Duloxetine API Manufacturers

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Located in:

China

Produced in:

China

Established in: 1987

MOQ: 5 kg

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

China

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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Located in:

Slovenia

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Produced in:

Unknown

MOQ: -

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Located in:

China

Produced in:

China

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Located in:

China

Produced in:

China

MOQ: -

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Located in:

Germany

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Produced in:

Unknown

MOQ: -

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Located in:

China

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China

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Located in:

South Korea

Produced in:

South Korea

MOQ: -

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India

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India

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United States

Produced in:

United States

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India

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India

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China

Produced in:

China

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India

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India

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Located in:

China

Produced in:

China

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Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Located in:

China

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Produced in:

China

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Located in:

China

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China

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Located in:

China

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Unknown

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India

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Located in:

Mexico

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Produced in:

Mexico

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Located in:

India

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Produced in:

India

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Located in:

Spain

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Produced in:

Spain

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Located in:

India

Produced in:

Unknown

MOQ: -

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Located in:

India

Produced in:

Unknown

MOQ: -

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Located in:

Italy

Producer

Produced in:

Italy

MOQ: -

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Located in:

India

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Produced in:

India

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Located in:

India

Producer

Produced in:

India

MOQ: -

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Looking for Duloxetine API 116539-59-4?

Description:
Here you will find a list of producers, manufacturers and distributors of Duloxetine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Duloxetine 
Synonyms:
Duloxetine hydrochloride  
Cas Number:
116539-59-4 
DrugBank number:
DB00476 
Unique Ingredient Identifier:
O5TNM5N07U

About Duloxetine

Why are people looking for Duloxetine? Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence. Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Duloxetine is a type of Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)


Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) belong to a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that have gained significant popularity in the treatment of various medical conditions. SNRIs work by modulating the levels of two essential neurotransmitters in the brain, namely serotonin and norepinephrine.

These APIs are commonly prescribed for managing a range of mental health disorders, including depression, anxiety disorders, and certain chronic pain conditions. By inhibiting the reuptake of serotonin and norepinephrine, SNRIs enhance their availability in the brain, leading to improved mood, increased energy levels, and reduced pain perception.

SNRIs exhibit a unique dual mechanism of action, making them distinct from other classes of antidepressant medications. By targeting both serotonin and norepinephrine reuptake, SNRIs provide a broader spectrum of therapeutic effects, making them effective in treating patients who do not respond well to other medications.

Due to their widespread usage and effectiveness, SNRIs have become a preferred choice for healthcare professionals. Some commonly prescribed SNRIs include duloxetine, venlafaxine, and desvenlafaxine. These APIs are typically available in oral formulations and are well-tolerated by most patients, with a favorable side effect profile.

In summary, SNRIs represent a significant subcategory of pharmaceutical APIs that play a crucial role in the management of mental health disorders and chronic pain conditions. Their unique dual mechanism of action and effectiveness make them a valuable treatment option for healthcare providers, ensuring improved patient outcomes and quality of life.


Duloxetine (Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)), classified under Antidepressants


Antidepressants are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of depression and other mood disorders. These medications work by balancing the levels of certain chemicals in the brain called neurotransmitters, such as serotonin, norepinephrine, and dopamine.

There are several types of antidepressants available, each with its own mechanism of action and efficacy. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a first-line treatment for depression. They prevent the reabsorption of serotonin, resulting in increased serotonin levels in the brain. Examples of popular SSRIs include fluoxetine, sertraline, and escitalopram.

Tricyclic antidepressants (TCAs) are another class of antidepressants that work by blocking the reuptake of both serotonin and norepinephrine. They are generally used when SSRIs are ineffective or not well-tolerated. Amitriptyline, nortriptyline, and imipramine are commonly prescribed TCAs.

Other antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). SNRIs, such as venlafaxine and duloxetine, inhibit the reuptake of both serotonin and norepinephrine. Atypical antidepressants, including bupropion and mirtazapine, have diverse mechanisms of action, targeting multiple neurotransmitters. MAOIs, such as phenelzine and tranylcypromine, work by inhibiting the enzyme monoamine oxidase, which breaks down neurotransmitters.

It is important to note that antidepressants may have various side effects and require close monitoring by healthcare professionals. Dosages and treatment duration vary based on individual needs and response. Antidepressants are typically prescribed as part of a comprehensive treatment plan that may include psychotherapy and lifestyle modifications.

In conclusion, antidepressants are a vital category of pharmaceutical APIs used to manage depression and related mood disorders. They act on neurotransmitters in the brain to alleviate symptoms and improve overall well-being. It is crucial to consult with a healthcare provider to determine the most suitable antidepressant and monitor its effects.



Duloxetine manufacturers | traders | suppliers

We have 28 companies offering Duloxetine produced in 8 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Otto Brandes GmbH from Germany, product country of origin China
  • KRKA from Slovenia, product country of origin Unknown
  • Zhejiang Tiantai from China, product country of origin China
  • Zhejiang Liaoyuan from China, product country of origin China
  • HEC Pharm from Germany, product country of origin Unknown
  • Chongqing Shenghuaxi from China, product country of origin China
  • Kolon Life Science from South Korea, product country of origin South Korea
  • Lupin from India, product country of origin India
  • Eli Lilly And Company from United States, product country of origin United States
  • Torrent Pharma from India, product country of origin India
  • Zhejiang Yongtai Pharma from China, product country of origin China
  • Alkem Labs. from India, product country of origin India
  • Huadong Medicine from China, product country of origin China
  • Teva API from Israel, product country of origin Unknown
  • Menovo from China, product country of origin China
  • Zhejiang Huayi from China, product country of origin China
  • Qilu Pharma from China, product country of origin Unknown
  • Megafine Pharma (P) Ltd. from India, product country of origin India
  • Signa from Mexico, product country of origin Mexico
  • Mylan from India, product country of origin India
  • Moehs from Spain, product country of origin Spain
  • Jubilant Generics from India, product country of origin Unknown
  • Hetero Drugs from India, product country of origin Unknown
  • Erregierre from Italy, product country of origin Italy
  • MSN Labs. from India, product country of origin India
  • Sun Pharma from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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