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Established in: 1968
MOQ: 5 kg
Employees: 50+
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Looking for Oxitriptan API 4350-09-8?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Oxitriptan. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Oxitriptan
- Synonyms:
- Cincofarm , Hydroxy-5 L-tryptophane , L-5-Hydroxytryptophan , Levothym , Oxitriptan , Tript-OH , Oxitriptanum
- Cas Number:
- 4350-09-8
- DrugBank number:
- DB02959
- Unique Ingredient Identifier:
- C1LJO185Q9
About Oxitriptan
Some technical information about this product: 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and is also marketed in many European countries for the indication of major depression under trade names like Cincofarm, Levothym, Levotonine, Oxyfan, Telesol, Tript-OH, and Triptum. Several double-blind placebo-controlled clinical trials have demonstrated the effectiveness of 5-HTP in the treatment of depression, though a lack of high quality studies has been noted. More study is needed to determine efficacy in treating depression.
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Oxitriptan is a type of Serotonin receptor agonists
Serotonin receptor agonists are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that have shown potential in the treatment of various medical conditions. These compounds work by binding to and activating serotonin receptors in the body, which play a crucial role in regulating mood, appetite, sleep, and other physiological functions. By stimulating these receptors, serotonin receptor agonists can modulate serotonin signaling and produce therapeutic effects.
One prominent application of serotonin receptor agonists is in the treatment of migraines. Migraine headaches are often associated with abnormal serotonin levels and receptor activity. Serotonin receptor agonists, such as triptans, bind to specific serotonin receptor subtypes (e.g., 5-HT1B and 5-HT1D) in the brain's blood vessels, causing vasoconstriction and reducing inflammation. This action helps alleviate the severe pain and other symptoms associated with migraines.
Additionally, serotonin receptor agonists are being investigated for their potential in the management of psychiatric disorders, such as depression and anxiety. These compounds can modulate serotonin transmission, leading to improved mood and reduced anxiety levels. Research is also exploring their role in treating other conditions like irritable bowel syndrome (IBS), fibromyalgia, and cluster headaches.
As the development of serotonin receptor agonists progresses, scientists are focusing on optimizing their selectivity and potency while minimizing potential side effects. Pharmaceutical companies are actively engaged in synthesizing novel compounds and conducting clinical trials to assess their efficacy and safety profiles. The ongoing research and development in this subcategory hold promise for improved treatment options and enhanced patient outcomes in various serotonin-related disorders.
Oxitriptan (Serotonin receptor agonists), classified under Central Nervous System Agents
Central Nervous System (CNS) Agents are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that specifically target the central nervous system. The CNS encompasses the brain and spinal cord, playing a vital role in regulating and controlling various bodily functions, including cognition, movement, emotions, and sensory perception. These agents are designed to interact with specific receptors, enzymes, or ion channels within the CNS to modulate neural activity and restore normal functioning.
CNS agents comprise a diverse range of pharmaceutical APIs, including analgesics, anesthetics, antipsychotics, sedatives, hypnotics, anti-epileptics, and antidepressants. Each subcategory addresses distinct neurological disorders and conditions. For instance, analgesics alleviate pain by targeting receptors in the brain and spinal cord, while antipsychotics are employed to manage psychosis symptoms in mental illnesses such as schizophrenia.
The development of CNS agents involves rigorous research, molecular modeling, and extensive clinical trials to ensure safety, efficacy, and specific target engagement. Pharmaceutical companies invest significant resources in identifying novel drug targets, synthesizing new compounds, and optimizing their pharmacological properties. These agents undergo rigorous regulatory evaluations and must adhere to stringent quality standards and guidelines.
Given the prevalence of CNS disorders globally, the market demand for effective CNS agents is substantial. The development of innovative CNS APIs not only improves patient outcomes but also provides valuable commercial opportunities for pharmaceutical companies. Continued advancements in CNS agent research and development hold the promise of groundbreaking therapies that can improve the quality of life for individuals affected by neurological conditions.
Oxitriptan manufacturers | traders | suppliers
We have 2 companies offering Oxitriptan produced in 2 different countries.
Get in contact with the supplier of your choice:
- Duchefa Farma B.V. from Netherlands, product country of origin Switzerland
- Norchim from France, product country of origin France
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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