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Located in:

India

Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

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HIGHLIGHTED

Located in:

Switzerland

Distributor

Produced in:

United Kingdom

Established in: 1865

MOQ: -

Employees: 33,000+

Valid Regulatory support

Marketing Intelligence to stay on trend and ahead in the market

Tailored value-added services that support the increase of market potential

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Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

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Produced in:

India

Established in: 2018

MOQ: -

Employees: 200+

WHO GMP Approved sites for production

25+ years experience in manufacturing APIs for regulated markets

High quality product & superior client service

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Produced in:

China

Established in: 2011

MOQ: 100 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Produced in:

India

Established in: 1995

MOQ: -

Employees: 10000

Fermentation technology Experts

Partnerships with 1200 pharma companies in 100+ countries

US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations

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Looking for Rosuvastatin API 287714-41-4?

Description:
Here you will find a list of producers, manufacturers and traders of Rosuvastatin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Rosuvastatin 
Synonyms:
Rosuvastatin calcium , Rosuvastatin Calcium Crystalline , Rosuvastatin Calcium Amorphous  
Cas Number:
287714-41-4 
DrugBank number:
DB01098 
Unique Ingredient Identifier:
413KH5ZJ73

About Rosuvastatin

Some technical information about this product: Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase4 which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as bad cholesterol), and very low-density lipoprotein (VLDL). Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America.
 

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Rosuvastatin is a type of Statins

Statins are a widely prescribed class of pharmaceutical active ingredients (APIs) used for the treatment of high cholesterol and prevention of cardiovascular diseases. These medications work by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver.


Statins are categorized as lipid-lowering agents and are highly effective in reducing levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol. By decreasing LDL cholesterol, statins help to prevent the formation of plaque in the arteries, reducing the risk of heart attacks and strokes.

There are several popular statins available on the market, including atorvastatin, simvastatin, rosuvastatin, and pravastatin. Each statin differs in terms of potency, dosing, and potential drug interactions, allowing healthcare professionals to select the most appropriate option for individual patients.

Statins are typically taken orally in the form of tablets or capsules and are available in different strengths. The dosage is determined by various factors such as the patient's cholesterol levels, cardiovascular risk, and response to treatment.

While statins are generally well-tolerated, they can have side effects such as muscle pain, liver dysfunction, and gastrointestinal disturbances. However, these side effects are relatively rare and are outweighed by the significant cardiovascular benefits of statin therapy.

In conclusion, statins are a vital subclass of pharmaceutical APIs used for managing high cholesterol and reducing the risk of cardiovascular diseases. They effectively lower LDL cholesterol levels and are an essential component of treatment plans for individuals with hyperlipidemia or a high risk of heart disease.


Rosuvastatin (Statins), classified under Lipid-lowering agents


Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.

One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.

Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.

Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.

Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.

It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.



Rosuvastatin manufacturers | traders | suppliers

We have 47 companies offering Rosuvastatin from 7 different countries.

Get in contact with the supplier of your choice:

  • Morepen Laboratories Ltd. from India
  • DKSH from Switzerland
  • Apino Pharma Co., Ltd. from China
  • Gonane Pharma from India
  • Shandong Octagon Chemicals Limited from China
  • Zhejiang Jiangbei from China
  • Melody Healthcare from India
  • Shanghai Desano Chem. from China
  • Hanmi Fine Chemical from South Korea
  • Zhejiang Neo-Dankong from China
  • Menovo from China
  • Jeil Pharmaceutical from South Korea
  • Lupin from India
  • Amoli Organics from India
  • Unnati Pharmaceuticals Pvt Ltd from India
  • Signa from Mexico
  • G.C. Chemie Pharmie Ltd from India
  • Changzhou Pharmaceutical Factory from China
  • Nantong Chanyoo from China
  • Yungjin Pharmaceutical from South Korea
  • Humble Healthcaare from India
  • Lee Pharma from India
  • Hiral Labs from India
  • HEC Pharm from Germany
  • Rui Laboratories Private Limited from India
  • Jinan Jinda from China
  • Changzhou Pharma from China
  • Saintsun Pharma Co Ltd from China
  • API Corp. from Japan
  • Kolon Life Science from South Korea
  • Cadila Healthcare from India
  • Jiangxi Aifeimu Technology Co Ltd from China
  • Changzhou ComWin from China
  • Zhejiang Hisun Pharma from China
  • Teva API from Israel
  • Zhejiang Hongyuan from China
  • Biocon from India
  • MSN Labs. from India
  • Shaoxing Hantai Pharma from China
  • Mylan from India
  • Jubilant Generics from India
  • Aurobindo from India
  • Optimus Drugs Pvt Ltd from India
  • Sun Pharma from India
  • Lek Pharma from Slovenia
  • Hetero Drugs from India
  • Glenmark Pharma from India

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