India
  • KRKA from Slovenia
  • Aquatic Remedies Pvt Ltd from India
  • Wuhan ZhongYou  from China
  • Ind-Swift Labs. from India
  • Kolon Life Science from South Korea
  • GVK Biosciences Pvt Ltd from India
  • Nantong Chanyoo from China
  • Beijing Hope from China
  • Changzhou Pharma from China
  • Jiangsu Hansyn Pharma from China
  • WATERSTONE PHARMACEUTICALS from China
  • Raks Pharma from India
  • Glenmark Pharma from India
  • Hetero Labs from India
  • Aurobindo from India
  • MSN Labs. from India
  • Cipla from India
  • Mylan from India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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