Gastrointestinal Agents


Gastrointestinal Agents belong to the pharmaceutical API category that focuses on treating disorders and ailments related to the digestive system. These agents play a crucial role in addressing various gastrointestinal conditions, such as acid reflux, ulcers, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD).

One of the key types of gastrointestinal agents is proton pump inhibitors (PPIs), which work by reducing the production of stomach acid. PPIs help in treating conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. Another essential class of agents is antacids, which neutralize excessive stomach acid, providing relief from heartburn and indigestion.

Gastrointestinal agents also include antispasmodics that alleviate abdominal cramps and spasms associated with conditions like IBS. These drugs work by relaxing the smooth muscles of the digestive tract. Additionally, there are drugs categorized as laxatives that aid in relieving constipation by promoting bowel movements.

Moreover, certain gastrointestinal agents act as antiemetics, effectively reducing nausea and vomiting. These drugs are particularly useful for patients undergoing chemotherapy or experiencing motion sickness.

Pharmaceutical companies develop and manufacture a wide range of gastrointestinal agents in various forms, including tablets, capsules, suspensions, and injections. These agents are typically formulated using active pharmaceutical ingredients (APIs) and other excipients to ensure their efficacy and safety.

In conclusion, gastrointestinal agents form a vital category of pharmaceutical APIs, providing relief from digestive disorders and improving overall gastrointestinal health. The availability of diverse agents catering to different conditions ensures that patients can receive targeted treatment for their specific gastrointestinal needs.

NameCAS numberCategoryAmount of suppliers
Acetoxolone6277-14-1Gastrointestinal Agents0
Alginic acid9005-32-7Antacids3
Alicaforsen185229-68-9Gastrointestinal Agents0
Alloin8015-61-0Gastrointestinal Agents0
Almasilate71205-22-6Gastrointestinal Agents0
Aloglutamol13755-41-4Gastrointestinal Agents0
Aluminium phosphate7784-30-7Gastrointestinal Agents0
Aluminum hydroxide21645-51-2Antacids12
Aluminum magnesium hydroxide39366-43-3Antacids1
Alvimopan156053-89-3Motility inhibitors3
Anethole trithione532-11-6Gastrointestinal Agents0
Azintamide2216711-16-9Other gastrointestinal agents1
Benzilone16175-92-1Gastrointestinal Agents0
Bisacodyl603-50-9Laxatives17
Blond psyllium seedLaxatives1
Calcium silicate1344-95-2Gastrointestinal Agents0
Carbutamide339-43-5Gastrointestinal Agents0
Caroverine23465-76-1Gastrointestinal Agents0
Castor oil8001-79-4Gastrointestinal Agents0
Castor oil hydrogenatedLaxatives2
Chenodeoxycholic acid474-25-9Bile acid preparations6
Chlorbenzoxamine522-18-9Gastrointestinal Agents0
Cholestyramine11041-12-6Bile acid sequestrants7
Cholic acid81-25-4Bile acid preparations8
Cimetidine51481-61-9H2 antagonists14
Cinitapride66564-14-5Prokinetics4
Cisapride81098-60-4Prokinetics4
Clebopride55905-53-8Gastrointestinal Agents0
Clobenzorex13364-32-4Gastrointestinal Agents0
Colesevelam182815-43-6Bile acid sequestrants7
Colesevelam-Hydrochloride182815-44-7Bile acid sequestrants1
Colestilan chloride95522-45-5Gastrointestinal Agents0
Colestipol26658-42-4Bile acid sequestrants2
Cyclobutyrol512-16-3Gastrointestinal Agents0
DL-dimyristoylphosphatidylcholine18656-38-7Gastrointestinal Agents0
DL-dimyristoylphosphatidylglycerol61361-72-6Gastrointestinal Agents0
Dehydrocholic AcidBile acid preparations2
Dexlansoprazole138530-94-6Gastrointestinal Agents0
DexlanzoprazoleProton pump inhibitors1
Dexrabeprazole177795-60-7Gastrointestinal Agents0
Diisopromine5966-41-6Gastrointestinal Agents0
Docusate Sodium577-11-7Laxatives2
Domperidone57808-66-9Prokinetics21
Domperidone maleate99497-03-7Prokinetics11
Ecabet33159-27-2Mucosa protectants4
Emetonium iodide5982-52-5Gastrointestinal Agents0
Enprostil73121-56-9Gastrointestinal Agents0
Epomediol1310101-21-3Gastrointestinal Agents0
Esomeprazole119141-88-7Proton pump inhibitors56
Esomeprazole magnesium trihydrateProton pump inhibitors32
Etilamfetamine457-87-4Gastrointestinal Agents0
Famotidine76824-35-6H2 antagonists36
Fenpiprane3540-95-2Gastrointestinal Agents0
Fenpiverinium258329-46-3Gastrointestinal Agents0
Fosdenopterin150829-29-1Gastrointestinal Agents0
Fosfructose488-69-7Gastrointestinal Agents0
FrangulaLaxatives1
Gefarnate51-77-4Gastrointestinal Agents0
Givosiran1639325-43-1Gastrointestinal Agents0
GlycerinLaxatives8
Hydrotalcite12304-65-3Gastrointestinal Agents0
Hymecromone90-33-5Bile acid preparations2
Idursulfase beta1271734-34-9Gastrointestinal Agents0
Imeglimin775351-65-0Gastrointestinal Agents0
Inosine 5'-sulfate70023-32-4Gastrointestinal Agents0
Inositol87-89-8Gastrointestinal Agents1
Ipragliflozin761423-87-4Gastrointestinal Agents1
Isatoic anhydride118-48-9H2 antagonists1
Itopride122898-67-3Gastrointestinal Agents13
Karaya gum9000-36-6Gastrointestinal Agents0
Konjac mannan37220-17-0Gastrointestinal Agents0
Lactitol585-86-4Gastrointestinal Agents0
Lactulose4618-18-2Laxatives9
Lactulose liquid4618-18-2Laxatives7
Lansoprazole103577-45-3Proton pump inhibitors56
Lesogaberan344413-67-8Gastrointestinal Agents0
Linaclotide851199-59-2Motility inhibitors16
Lonafarnib193275-84-2Gastrointestinal Agents0
Lubiprostone136790-76-6Gastrointestinal Agents10
Lumasiran1834610-13-7Gastrointestinal Agents0
Luseogliflozin898537-18-3Gastrointestinal Agents1
Macrogol 1000Laxatives3
Macrogol 1500Laxatives4
Macrogol 3000Laxatives2
Macrogol 3350Laxatives6
Macrogol 400Laxatives5
Macrogol 4000Laxatives9
Macrogol 600Laxatives1
Macrogol 6000Laxatives4
Macrogol 8000Laxatives2
Magaldrate74978-16-8Antacids6
Magnesium peroxide14452-57-4Gastrointestinal Agents0
Magnesium silicate1343-88-0Gastrointestinal Agents0
MannaLaxatives1
Maralixibat716313-53-0Gastrointestinal Agents0
Metahexamide565-33-3Gastrointestinal Agents0
Metandienone72-63-9Gastrointestinal Agents0
Metenolone153-00-4Gastrointestinal Agents0
Methyl cellulose9004-67-5Laxatives1
Methylatropine31610-87-4Gastrointestinal Agents0
Mosapride112885-41-3Gastrointestinal Agents0
Moxaverine10539-19-2Gastrointestinal Agents0
N-methylnicotinamide114-33-0Gastrointestinal Agents0
Niperotidine84845-75-0Gastrointestinal Agents0
Nizatidine76963-41-2H2 antagonists5
Odevixibat501692-44-0Gastrointestinal Agents0
Olaflur6818-37-7Gastrointestinal Agents0
Omeprazole73590-58-6Proton pump inhibitors65
Omeprazole Magnesium95382-33-5Proton pump inhibitors23
Omeprazole sodium95510-70-6Proton pump inhibitors15
Ox BileBile acid preparations3
Oxabolone cipionate1254-35-9Gastrointestinal Agents0
Oxyphenisatin acetate115-33-3Gastrointestinal Agents0
PEG 30025322-68-3Laxatives5
PEG 335025322-68-3Laxatives1
Pantoprazole102625-70-7Proton pump inhibitors77
Pegunigalsidase alfa1644392-61-9Gastrointestinal Agents0
Pentaerithrityl115-77-5Gastrointestinal Agents0
Penthienate22064-27-3Gastrointestinal Agents0
Phenolphthalein77-09-8Laxatives3
Picosulfuric acid10040-34-3Laxatives15
Polaprezinc107667-60-7Other gastrointestinal agents6
Poldine596-50-9Gastrointestinal Agents0
Praliciguat1628730-49-3Gastrointestinal Agents0
Prifinium10236-81-4Gastrointestinal Agents0
Proxazole5696-09-3Gastrointestinal Agents0
Prucalopride179474-81-8Laxatives7
Quinbolone2487-63-0Gastrointestinal Agents0
Rabeprazole117976-89-3Proton pump inhibitors46
Rabeprazole Sodium117976-90-6Gastrointestinal Agents1
Ranitidine66357-35-5H2 antagonists17
Rebamipide90098-04-7Gastrointestinal Agents22
Roxatidine acetate78628-28-1H2 antagonists2
Salcaprozate Sodium (SNAC) - Non-API203787-91-1Other gastrointestinal agents4
Senna fruit alexandrieLaxatives1
Senna fruit tinnevellyLaxatives1
Senna glycosideLaxatives8
Senna leafLaxatives1
Senna leaves cutLaxatives1
Simethicone8050-81-5Antiflatulents15
Sodium alginateMucosa protectants6
Sodium cellulose phosphate9038-41-9Gastrointestinal Agents0
Sodium lauryl sulfoacetate1847-58-1Gastrointestinal Agents0
Sodium sulfate7757-82-6Laxatives6
Sodium zirconium cyclosilicate17141-74-1Gastrointestinal Agents0
Sofalcone64506-49-6Other gastrointestinal agents2
SorbitolLaxatives6
Starch900-25-8Laxatives5
Starches, hydroxyethylLaxatives4
Sucralfate54182-58-0Gastrointestinal Agents12
Tauroursodeoxycholic acid14605-22-2Bile acid preparations9
Teduglutide197922-42-2Gastrointestinal Agents4
Tegoprazan942195-55-3Gastrointestinal Agents0
Tenapanor1234423-95-0Gastrointestinal Agents0
Teprenone6809-52-5Gastrointestinal Agents0
Tetradecyl hydrogen sulfate (ester)300-52-7Gastrointestinal Agents0
Timepidium97094-64-9Gastrointestinal Agents0
Tocofersolan9002-96-4Gastrointestinal Agents0
Triheptanoin620-67-7Gastrointestinal Agents0
Trimebutine39133-31-8Motility inhibitors13
Trimethyldiphenylpropylamine13957-55-6Gastrointestinal Agents0
Troxipide30751-05-4Gastrointestinal Agents0
Ursodeoxycholic acid128-13-2Bile acid preparations29
Valethamate16376-74-2Gastrointestinal Agents0
Vonoprazan881681-00-1Proton pump inhibitors12
Wheat branLaxatives1
Zolimidine1222-57-7Gastrointestinal Agents0