Dapagliflozin API Manufacturers

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Located in:

India

Producer

Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

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Located in:

Poland

Producer

Produced in:

Poland

Established in: 1951

MOQ: -

Employees: 455+

Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.

FDA approved european manufcaturing facilities

Export APIs to more than 60 countries worldwide

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Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Located in:

Iran

Producer

Produced in:

Iran

Established in: 1956

MOQ: 1 kg

Employees: 200+

Expertise in Low Volume, High Value (LVHV) APIs

Technical knowledge for high-tech API production

therapeutic production sites with GMP compliance

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2014

MOQ: -

Employees: 1000+

22 years of production experience

6 workshops and 9 production lines which has 100t/month production capacity

4 USDMFS & 5 CEPS & 200+ Patents

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Located in:

India
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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 1 g

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

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Produced in:

China

Established in: 2011

MOQ: 10 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

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Located in:

India

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Located in:

India

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China

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Located in:

France

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Located in:

China
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Located in:

China
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Producer

Produced in:

India

Established in: 1995

MOQ: -

Employees: 10000

Fermentation technology Experts

Partnerships with 1200 pharma companies in 100+ countries

US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations

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Produced in:

India

Established in: 1983

MOQ: -

Employees: 200+

Presence in more than 75 countries in the world

We delivery top quality APIs as per global standards

manufacture 45+ APIs including 10 essential drugs

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Located in:

India

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Located in:

India

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Located in:

India

Located in:

China

Located in:

Germany

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Located in:

India

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Located in:

India
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Located in:

India
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Looking for Dapagliflozin API 461432-26-8?

Description:
Here you will find a list of producers, manufacturers and traders of Dapagliflozin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dapagliflozin 
Synonyms:
Dapagliflozin Amorphous , Dapagliflozin Propanediol  
Cas Number:
461432-26-8 
DrugBank number:
DB06292 
Unique Ingredient Identifier:
1ULL0QJ8UC

About Dapagliflozin

Here you will find more information about Dapagliflozin. Dapagliflozin is a sodium-glucose cotransporter 2 inhibitor indicated for managing diabetes mellitus type When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose resorption in the proximal tubule of the nephron and causing glycosuria1. Dapagliflozin was approved by the FDA on Jan 08, 20143.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Dapagliflozin is a type of SGLT2-inhibitors


SGLT2 inhibitors, short for Sodium-Glucose Co-Transporter 2 inhibitors, belong to the pharmaceutical API subcategory utilized in the treatment of type 2 diabetes mellitus (T2DM). These innovative drugs target the SGLT2 protein responsible for reabsorbing glucose in the kidneys, resulting in increased urinary glucose excretion.

By inhibiting SGLT2, these drugs effectively lower blood glucose levels and improve glycemic control in patients with T2DM. This mechanism of action is independent of insulin secretion or sensitivity, making SGLT2 inhibitors an attractive option for individuals who are resistant to or cannot tolerate other diabetes medications.

Some commonly prescribed SGLT2 inhibitors include canagliflozin, dapagliflozin, and empagliflozin. These pharmaceutical APIs are typically formulated into oral tablets, making them convenient for patient administration.

Clinical studies have demonstrated the effectiveness of SGLT2 inhibitors in reducing HbA1c levels, body weight, and blood pressure in patients with T2DM. Additionally, these medications have shown potential cardiovascular benefits, including a decreased risk of cardiovascular events.

However, it is important to note that SGLT2 inhibitors are not suitable for everyone, and their use should be carefully considered in patients with renal impairment or a history of ketoacidosis. Adverse effects may include genitourinary infections and increased risk of dehydration.

Overall, SGLT2 inhibitors are a promising class of pharmaceutical APIs that offer an innovative approach to managing T2DM by targeting renal glucose reabsorption. Ongoing research and development in this field aim to further optimize the therapeutic potential of SGLT2 inhibitors and improve patient outcomes.


Dapagliflozin (SGLT2-inhibitors), classified under Anti-diabetics


Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.



Dapagliflozin manufacturers | traders | suppliers

We have 28 companies offering Dapagliflozin produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Dr. Reddy's from India, product country of origin India
  • Polpharma from Poland, product country of origin Poland
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Tofigh Daru from Iran, product country of origin Iran
  • Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
  • Solfyn International LLP from India, product country of origin China
  • Senova Technology Co., Ltd. from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Morepen Laboratories Ltd. from India, product country of origin India
  • Raks Pharma from India, product country of origin India
  • Hikal from India, product country of origin India
  • ALP PHARM from China, product country of origin China
  • Honour Lab from India, product country of origin India
  • Lupin from India, product country of origin India
  • Jiangsu Hansoh Pharma from China, product country of origin China
  • Finorga from France, product country of origin France
  • Jiangxi Aifeimu Technology Co Ltd from China, product country of origin China
  • Fuxing Long Rui Pharma from China, product country of origin China
  • Biocon from India, product country of origin India
  • Harman Finochem from India, product country of origin India
  • Micro Labs from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Piramal Pharma Solutions from India, product country of origin India
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Siegfried from Germany, product country of origin Germany
  • MSN Labs. from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India
  • ZCL Chemicals from India, product country of origin India

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