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Duloxetine API Manufacturers
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Produced in:
Established in: 1987
MOQ: 5 kg
Employees: 50+
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Passed ISO9001:2015 and SGS audit
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Provide one-stop CDMO service from R&D to production
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Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Produced in:
![Unknown Unknown](/build/images/flags/un-512px.cca7cda3.png)
Established in: 1963
MOQ: -
Employees: 800+
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World’s 1st exclusive API distributor
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Portfolio of 600+ APIs
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>250 clients in Europe
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Produced in:
Established in: 1923
MOQ: 25 kg
Employees: 20+
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Service-oriented company
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Global supply chain resilience
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Support of your new projects from start to commercial realisation
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Produced in:
![Unknown Unknown](/build/images/flags/un-512px.cca7cda3.png)
Established in: 1944
MOQ: -
Employees: 4,000
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14 international API plant sites
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Portfolio of 350+ APIs
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Teva is among the world’s largest generic drug/API manufacturers
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Looking for Duloxetine API 116539-59-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Duloxetine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Duloxetine
- Synonyms:
- Duloxetine hydrochloride
- Cas Number:
- 116539-59-4
- DrugBank number:
- DB00476
- Unique Ingredient Identifier:
- O5TNM5N07U
About Duloxetine
Why are people looking for Duloxetine? Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence. Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Duloxetine is a type of Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)
Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) belong to a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that have gained significant popularity in the treatment of various medical conditions. SNRIs work by modulating the levels of two essential neurotransmitters in the brain, namely serotonin and norepinephrine.
These APIs are commonly prescribed for managing a range of mental health disorders, including depression, anxiety disorders, and certain chronic pain conditions. By inhibiting the reuptake of serotonin and norepinephrine, SNRIs enhance their availability in the brain, leading to improved mood, increased energy levels, and reduced pain perception.
SNRIs exhibit a unique dual mechanism of action, making them distinct from other classes of antidepressant medications. By targeting both serotonin and norepinephrine reuptake, SNRIs provide a broader spectrum of therapeutic effects, making them effective in treating patients who do not respond well to other medications.
Due to their widespread usage and effectiveness, SNRIs have become a preferred choice for healthcare professionals. Some commonly prescribed SNRIs include duloxetine, venlafaxine, and desvenlafaxine. These APIs are typically available in oral formulations and are well-tolerated by most patients, with a favorable side effect profile.
In summary, SNRIs represent a significant subcategory of pharmaceutical APIs that play a crucial role in the management of mental health disorders and chronic pain conditions. Their unique dual mechanism of action and effectiveness make them a valuable treatment option for healthcare providers, ensuring improved patient outcomes and quality of life.
Duloxetine (Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)), classified under Antidepressants
Antidepressants are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of depression and other mood disorders. These medications work by balancing the levels of certain chemicals in the brain called neurotransmitters, such as serotonin, norepinephrine, and dopamine.
There are several types of antidepressants available, each with its own mechanism of action and efficacy. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a first-line treatment for depression. They prevent the reabsorption of serotonin, resulting in increased serotonin levels in the brain. Examples of popular SSRIs include fluoxetine, sertraline, and escitalopram.
Tricyclic antidepressants (TCAs) are another class of antidepressants that work by blocking the reuptake of both serotonin and norepinephrine. They are generally used when SSRIs are ineffective or not well-tolerated. Amitriptyline, nortriptyline, and imipramine are commonly prescribed TCAs.
Other antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). SNRIs, such as venlafaxine and duloxetine, inhibit the reuptake of both serotonin and norepinephrine. Atypical antidepressants, including bupropion and mirtazapine, have diverse mechanisms of action, targeting multiple neurotransmitters. MAOIs, such as phenelzine and tranylcypromine, work by inhibiting the enzyme monoamine oxidase, which breaks down neurotransmitters.
It is important to note that antidepressants may have various side effects and require close monitoring by healthcare professionals. Dosages and treatment duration vary based on individual needs and response. Antidepressants are typically prescribed as part of a comprehensive treatment plan that may include psychotherapy and lifestyle modifications.
In conclusion, antidepressants are a vital category of pharmaceutical APIs used to manage depression and related mood disorders. They act on neurotransmitters in the brain to alleviate symptoms and improve overall well-being. It is crucial to consult with a healthcare provider to determine the most suitable antidepressant and monitor its effects.
Duloxetine manufacturers | traders | suppliers
We have 25 companies offering Duloxetine produced in 8 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Kolon Life Science from South Korea, product country of origin South Korea
- Signa from Mexico, product country of origin Mexico
- Eli Lilly And Company from United States, product country of origin United States
- KRKA from Slovenia, product country of origin Unknown
- Huadong Medicine from China, product country of origin China
- Zhejiang Yongtai Pharma from China, product country of origin China
- Alkem Labs. from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Zhejiang Liaoyuan from China, product country of origin China
- HEC Pharm from Germany, product country of origin Unknown
- Otto Brandes GmbH from Germany, product country of origin China
- Zhejiang Tiantai from China, product country of origin China
- Zhejiang Huayi from China, product country of origin China
- Torrent Pharma from India, product country of origin India
- Teva API from Israel, product country of origin Unknown
- Menovo from China, product country of origin China
- Lupin from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Mylan from India, product country of origin India
- Jubilant Generics from India, product country of origin Unknown
- Hetero Drugs from India, product country of origin Unknown
- Erregierre from Italy, product country of origin Italy
- Moehs from Spain, product country of origin Spain
- MSN Labs. from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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