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Date | Seller | Exporter country | Buyer | Importer country | Product | Quantity (KG) | Price per KG | Latest transactions |
---|---|---|---|---|---|---|---|---|
29-Oct-2022 | (Hidden) | India | T,D-E,A-S,... | Argentina | PANCRELIPA... | 200 | $ @36$-7! | Check all data |
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Looking for Pancrelipase API 53608-75-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pancrelipase. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pancrelipase
- Synonyms:
- PA , Pancreatic alpha-amylase precursor , Pancrelipase
- Cas Number:
- 53608-75-6
- DrugBank number:
- DB00085
- Unique Ingredient Identifier:
- FQ3DRG0N5K
About Pancrelipase
Want to know what Pancrelipase is used for? Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 2010. For further information on the components of this mixture please visit Pancrelipase amylase, Pancrelipase protease and Pancrelipase lipase.
Check who is selling Pancrelipase in the overview above.
Pancrelipase is a type of Pancreatic enzymes
Pancreatic enzymes are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of pancreatic insufficiency. This condition occurs when the pancreas fails to produce sufficient enzymes needed for proper digestion, leading to malabsorption of nutrients.
Pancreatic enzyme APIs are derived from porcine (pig) or microbial sources and contain a combination of enzymes such as lipases, amylases, and proteases. These enzymes aid in the breakdown of fats, carbohydrates, and proteins, respectively, facilitating the digestion and absorption of essential nutrients.
The pharmaceutical industry produces pancreatic enzyme APIs in compliance with stringent quality standards and regulations. The API manufacturing process involves extraction, purification, and formulation to ensure consistent enzyme activity and stability. The final API product is typically available in the form of enteric-coated capsules or tablets to protect the enzymes from premature degradation in the acidic environment of the stomach.
Physicians prescribe pancreatic enzyme API-based medications to patients with conditions like cystic fibrosis, chronic pancreatitis, and pancreatic cancer. These medications help patients improve their digestion, enhance nutrient absorption, and manage symptoms such as steatorrhea (fatty stool) and malnutrition.
Pancreatic enzyme APIs have demonstrated significant therapeutic benefits, supporting the overall well-being and quality of life for individuals with pancreatic insufficiency. Regular usage of these APIs, as prescribed by healthcare professionals, aids in the management of pancreatic disorders, ensuring optimal digestion and nutrient absorption.
Pancrelipase (Pancreatic enzymes), classified under Enzyme Replacements/modifiers
Enzyme replacements/modifiers are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various enzyme-related disorders. Enzymes play a vital role in the normal functioning of the body by catalyzing specific biochemical reactions. However, in certain medical conditions, the body may lack or produce dysfunctional enzymes, leading to serious health complications.
Enzyme replacement therapy (ERT) involves administering exogenous enzymes to compensate for the enzyme deficiency in patients. These enzymes are typically derived from natural sources or produced using recombinant DNA technology. By introducing these enzymes into the body, they can effectively substitute the missing or defective enzymes, thereby restoring normal metabolic processes.
On the other hand, enzyme modifiers are API substances that regulate the activity of specific enzymes within the body. These modifiers can either enhance or inhibit the enzyme's function, depending on the therapeutic objective. By modulating enzyme activity, these APIs can restore the balance of enzymatic reactions, leading to improved physiological outcomes.
Enzyme replacements/modifiers have shown remarkable success in treating various genetic disorders, such as Gaucher disease, Fabry disease, and lysosomal storage disorders. Additionally, they have demonstrated potential in managing enzyme deficiencies associated with rare diseases and certain types of cancer.
The development and production of enzyme replacements/modifiers involve rigorous research, formulation optimization, and adherence to stringent quality control measures. Pharmaceutical companies invest substantial resources in developing these APIs to ensure their safety, efficacy, and compliance with regulatory standards.
Overall, enzyme replacements/modifiers represent a vital therapeutic category in modern medicine, offering hope and improved quality of life for patients with enzyme-related disorders.
Pancrelipase manufacturers | traders | suppliers
We have 1 companies offering Pancrelipase produced in 1 different countries.
Get in contact with the supplier of your choice:
- Nordmark Arzneimittel from Germany, product country of origin Germany
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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