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Ezetimibe API Manufacturers
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Distributor
Produced in:
Established in: 1994
MOQ: -
Employees: 50+
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26+ years of distribution expertise with regulatory excellence
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16 worldwide locations supplying high quality ingredients
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All our manufacturer partners are cGMP complaint
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Distributor
Produced in:
Established in: 1987
MOQ: -
Employees: 50+
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Passed ISO9001:2015 and SGS audit
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Provide one-stop CDMO service from R&D to production
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Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Producer
Produced in:
Established in: 2011
MOQ: 1 g
Employees: 10+
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Fast Response and Good Communication
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Willingness To Start From Small
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Flexible Payment Terms
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Producer
Produced in:
Established in: 2013
MOQ: 1 g
Employees: 25+
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ISO9001 certified
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Drug R&D center (in Hangzhou)
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From lab scale (mg/g) to commercial scale (kgs/tons)
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Producer
Produced in:
![Unknown Unknown](/build/images/flags/un-512px.cca7cda3.png)
Established in: 1944
MOQ: -
Employees: 4,000
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14 international API plant sites
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Portfolio of 350+ APIs
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Teva is among the world’s largest generic drug/API manufacturers
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Distributor
Produced in:
Established in: 1923
MOQ: 25 kg
Employees: 20+
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Service-oriented company
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Global supply chain resilience
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Support of your new projects from start to commercial realisation
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Distributor
Produced in:
![Unknown Unknown](/build/images/flags/un-512px.cca7cda3.png)
Established in: 1963
MOQ: -
Employees: 800+
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World’s 1st exclusive API distributor
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Portfolio of 600+ APIs
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>250 clients in Europe
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Looking for Ezetimibe API 163222-33-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Ezetimibe. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Ezetimibe
- Synonyms:
- Ezedoc , Ezetimiba , Ezetimibum , Ezetrol , Zetia
- Cas Number:
- 163222-33-1
- DrugBank number:
- DB00973
- Unique Ingredient Identifier:
- EOR26LQQ24
About Ezetimibe
Why are professionals looking for Ezetimibe? Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids.
Ask the supplier for a certificate of analysis to find out more about the quality of Ezetimibe.
Ezetimibe is a type of Lipid-lowering agents
Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.
One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.
Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.
Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.
Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.
It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.
Ezetimibe manufacturers | traders | suppliers
We have 27 companies offering Ezetimibe produced in 7 different countries.
Get in contact with the supplier of your choice:
- Rochem International, Inc. from United States, product country of origin United States
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Senova Technology Co., Ltd. from China, product country of origin China
- Raks Pharma from India, product country of origin India
- Teva API from Israel, product country of origin Unknown
- Changzhou Pharma from China, product country of origin China
- Otto Brandes GmbH from Germany, product country of origin China
- Aquatic Remedies Pvt Ltd from India, product country of origin India
- Signa from Mexico, product country of origin Mexico
- Themis Medicare from India, product country of origin India
- Ind-Swift Labs. from India, product country of origin India
- Wuhan ZhongYou from China, product country of origin China
- GVK Biosciences Pvt Ltd from India, product country of origin India
- Jiangsu Hansyn Pharma from China, product country of origin China
- Hanmi Fine Chemical from South Korea, product country of origin South Korea
- WATERSTONE PHARMACEUTICALS from China, product country of origin China
- Nantong Chanyoo from China, product country of origin China
- Kolon Life Science from South Korea, product country of origin South Korea
- KRKA from Slovenia, product country of origin Slovenia
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Menovo from China, product country of origin China
- Mylan from India, product country of origin India
- MSN Labs. from India, product country of origin India
- Lupin from India, product country of origin India
- Hetero Labs from India, product country of origin India
- Cipla from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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