Linaclotide API Manufacturers

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TOP RANKING

Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

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Produced in:

China

Established in: 2011

MOQ: 1 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

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  • CoA

  • BSE/TSE

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  • WC

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Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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  • CEP

  • FDA

  • DMF

  • + 0

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  • BSE/TSE

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Produced in:

United States

Established in: 1994

MOQ: -

Employees: 50+

26+ years of distribution expertise with regulatory excellence

16 worldwide locations supplying high quality ingredients

All our manufacturer partners are cGMP complaint

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Located in:

Czech Republic

Producer

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  • CoA

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Replies slower than most

Located in:

Germany
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Located in:

China
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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Located in:

India

Producer

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Located in:

Sweden
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Located in:

India
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  • WC

  • CoA

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Looking for Linaclotide API 851199-59-2?

Description:
Here you will find a list of producers, manufacturers and traders of Linaclotide. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Linaclotide 
Synonyms:
 
Cas Number:
851199-59-2 
DrugBank number:
DB08890 
Unique Ingredient Identifier:
N0TXR0XR5X

About Linaclotide

Here is a short description about Linaclotide. Linaclotide is an orally administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids. The protein sequence is as follows: Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr. There are three disulfide bonds which are located between Cys1 and Cys6;between Cys2 and Cys10;and between Cys5 and Cys1. FDA approved on August 30, 2012.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Linaclotide is a type of Motility inhibitors


Motility inhibitors are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that are used to regulate and control the movement of the gastrointestinal tract. These inhibitors play a crucial role in treating conditions such as irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and other gastrointestinal disorders.

Motility inhibitors work by blocking the action of certain neurotransmitters and receptors in the gastrointestinal tract, thereby reducing the frequency and intensity of contractions in the smooth muscles. This leads to a decrease in the speed of food passage through the digestive system, providing relief from symptoms like abdominal pain, bloating, and diarrhea.

One commonly used motility inhibitor is metoclopramide, which acts by inhibiting dopamine receptors in the gastrointestinal tract. It enhances the contractions of the stomach and small intestine while relaxing the muscles of the pyloric sphincter, thus improving gastric emptying and reducing reflux.

Another important motility inhibitor is loperamide, which works by slowing down the muscular contractions of the intestines. It is commonly used to treat diarrhea by increasing the time it takes for stool to move through the digestive system.

Motility inhibitors are available in various forms, including tablets, capsules, and oral suspensions. They are generally well-tolerated, but like any medication, they can have side effects such as drowsiness, dizziness, and constipation.

In summary, motility inhibitors are an essential subcategory of pharmaceutical APIs used to manage gastrointestinal disorders by regulating the movement of the digestive tract. They provide relief from symptoms and improve overall digestive function, enhancing the quality of life for individuals suffering from these conditions.


Linaclotide (Motility inhibitors), classified under Gastrointestinal Agents


Gastrointestinal Agents belong to the pharmaceutical API category that focuses on treating disorders and ailments related to the digestive system. These agents play a crucial role in addressing various gastrointestinal conditions, such as acid reflux, ulcers, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD).

One of the key types of gastrointestinal agents is proton pump inhibitors (PPIs), which work by reducing the production of stomach acid. PPIs help in treating conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. Another essential class of agents is antacids, which neutralize excessive stomach acid, providing relief from heartburn and indigestion.

Gastrointestinal agents also include antispasmodics that alleviate abdominal cramps and spasms associated with conditions like IBS. These drugs work by relaxing the smooth muscles of the digestive tract. Additionally, there are drugs categorized as laxatives that aid in relieving constipation by promoting bowel movements.

Moreover, certain gastrointestinal agents act as antiemetics, effectively reducing nausea and vomiting. These drugs are particularly useful for patients undergoing chemotherapy or experiencing motion sickness.

Pharmaceutical companies develop and manufacture a wide range of gastrointestinal agents in various forms, including tablets, capsules, suspensions, and injections. These agents are typically formulated using active pharmaceutical ingredients (APIs) and other excipients to ensure their efficacy and safety.

In conclusion, gastrointestinal agents form a vital category of pharmaceutical APIs, providing relief from digestive disorders and improving overall gastrointestinal health. The availability of diverse agents catering to different conditions ensures that patients can receive targeted treatment for their specific gastrointestinal needs.



Linaclotide manufacturers | traders | suppliers

We have 11 companies offering Linaclotide produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Rochem International, Inc. from United States, product country of origin United States
  • PLIVA from Czech Republic, product country of origin Croatia
  • Corden Pharma from Germany, product country of origin United States
  • Hybio Pharmaceutical from China, product country of origin China
  • Teva API from Israel, product country of origin Unknown
  • Sun Pharma from India, product country of origin India
  • Polypeptide Labs from Sweden, product country of origin Unknown
  • MSN Life Sciences from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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